SCHEMBL5147935

SCHEMBL5147935

CCCCCCCCc1ccc(OC(COCCS(=O)(=O)[O-])OCC)cc1.[Na+]

nearest known ligand 0.40

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 2/20 0.39
THRB known ✓ P10828 2/20 0.36
THRA known ✓ P10827 1/20 0.36
FUT7 Q11130 1/20 0.40
PPARA Q07869 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
KMT2A Q03164 1/20 0.39
SLCO1B3 Q9NPD5 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
S1PR1 P21453 6/20 0.37
S1PR2 O95136 3/20 0.37
S1PR3 Q99500 2/20 0.37
S1PR4 O95977 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5490686 0.88 S1PR1 (0.48) PPARASMN1; SMN2MEN1USP2ALDH1A1
SCHEMBL9452145 0.82 CA2 (0.40) FUT7SMN1; SMN2MEN1USP2ALDH1A1
SCHEMBL9395348 0.82 CNR2 (0.33) S1PR1
SCHEMBL8365259 0.81 ALDH1A1 (0.44) PPARASMN1; SMN2MEN1USP2ALDH1A1
SCHEMBL4459952 0.78 MEN1 (0.64) FUT7SMN1; SMN2MEN1USP2ALDH1A1
SCHEMBL27518731 0.78 MEN1 (0.64) FUT7SMN1; SMN2MEN1USP2ALDH1A1
SCHEMBL28437698 0.75 MEN1 (0.55) FUT7SMN1; SMN2MEN1USP2ALDH1A1
SCHEMBL8679002 0.75 S1PR1 (0.47) PPARASMN1; SMN2MEN1USP2ALDH1A1
SCHEMBL9393646 0.74 MEN1 (0.53) FUT7SMN1; SMN2MEN1USP2ALDH1A1
SCHEMBL9418699 0.73 ALDH1A1 (0.49) PPARASMN1; SMN2MEN1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7172856-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-02-06 US disclosed
EP-1365285-B1 A method for processing a silver halide color photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2006-11-02 EP disclosed
EP-1271241-B1 Method for processing silver halide color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2006-04-05 EP disclosed
US-7022469-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2006-04-04 US disclosed
US-6952294-B2 Method of reading an image, method of forming a color image, device for forming a color image, silver halide color photosensitive material, and a device for processing a photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
EP-0743558-B1 Photographic processing composition and processing method FUJI PHOTO FILM CO LTD (JP) 2005-08-03 EP disclosed
US-6852481-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-02-08 US disclosed
US-6838231-B2 Production process of silver halide photographic emulsion and silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-01-04 US disclosed
US-6815156-B2 HEXAGONAL TABULAR SILVER HALIDE GRAIN HAVING A SMOOTH FACE AS A PRINCIPAL PLANE, HIGH SILVER IODIDE CONTENT, PROJECTED AREA DIAMETER; EXCELLENT IN THE RATIO OF SENSITIVITY/GRANULARITY, FORMING A BLUE- SENSITIVE LAYER FUJI PHOTO FILM CO., LTD. (JP) 2004-11-09 US disclosed
US-20040202974-A1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2004-10-14 US disclosed
US-5230993-A Subbing layer having cationic polymer, ammonium or phosphonium salts; for medical use or nondestructive testing FUJI PHOTO FILM CO., LTD. (JP) 1993-07-27 US disclosed
US-5190855-A Hydroxypolyazaindene Complexing Agent FUJI PHOTO FILM CO., LTD. (JP) 1993-03-02 US disclosed
EP-0476521-A2 Silver halide photographic material and method for processing the same FUJI PHOTO FILM CO., LTD. (JP) 1992-03-25 EP disclosed
EP-0476535-A1 Photographic material FUJI PHOTO FILM CO., LTD. (JP) 1992-03-25 EP disclosed
US-4965170-A REDUCIBLE, TIME-RELEASING DYE COMPOUND; NONDIFFUSING; ANTISOILANTS; ALSO INCLUDING A HIGH-CONTRAST HYDRAZINE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1990-10-23 US disclosed
US-4965180-A SUPPORT, SUBBING LAYER, AQUEOUS POLYMER LATEX FUJII PHOTO FILM CO., LTD. (JP) 1990-10-23 US disclosed
US-4942114-A FLUORESCENT, REFLECTIVE FUJI PHOTO FILM CO., LTD. (JP) 1990-07-17 US disclosed
US-4917993-A HYDROPHILIC COLLOID LAYER AND WATER SOLUBLE POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
EP-0321948-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-28 EP disclosed
EP-0320962-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-06-21 EP disclosed