Sugi Predict

Sugi Predict / Compounds / SCHEMBL486726

SCHEMBL486726

SCHEMBL486726

CS(=N)(=O)c1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ MAPK1 P28482 1/20 0.56
▸ CA1 P00915 4/20 0.52
▸ CA2 P00918 4/20 0.52
▸ CA12 O43570 3/20 0.52
▸ CA3 P07451 3/20 0.52
▸ CA4 P22748 3/20 0.52
▸ CA6 P23280 3/20 0.52
▸ CA5A P35218 3/20 0.52
▸ CA7 P43166 3/20 0.52
▸ CA9 Q16790 3/20 0.52
▸ CA13 Q8N1Q1 3/20 0.52
▸ CA14 Q9ULX7 3/20 0.52
▸ CA5B Q9Y2D0 3/20 0.52
▸ PTGS2 P35354 4/20 0.48
▸ ALOX15 P16050 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265232 0.79 PTGS2 (0.69) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL25983703 0.77 ALDH1A1 (0.59) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL488382 0.77 GAA (0.59) ALDH1A1CYP3A4CA1CA2CA12
SCHEMBL2281688 0.76 ALDH1A1 (0.48) ALDH1A1CA1CA2CA12CA9
SCHEMBL23145865 0.75 ENPP2 (0.41) CA1CA2CA12CA3CA6
SCHEMBL2290762 0.75 PTGS2 (0.48) ALDH1A1CA1CA2PTGS2MMP1
SCHEMBL9628601 0.75 CA2 (0.52) CA1CA2CA12CA9CA14
SCHEMBL3929345 0.75 TSHR (0.56) ALDH1A1CYP3A4CA1CA2CA12
SCHEMBL17642663 0.75 CA1 (0.46) CA1CA2CA12CA9PTGS2
SCHEMBL28530917 0.75 TSHR (0.40) ALDH1A1CYP3A4MAPK1PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179012-A1 SYNTHESIS OF SULFUR(VI) COMPOUNDS AND REAGENTS FOR SAME H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2025-06-05 — — US disclosed
CN-117305865-A Electrochemical method for preparing N-aroyl sulfoxide imine compound 桂林理工大学 2023-12-29 — — CN disclosed
WO-2023168108-A2 SYNTHESIS OF SULFUR(VI) COMPOUNDS AND REAGENTS FOR SAME H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2023-09-07 — — WO disclosed
CN-110698431-B Synthetic method of 1, 2-benzothiazine compound 陕西师范大学 2022-07-01 — — CN disclosed
CN-110698431-A Synthetic method of 1, 2-benzothiazine compound 陕西师范大学 2020-01-17 — — CN disclosed
EP-2268615-B1 PESTICIDES DOW AGROSCIENCES LLC (US) 2016-08-17 — — EP disclosed
US-8445689-B2 Pesticides DOW AGROSCIENCES, LLC. (US) 2013-05-21 — — US disclosed
US-20120225782-A1 PESTICIDES DOW AGROSCIENCES LLC (US) 2012-09-06 — — US disclosed
US-8178685-B2 Pesticides DOW AGROSCIENCES, LLC (US) 2012-05-15 — — US disclosed
EP-1511725-B1 24-SULFOXIMINE VITAMIN D3 COMPOUNDS UNIV JOHNS HOPKINS (US) 2012-02-01 — — EP disclosed
US-20090226377-A1 NOVEL SULPHOXIMINE-SUBSTITUTED QUINOLINE AND QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS BAYER HEALTHCARE LLC (DE) 2009-09-10 — — US disclosed
US-20090221424-A1 PESTICIDES DOW AGROSCIENCES LLC (US) 2009-09-03 — — US disclosed
WO-2008141843-A1 NOVEL SULPHOXIMINE-SUBSTITUTED QUINAZOLINE AND QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-11-27 — — WO disclosed
US-20060217353-A1 24-sulfoximine vitamin D3 compounds CYTOCHROMA INC. (CA) 2006-09-28 — — US disclosed
US-7101865-B2 24-sulfoximine vitamin D3 compounds CYTOCHROMA INC. (CA) 2006-09-05 — — US disclosed
EP-1511725-A1 24-SULFOXIMINE VITAMIN D sb 3 /sb COMPOUNDS Johns Hopkins University (US) 2005-03-09 — — EP disclosed
US-20040038949-A1 24-sulfoximine vitamin D3 compounds JOHNS HOPKINS UNIVERSITY 2004-02-26 — — US disclosed
WO-2003106411-A1 24-SULFOXIMINE VITAMIN D3 COMPOUNDS JOHNS HOPKINS UNIVERSITY (US) 2003-12-24 — — WO disclosed
US-4556413-A POSTEMERGENCE AND PREEMERGENCE HERBICIDES HOFFMANN-LA ROCHE INC. (US) 1985-12-03 — — US disclosed
EP-0109575-A2 Benzoic-acid derivatives, process and means for its production F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-05-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038949-A1 24-sulfoximine vitamin D3 compounds CYP24A1, CYP2R1, CYP27B1 ALDH1A1 376/4885CYP3A4 139/4885MAPK1 3343/4885
US-20120225782-A1 PESTICIDES ACHE, DDT, GSTP1 ALDH1A1 1009/4885CYP3A4 95/4885MAPK1 4832/4885
US-20090221424-A1 PESTICIDES ACHE, DDT, GSTP1 ALDH1A1 1009/4885CYP3A4 95/4885MAPK1 4833/4885
US-20090226377-A1 NOVEL SULPHOXIMINE-SUBSTITUTED QUINOLINE AND QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS MAP4K2, MAP3K20, MAP3K2 ALDH1A1 3510/4885CYP3A4 2883/4885MAPK1 130/4885
US-20060217353-A1 24-sulfoximine vitamin D3 compounds CYP24A1, CYP2R1, CYP27B1 ALDH1A1 303/4885CYP3A4 132/4885MAPK1 3251/4885
US-20250179012-A1 SYNTHESIS OF SULFUR(VI) COMPOUNDS AND REAGENTS FOR SAME TST, CBS, SQOR ALDH1A1 2224/4885CYP3A4 701/4885MAPK1 3365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.