SCHEMBL5137502

SCHEMBL5137502

Ic1ccc2cccnc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
LMNA P02545 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP3A4 P08684 2/20 0.46
HTT P42858 2/20 0.46
GMNN O75496 1/20 0.46
TP53 P04637 1/20 0.46
HSP90AA1 P07900 1/20 0.46
MMP2 P08253 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
MMP9 P14780 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
MMP8 P22894 1/20 0.46
CCR1 P32246 1/20 0.46
THPO P40225 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28304525 0.77 CCR1 (0.55) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL29354893 0.77 CCR1 (0.55) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL8193 0.77 CCR1 (0.55) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL1089189 0.76 ALDH1A1 (0.55) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL11131062 0.76 CCR1 (0.70) ALDH1A1LMNAKDM4ECYP3A4HTT
Ammonia Solution, Strong SCHEMBL2732606 0.75 CCR1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A
Water SCHEMBL8327751 0.75 CCR1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL16337846 0.75 CCR1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL3704753 0.75 CCR1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL3710471 0.75 CCR1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023356-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-20240018175-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-11864400-B2 Organic light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-02 US disclosed
US-11825740-B2 Amine compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
US-20230354694-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, ELECTONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-02 US disclosed
US-20230329103-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 US disclosed
US-11744146-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-29 US disclosed
US-11690289-B2 Organic compound containing heterocyclic ring and having low lumo properties, and organic electroluminescent device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-27 US disclosed
US-20230200221-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE CONDENSED CYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230180606-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 US disclosed
US-6306874-B1 ENZYME INHIBITORS SUCH AS ANGIOGENESIS, CANCER, TUMOR GROWTH, ATHEROSCLEROSIS, AGE RELATED MACULAR DEGENERATION, DIABETIC RETINOPATHY, INFLAMMATORY DISEASES, AND THE LIKE IN MAMMALS. MERCK & CO., INC. 2001-10-23 US disclosed
WO-2001029025-A2 TYROSINE KINASE INHIBITORS MERCK & CO., INC. (US) 2001-04-26 WO disclosed
EP-0060012-B1 4-HALO-1,8-NAPHTHYRIDINE DERIVATIVES USEFUL AS INTERMEDIATES AND PROCESSES FOR THEIR PREPARATION AMERICAN HOME PRODUCTS CORPORATION (US) 1984-08-29 EP disclosed
EP-0018735-B1 1,8-NAPHTHYRIDINE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AMERICAN HOME PRODUCTS CORPORATION (US) 1983-07-27 EP disclosed
US-4350817-A 4-Cl, Br or I-3-Carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1982-09-21 US disclosed
EP-0060012-A1 4-Halo-1,8-naphthyridine derivatives useful as intermediates and processes for their preparation AMERICAN HOME PRODUCTS CORPORATION (US) 1982-09-15 EP disclosed
US-4347362-A HYPOTENSIVE AMERICAN HOME PRODUCTS CORPORATION (US) 1982-08-31 US disclosed
US-4324893-A 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1982-04-13 US disclosed
EP-0018735-A1 1,8-Naphthyridine derivatives, their preparation, pharmaceutical compositions containing them AMERICAN HOME PRODUCTS CORPORATION (US) 1980-11-12 EP disclosed
WO-1980002287-A1 1,8-NAPHTHYRIDINE DERIVATIVES AMERICAN HOME PROD (US) 1980-10-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230200221-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE CONDENSED CYCLIC COMPOUND CRY1, CRY2, ELP1 ALDH1A1 269/4885LMNA 1532/4885KDM4E 3561/4885
US-20240018175-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT INCLUDING THE LIGHT-EMITTING DEVICE GPX1, LAGE3, NFE2L2 ALDH1A1 17/4885LMNA 4552/4885KDM4E 913/4885
US-11690289-B2 Organic compound containing heterocyclic ring and having low lumo properties, and organic electroluminescent device using the same LEF1, PPOX, LIMK1 ALDH1A1 111/4885LMNA 469/4885KDM4E 1153/4885
US-11744146-B2 Amine-based compound and organic light-emitting device including the same AOC2, AOC1, EML4 ALDH1A1 76/4885LMNA 2076/4885KDM4E 655/4885
US-11825740-B2 Amine compound and organic light-emitting device including the same AOC2, AOC1, AOC3 ALDH1A1 19/4885LMNA 2049/4885KDM4E 1194/4885
US-20230354694-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, ELECTONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE LAGE3, ELP1, EML4 ALDH1A1 98/4885LMNA 4338/4885KDM4E 1805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.