SCHEMBL52197

SCHEMBL52197

Cc1ccc2sc3cc(CN4CCOCC4)ccc3c(=O)c2c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.48
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
CA2 P00918 1/20 0.46
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
ATM Q13315 1/20 0.45
PARP1 P09874 3/20 0.45
ILK Q13418 1/20 0.44
HRH3 Q9Y5N1 1/20 0.41
HTT P42858 1/20 0.41
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
TP53 P04637 2/20 0.40
TNKS O95271 1/20 0.40
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29501109 1.00 HSD17B10 (0.48) HSD17B10CRHBPCRHR2CA2RAB9A
SCHEMBL15124980 0.88 CRHBP (0.50) HSD17B10CRHBPCRHR2HRH3ALDH1A1
SCHEMBL51864 0.84 CRHBP (0.60) CRHBPCRHR2CA2RAB9ANPC1
SCHEMBL29501108 0.84 CRHBP (0.60) CRHBPCRHR2CA2RAB9ANPC1
SCHEMBL3859111 0.83 CRHBP (0.43) HSD17B10CRHBPCRHR2CA2RAB9A
SCHEMBL31536358 0.82 CRHBP (0.44) HSD17B10CRHBPCRHR2RAB9ANPC1
SCHEMBL14985633 0.76 ALDH1A1 (0.50) RAB9ANPC1TP53ALDH1A1SMN1; SMN2
SCHEMBL17261595 0.73 CRHBP (0.44) CRHBPCRHR2RAB9ANPC1ATM
SCHEMBL20878759 0.72 KDM4E (0.41) RAB9ANPC1TP53ALDH1A1SMN1; SMN2
SCHEMBL1609870 0.72 KDM4E (0.51) RAB9ANPC1TP53ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11382868-B2 Transdermal UV-curable hydrogel resin, hydrogel curing the same and cataplasm containing the same ICURE PHARMACEUTICAL INC. (KR) 2022-07-12 US claimed
US-10919909-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2021-02-16 US claimed
US-20190211031-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2019-07-11 US claimed
US-20190046463-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME ICURE PHARMACEUTICAL INC. (KR) 2019-02-14 US claimed
EP-3415141-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME Icure Pharmaceutical Inc. (KR) 2018-12-19 EP claimed
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set RESONAC CORPORATION (JP) 2026-05-26 US disclosed
EP-4743828-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2026-05-20 EP disclosed
US-20260132243-A1 THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF, PHOTOMELTABLE COMPOSITION, AND STRUCTURAL BODY PRODUCTION METHOD RESONAC CORP (JP) 2026-05-14 US disclosed
EP-4555025-B1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS, FURTHER ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B V (NL) 2026-05-13 EP disclosed
EP-3902878-B1 PHOTOINITIATORS IGM RESINS ITALIA SRL (IT) 2026-05-06 EP disclosed
EP-4410859-B1 THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF, PHOTO-MELTABLE COMPOSITION, AND STRUCTURAL BODY PRODUCTION METHOD RESONAC CORP (JP) 2026-04-29 EP disclosed
EP-4534614-B1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS, FURTHER ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B V (NL) 2026-04-15 EP disclosed
EP-0425440-B1 Method of adjusting the photosensitivity of photopolymerizable compositions CIBA GEIGY AG (CH) 1994-11-17 EP disclosed
EP-0287516-B1 PHOTOPOLYMERIZABLE ADHESIVES CIBA-GEIGY AG (CH) 1993-03-31 EP disclosed
US-5145885-A Morpholine compound, binders CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
EP-0425440-A1 Method of adjusting the photosensitivity of photopolymerizable compositions CIBA-GEIGY AG (CH) 1991-05-02 EP disclosed
US-4992547-A Aminoaryl ketone photoinitiators CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
EP-0287516-A2 Photopolymerizable adhesives CIBA-GEIGY AG (CH) 1988-10-19 EP disclosed
EP-0138754-B1 PHOTOCURABLE COMPOSITIONS CIBA-GEIGY AG (CH) 1988-05-25 EP disclosed
EP-0138754-A2 Photocurable compositions CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set ESD, CDH1, ASH2L HSD17B10 937/4885CRHBP 4544/4885CRHR2 4218/4885
US-10919909-B2 Photoinitiated reactions KMO, DECR1, PPOX HSD17B10 264/4885CRHBP 4478/4885CRHR2 4485/4885
US-20190211031-A1 PHOTOINITIATED REACTIONS DOHH, PAH, DBH HSD17B10 443/4885CRHBP 4745/4885CRHR2 4812/4885
US-20260132243-A1 THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF, PHOTOMELTABLE COMPOSITION, AND STRUCTURAL BODY PRODUCTION METHOD RER1, OXTR, MAP1LC3A HSD17B10 1159/4885CRHBP 2049/4885CRHR2 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.