Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 3/20 | 0.32 |
| ▸ | CCND1 | P24385 | 3/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20104372 | 0.74 | CYP2A6 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL20104369 | 0.71 | ESR1 (0.33) | MAPK9MAPK10 | |
| SCHEMBL8647146 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6068564 | 0.71 | ADORA3 (0.33) | L3MBTL1SMN1; SMN2PBRM1MEN1KMT2A | |
| SCHEMBL1368461 | 0.69 | CA12 (0.35) | CA12CA9ALDH1A1BRD4BRPF1 | |
| SCHEMBL29769926 | 0.69 | CA12 (0.35) | CA12CA9ALDH1A1BRD4BRPF1 | |
| SCHEMBL18751059 | 0.67 | CA12 (0.37) | CA12CA9ALDH1A1BRD4BRPF1 | |
| SCHEMBL18750707 | 0.65 | NPC1 (0.40) | CA12CA9ALDH1A1BRD4BRPF1 | |
| SCHEMBL9136994 | 0.64 | NPC1 (0.46) | ALDH1A1MAPTL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL1368459 | 0.64 | KMT2A (0.46) | CA12CA9ALDH1A1BRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105355-B | Preparation method of 1,2, 3-triazole- [1,5-a ] quinoline compound | 烟台大学 | 2021-09-21 | — | — | CN | claimed |
| US-9034486-B2 | Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) | 2015-05-19 | — | — | US | claimed |
| WO-2012017842-A1 | TRIAZOLE DERIVATIVE, HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-02-09 | — | — | WO | claimed |
| US-20120025697-A1 | Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-02-02 | — | — | US | claimed |
| EP-0745154-B1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM | LIGNOZYM GMBH (DE) | 1998-09-16 | — | — | EP | claimed |
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-01-02 | — | — | US | disclosed |
| CN-110105355-B | Preparation method of 1,2, 3-triazole- [1,5-a ] quinoline compound | 烟台大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-110105355-B | Preparation method of 1,2, 3-triazole- [1,5-a ] quinoline compound | 烟台大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-110105355-B | Preparation method of 1,2, 3-triazole- [1,5-a ] quinoline compound | 烟台大学 | 2021-09-21 | — | — | CN | disclosed |
| EP-3153498-B1 | N-SUBSTITUTED PHENYL GLYCINE PREPARATION METHOD | ABA CHEMICALS CORP (CN) | 2019-08-21 | — | — | EP | disclosed |
| CN-110105355-A | A kind of preparation method of 1,2,3- triazole-[1,5-a] and quinolines | 烟台大学 | 2019-08-09 | — | — | CN | disclosed |
| US-10280134-B1 | Potent cytotoxic agent against human hepatocellular carcinoma cell line based on 2-aryl hydrazonopropanal pharmacophore | KING ABDULAZIZ UNIVERSITY (SA) | 2019-05-07 | — | — | US | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110112106-A1 | TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-05-12 | — | — | US | disclosed |
| US-7919621-B2 | Tricyclic inhibitors of 5-lipoxygenase | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20100204278-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | MERCK SHARP & DOHME CORP. | 2010-08-12 | — | — | US | disclosed |
| WO-2010086089-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-08-05 | — | — | WO | disclosed |
| US-20070173508-A1 | TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| WO-2002081474-A1 | TRIAZOLOPHTHALAZINE / QUINOLINE / ISOQUINOLINE DERIVATIVES WHICH ARE LIGANDS FOR GABA-A RECEPTORS CONTAINING THE ALPHA 5 SUBTYPE | MERCK SHARP & DOHME LIMITED (GB) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002081474-A1 | TRIAZOLOPHTHALAZINE / QUINOLINE / ISOQUINOLINE DERIVATIVES WHICH ARE LIGANDS FOR GABA-A RECEPTORS CONTAINING THE ALPHA 5 SUBTYPE | MERCK SHARP & DOHME LIMITED (GB) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173508-A1 | TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE | ALOX5, ALOX15, ALOX15B | CA12 4856/4885CA9 4094/4885ALDH1A1 802/4885 |
| US-20110112106-A1 | TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE | ALOX5, ALOX15, ALOX15B | CA12 4856/4885CA9 4094/4885ALDH1A1 802/4885 |
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CGAS, TDP1, CYP11B2 | CA12 390/4885CA9 538/4885ALDH1A1 987/4885 |
| US-20110284799-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | CA12 1141/4885CA9 1868/4885ALDH1A1 3721/4885 |
| US-10280134-B1 | Potent cytotoxic agent against human hepatocellular carcinoma cell line based on 2-aryl hydrazonopropanal pharmacophore | HCCS, HDGF, HAVCR2 | CA12 1139/4885CA9 1724/4885ALDH1A1 42/4885 |
| US-20100204278-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | HCAR1, HCAR2, FFAR1 | CA12 4003/4885CA9 3501/4885ALDH1A1 1181/4885 |
| US-20120025697-A1 | Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device | HTR3D, KCNQ4, KCNQ3 | CA12 4799/4885CA9 4550/4885ALDH1A1 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.