SCHEMBL5469033

SCHEMBL5469033

CSc1c(CC(C)N)ccc2c1OCO2

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 4/20 0.49
SLC6A2 P23975 3/20 0.49
SLC6A3 Q01959 3/20 0.49
TAAR1 Q96RJ0 2/20 0.49
MAOA P21397 1/20 0.37
HTR2C P28335 4/20 0.35
HTR2B P41595 4/20 0.35
HTR2A P28223 3/20 0.35
HTR1A P08908 3/20 0.35
HTR6 P50406 2/20 0.35
HTR4 Q13639 2/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2C P18825 1/20 0.35
HTR1B P28222 1/20 0.35
HTR1D P28221 1/20 0.35
HTR7 P34969 1/20 0.35
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31220876 1.00 SLC6A4 (0.49) SLC6A4SLC6A2SLC6A3TAAR1MAOA
SCHEMBL1067408 0.80 TAAR1 (0.53) SLC6A4SLC6A2SLC6A3TAAR1HTR2C
SCHEMBL23389329 0.78 TAAR1 (0.51) SLC6A4SLC6A2SLC6A3TAAR1HTR2C
SCHEMBL394419 0.78 TAAR1 (0.58) SLC6A4SLC6A2SLC6A3TAAR1MAOA
SCHEMBL2776318 0.77 TAAR1 (0.50) SLC6A4SLC6A2SLC6A3TAAR1HTR2C
SCHEMBL30886885 0.76 CYP3A4 (0.39) HTR2CHTR2BHTR2AHTR1AHTR6
SCHEMBL2556563 0.76 TAAR1 (0.49) SLC6A4SLC6A2SLC6A3TAAR1
SCHEMBL30289794 0.70 TAAR1 (0.53) SLC6A4SLC6A2SLC6A3TAAR1MAOA
SCHEMBL5780889 0.70 AOC3 (0.36)
SCHEMBL29633082 0.69 HTR2A (0.51) TAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2026-04-23 US disclosed
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US disclosed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-10 US disclosed
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-03 US disclosed
US-20260048048-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2026-02-19 US disclosed
US-20250376436-A1 Selective Serotonin Receptor Modulators and Methods of Making and Using the Same Park City Bio, LLC (US) 2025-12-11 US disclosed
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS KULEON LLC (US) 2025-11-06 US disclosed
US-20250325533-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2025-10-23 US disclosed
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same Kuleon, LLC (US) 2025-10-14 US disclosed
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-25 US disclosed
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-11 US disclosed
US-20210251976-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2021-08-19 US disclosed
WO-2021101926-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH STAMETS PAUL EDWARD (US) 2021-05-27 WO disclosed
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-05-20 US disclosed
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-03-11 US disclosed
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CAAMTECH, INC. 2019-05-16 US disclosed
US-20150025063-A1 Antiparkinsonian Action of Phenylisopropylamines UNIV DUKE (US) 2015-01-22 US disclosed
US-8877802-B2 Antiparkinsonian action of phenylisopropylamines Duke Univerity (US) 2014-11-04 US disclosed
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (18 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CNR1, CNR2, HTR5A SLC6A4 317/4885SLC6A2 1008/4885SLC6A3 1233/4885
US-20250376436-A1 Selective Serotonin Receptor Modulators and Methods of Making and Using the Same HTR1A, HTR4, HTR5A SLC6A4 18/4885SLC6A2 28/4885SLC6A3 41/4885
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 SLC6A4 47/4885SLC6A2 56/4885SLC6A3 54/4885
US-20210251976-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF SLC6A4 62/4885SLC6A2 168/4885SLC6A3 178/4885
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT SLC6A4 178/4885SLC6A2 97/4885SLC6A3 36/4885
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF SLC6A4 62/4885SLC6A2 168/4885SLC6A3 178/4885
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A SLC6A4 137/4885SLC6A2 258/4885SLC6A3 204/4885
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same HTR7, HTR2C, HTR1A SLC6A4 21/4885SLC6A2 52/4885SLC6A3 39/4885
US-20260048048-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF SLC6A4 44/4885SLC6A2 115/4885SLC6A3 125/4885
US-20250325533-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, BDNF, HTR6 SLC6A4 90/4885SLC6A2 233/4885SLC6A3 234/4885
US-20150025063-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT SLC6A4 178/4885SLC6A2 97/4885SLC6A3 36/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B SLC6A4 28/4885SLC6A2 31/4885SLC6A3 63/4885
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS HTR2A, HTR2C, HTR3A SLC6A4 26/4885SLC6A2 43/4885SLC6A3 59/4885
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF SLC6A4 62/4885SLC6A2 168/4885SLC6A3 178/4885
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A SLC6A4 137/4885SLC6A2 258/4885SLC6A3 204/4885
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same HTR1D, HTR1A, HTR4 SLC6A4 19/4885SLC6A2 38/4885SLC6A3 45/4885
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same HTR5A, HTR1A, HTR1D SLC6A4 21/4885SLC6A2 98/4885SLC6A3 53/4885
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF SLC6A4 26/4885SLC6A2 46/4885SLC6A3 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.