Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388790 | 0.81 | TAAR1 (0.39) | TAAR1RIPK1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL704259 | 0.80 | SLC6A4 (0.41) | TAAR1RIPK1SLC6A4SLC6A3ATM | |
| SCHEMBL704632 | 0.78 | ATM (0.37) | TAAR1RIPK1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3526378 | 0.77 | F2 (0.39) | TAAR1RIPK1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3951516 | 0.77 | TAAR1 (0.37) | TAAR1RIPK1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL705569 | 0.77 | RIPK1 (0.37) | TAAR1RIPK1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11770112 | 0.76 | TAAR1 (0.40) | TAAR1RIPK1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL706206 | 0.75 | LMNA (0.41) | RIPK1SLC6A4SLC6A3SLC6A2AOC3 | |
| SCHEMBL7074781 | 0.74 | TAAR1 (0.39) | TAAR1RIPK1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL707571 | 0.74 | RIPK1 (0.35) | TAAR1RIPK1SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375779-A | Method for stereoselective synthesis of 2' -deoxyribonucleoside | 中国药科大学 | 2023-07-04 | — | — | CN | claimed |
| US-10662202-B2 | Synthesis of cephalosporin compounds | MERCK SHARP & DOHM CORP. (US) | 2020-05-26 | — | — | US | claimed |
| US-10632099-B2 | Non-aromatic difluoro analogues of resorcylic acid lactones | UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2020-04-28 | — | — | US | claimed |
| US-20180153854-A1 | NON-AROMATIC DIFLUORO ANALOGUES OF RESORCYLIC ACID LACTONES | NORTH CAROLINA AT GREENSBORO, UNIVERSITY OF | 2018-06-07 | — | — | US | claimed |
| EP-2308861-B1 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS | EISAI R&D MAN CO LTD (JP) | 2017-03-01 | — | — | EP | claimed |
| EP-1910387-B1 | COMPOUNDS FOR PREPARING IMMUNOLOGICAL ADJUVANT | EISAI R&D MAN CO LTD (JP) | 2016-11-16 | — | — | EP | claimed |
| EP-2427057-B1 | BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS | SLOAN KETTERING INST CANCER (US) | 2015-08-12 | — | — | EP | claimed |
| US-20130217900-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | UNITED PHOSPHORUS LIMITED (IN) | 2013-08-22 | — | — | US | claimed |
| US-7915306-B2 | For therapy of inflammatory or autoimmune disorders | EISAI CO., LTD. (JP) | 2011-03-29 | — | — | US | claimed |
| US-7683200-B2 | Compounds for preparing immunological adjuvant | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2010-03-23 | — | — | US | claimed |
| US-11986481-B2 | Method of synthesizing thyroid hormone analogs and polymorphs thereof | MADRIGAL PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20240148742-A1 | METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF | MADRIGAL PHARMACEUTICALS, INC. | 2024-05-09 | — | — | US | disclosed |
| EP-4023641-B1 | METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF | MADRIGAL PHARMACEUTICALS INC (US) | 2024-05-01 | — | — | EP | disclosed |
| US-11964025-B2 | Peptide-containing linkers for antibody-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2024-04-23 | — | — | US | disclosed |
| US-20240122936-A1 | METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF | LSI FINANCING LLC, AS ADMINISTRATIVE AGENT | 2024-04-18 | — | — | US | disclosed |
| US-4681962-A | BLOOD PLATELET ANTI-AGGREGATING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1987-07-21 | — | — | US | disclosed |
| US-4680419-A | ANTHELMINTICS | THE UPJOHN COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| US-4680415-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1987-07-14 | — | — | US | disclosed |
| EP-0209694-A1 | Novel prostacyclins | F. HOFFMANN-LA ROCHE AG (CH) | 1987-01-28 | — | — | EP | disclosed |
| US-4634782-A | PROSTAGLANDINS, ANTICOAGULANTS, HYPOTENSIVES | HOFFMANN-LA ROCHE INC. (US) | 1987-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662202-B2 | Synthesis of cephalosporin compounds | COASY, DDT, PEPD | TAAR1 4511/4885RIPK1 3011/4885SLC6A4 3836/4885 |
| US-11986481-B2 | Method of synthesizing thyroid hormone analogs and polymorphs thereof | THRB, TSHR, TRHR | TAAR1 1396/4885RIPK1 3507/4885SLC6A4 1583/4885 |
| US-20240122936-A1 | METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF | THRB, TSHR, TRHR | TAAR1 1396/4885RIPK1 3507/4885SLC6A4 1583/4885 |
| US-20130217900-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | CYP21A2, HRH3, P4HA1 | TAAR1 501/4885RIPK1 4058/4885SLC6A4 811/4885 |
| US-20240148742-A1 | METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF | THRB, TSHR, TRHR | TAAR1 1396/4885RIPK1 3507/4885SLC6A4 1583/4885 |
| US-20180153854-A1 | NON-AROMATIC DIFLUORO ANALOGUES OF RESORCYLIC ACID LACTONES | FRS2, FGFR3, FDPS | TAAR1 4461/4885RIPK1 1664/4885SLC6A4 3603/4885 |
| US-11964025-B2 | Peptide-containing linkers for antibody-drug conjugates | CD2BP2, DNPEP, LNPEP | TAAR1 4062/4885RIPK1 2630/4885SLC6A4 3603/4885 |
| US-10632099-B2 | Non-aromatic difluoro analogues of resorcylic acid lactones | FRS2, FGFR3, FDPS | TAAR1 4461/4885RIPK1 1664/4885SLC6A4 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.