Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772447 | 1.00 | SQOR (0.49) | SQORKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL12427715 | 0.97 | SQOR (0.46) | SQORKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL28623786 | 0.84 | NPC1 (0.52) | SQORKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL29817390 | 0.83 | CD274 (0.62) | SQOR | |
| SCHEMBL14931777 | 0.83 | ALDH1A1 (0.58) | SQORKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL12427713 | 0.83 | TDO2 (0.38) | SQORKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL12427717 | 0.83 | NPSR1 (0.40) | SQORKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL12427716 | 0.80 | F2RL3 (0.40) | KDM4EALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8218294 | 0.79 | LMNA (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL12427721 | 0.79 | KDM1A (0.45) | KDM4EALDH1A1SMN1; SMN2HSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330595-B | pyridine derivatives and their use as antimycobacterial agents | 上海嘉坦医药科技有限公司 | 2019-12-10 | — | — | CN | disclosed |
| EP-3170810-B1 | PYRIDINE DERIVATIVES AND ANTI-MYCOBACTERIAL USE THEREOF | CISEN PHARMACEUTICAL CO LTD (CN) | 2018-09-19 | — | — | EP | disclosed |
| US-9878982-B2 | Pyridine derivatives and anti-mycobacterial use thereof | CISEN PHARMACEUTICAL CO., LTD. (CN) | 2018-01-30 | — | — | US | disclosed |
| US-9878982-B2 | Pyridine derivatives and anti-mycobacterial use thereof | CISEN PHARMACEUTICAL CO., LTD. (CN) | 2018-01-30 | — | — | US | disclosed |
| US-9878982-B2 | Pyridine derivatives and anti-mycobacterial use thereof | CISEN PHARMACEUTICAL CO., LTD. (CN) | 2018-01-30 | — | — | US | disclosed |
| US-20170174628-A1 | PYRIDINE DERIVATIVES AND ANTI-MYCOBACTERIAL USE THEREOF | CISEN PHARMACEUTICAL CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
| US-20170174628-A1 | PYRIDINE DERIVATIVES AND ANTI-MYCOBACTERIAL USE THEREOF | CISEN PHARMACEUTICAL CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
| US-20170174628-A1 | PYRIDINE DERIVATIVES AND ANTI-MYCOBACTERIAL USE THEREOF | CISEN PHARMACEUTICAL CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
| EP-3170810-A1 | PYRIDINE DERIVATIVES AND ANTI-MYCOBACTERIAL USE THEREOF | Cisen Pharmaceutical Co. Ltd. (CN) | 2017-05-24 | — | — | EP | disclosed |
| EP-3170810-A1 | PYRIDINE DERIVATIVES AND ANTI-MYCOBACTERIAL USE THEREOF | Cisen Pharmaceutical Co. Ltd. (CN) | 2017-05-24 | — | — | EP | disclosed |
| EP-2310371-B1 | PPAR AGONIST COMPOUNDS AND PREPARATION AND USES THEREOF FOR TREATING DIABETES AND/OR DYSLIPIDEMIA | GENFIT (FR) | 2013-05-15 | — | — | EP | disclosed |
| EP-2310371-B1 | PPAR AGONIST COMPOUNDS AND PREPARATION AND USES THEREOF FOR TREATING DIABETES AND/OR DYSLIPIDEMIA | GENFIT (FR) | 2013-05-15 | — | — | EP | disclosed |
| US-20110195993-A1 | PPAR AGONIST COMPOUNDS, PREPARATION AND USES | GENFIT (FR) | 2011-08-11 | — | — | US | disclosed |
| EP-1730203-B1 | CATALYST COMPOSITION AND USE THEREOF | EXXONMOBIL CHEM PATENTS INC (US) | 2008-12-31 | — | — | EP | disclosed |
| US-7423101-B2 | Catalyst composition and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-09-09 | — | — | US | disclosed |
| US-20080071047-A1 | Catalyst Composition And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-03-20 | — | — | US | disclosed |
| US-7317057-B2 | Catalyst composition and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-01-08 | — | — | US | disclosed |
| EP-1730203-A1 | CATALYST COMPOSITION AND USE THEREOF | ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005095469-A1 | CATALYST COMPOSITION AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-10-13 | — | — | WO | disclosed |
| US-20050209420-A1 | Catalyst composition and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195993-A1 | PPAR AGONIST COMPOUNDS, PREPARATION AND USES | PPARD, PPARA, PPARG | SQOR 1609/4885KDM4E 3040/4885ALDH1A1 1483/4885 |
| US-20050209420-A1 | Catalyst composition and use thereof | DGAT1, DGAT2, ALOX5 | SQOR 223/4885KDM4E 2093/4885ALDH1A1 2505/4885 |
| US-20170174628-A1 | PYRIDINE DERIVATIVES AND ANTI-MYCOBACTERIAL USE THEREOF | ME3, SSBP1, MDH2 | SQOR 99/4885KDM4E 2492/4885ALDH1A1 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.