Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959854 | 0.94 | FABP3 (0.42) | FABP3CNR1CNR2TRPV1 | |
| Potassium Ion SCHEMBL15842271 | 0.91 | FABP3 (0.44) | FABP3CNR1CNR2TRPV1 | |
| SCHEMBL13505366 | 0.88 | EPHX2 (0.55) | EPHX2 | |
| SCHEMBL13505363 | 0.88 | EPHX2 (0.55) | EPHX2 | |
| SCHEMBL20786762 | 0.87 | EPHX2 (0.54) | EPHX2 | |
| SCHEMBL29797805 | 0.87 | EPHX2 (0.54) | EPHX2 | |
| SCHEMBL1960221 | 0.87 | EPHX2 (0.54) | EPHX2 | |
| SCHEMBL14937708 | 0.86 | GPR84 (0.40) | FABP3 | |
| SCHEMBL874378 | 0.84 | CNR1 (0.61) | FABP3CNR1CNR2TRPV1EPHX2 | |
| SCHEMBL10613227 | 0.84 | CNR1 (0.61) | FABP3CNR1CNR2TRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078211-A1 | A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE | DOW TORAY CO LTD (JP) | 2026-03-19 | — | — | US | disclosed |
| EP-3368592-B1 | COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN | DOW TORAY CO LTD (JP) | 2025-12-03 | — | — | EP | disclosed |
| EP-4626941-A1 | A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE | Dow Toray Co., Ltd. (JP) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024113195-A1 | A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE | DOW TORAY CO., LTD. (JP) | 2024-06-06 | — | — | WO | disclosed |
| US-11820846-B2 | Composition, method of preparing copolymer, and methods and end uses thereof | DOW SILICONES CORPORATION (US) | 2023-11-21 | — | — | US | disclosed |
| EP-2492301-B1 | NOVEL CO-MODIFIED ORGANOPOLYSILOXANE | DOW TORAY CO LTD (JP) | 2023-03-29 | — | — | EP | disclosed |
| US-20220213309-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION, COSMETIC INGREDIENT, COATING FORMING AGENT, AND COSMETIC CONTAINING SAME | DOW TORAY CO., LTD. (JP) | 2022-07-07 | — | — | US | disclosed |
| US-20220112322-A1 | COMPOSITION, METHOD OF PREPARING COPOLYMER, AND METHODS AND END USES THEREOF | DOW TORAY CO., LTD. (JP) | 2022-04-14 | — | — | US | disclosed |
| EP-3950727-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION, COSMETIC INGREDIENT, COATING FORMING AGENT, AND COSMETIC CONTAINING SAME | Dow Toray Co., Ltd. (JP) | 2022-02-09 | — | — | EP | disclosed |
| US-20210386651-A1 | METHOD OF DESIGNING FILM-FORMING AGENT OR COSMETIC CONTAINING THE SAME | DOW TORAY CO LTD (JP) | 2021-12-16 | — | — | US | disclosed |
| WO-2011136393-A1 | ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL -BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011136389-A2 | COSMETIC AND TOPICAL SKIN PREPARATION COMPRISING HIGHER ALCOHOL-MODIFIED SILICONE | DOW CORNING TORAY CO., LTD. (JP) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011136397-A1 | NOVEL ORGANOPOLYSILOXANE, SURFACTANT, EMULSION COMPOSITION, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL, GELLING AGENT, GEL COMPOSITION, AND COSMETIC RAW MATERIAL COMPRISING NOVEL ORGANOPOLYSILOXANE, AS WELL AS, PREPARATION FOR EXTERNAL USE AND COSMETIC COMPRISING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2011-11-03 | — | — | WO | disclosed |
| US-8034891-B2 | Polyether-modified organopolysiloxane, diorganopolysiloxane-polyether block copolymer, their production methods, and cosmetic preparation | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-10-11 | — | — | US | disclosed |
| WO-2011068251-A1 | PRODUCTION METHOD OF DEODORIZED POLYOXYALKYLENE-MODIFIED POLYSILOXANE COMPOSITION | DOW CORNING TORAY CO., LTD. (JP) | 2011-06-09 | — | — | WO | disclosed |
| US-20100036062-A1 | Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation | DOW TORAY CO., LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20100028391-A1 | Cosmetics Comprising A Modified Organopolysiloxane | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2022812-A1 | POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION | Dow Corning Toray Co., Ltd. (JP) | 2009-02-11 | — | — | EP | disclosed |
| EP-1895979-A1 | COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE | Dow Corning Toray Co., Ltd. (JP) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006137576-A1 | COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO., LTD. (JP) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100028391-A1 | Cosmetics Comprising A Modified Organopolysiloxane | H1-0, H1-2, CHRM1 | FABP3 4741/4885CNR1 477/4885CNR2 1329/4885 |
| US-20260078211-A1 | A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE | FOXM1, FOXK1, TAF1L | FABP3 3111/4885CNR1 2884/4885CNR2 3797/4885 |
| US-11820846-B2 | Composition, method of preparing copolymer, and methods and end uses thereof | BRS3, OXSR1, OXER1 | FABP3 2831/4885CNR1 1090/4885CNR2 1047/4885 |
| US-20210386651-A1 | METHOD OF DESIGNING FILM-FORMING AGENT OR COSMETIC CONTAINING THE SAME | WASHC5, WASHC4, CUTA | FABP3 2720/4885CNR1 3046/4885CNR2 3766/4885 |
| US-20220213309-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION, COSMETIC INGREDIENT, COATING FORMING AGENT, AND COSMETIC CONTAINING SAME | ADCY1, ADORA1, ADCY8 | FABP3 4858/4885CNR1 678/4885CNR2 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.