Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287690 | 0.81 | GAA (0.62) | GAACA1CA2CA12CA3 | |
| SCHEMBL12807 | 0.78 | GAA (0.65) | GAACA1CA2CA12CA3 | |
| SCHEMBL28182477 | 0.78 | GAA (0.65) | GAACA1CA2CA12CA3 | |
| SCHEMBL8780038 | 0.77 | PTGS2 (0.57) | GAACA1CA2CA12CA3 | |
| SCHEMBL904300 | 0.77 | GAA (0.56) | GAACA1CA2CA12CA3 | |
| SCHEMBL8320274 | 0.76 | HTR6 (0.52) | CA1CA2CA12CA3CA6 | |
| Iodide SCHEMBL10338838 | 0.76 | GAA (0.62) | GAACA1CA2CA12CA3 | |
| Water SCHEMBL17653839 | 0.76 | GAA (0.62) | GAACA1CA2CA12CA3 | |
| SCHEMBL514614 | 0.76 | GAA (0.62) | GAACA1CA2CA12CA3 | |
| SCHEMBL547554 | 0.75 | GAA (0.68) | GAACA1CA2CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017135472-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | ＥＡファーマ株式会社 | 2017-08-10 | — | — | WO | disclosed |
| US-20170158880-A1 | ABSORPTIVE PIGMENTS COMPRISING GRAPHENIC CARBON PARTICLES | PPG INDUSTRIES OHIO, INC. | 2017-06-08 | — | — | US | disclosed |
| US-20170107205-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-04-20 | — | — | US | disclosed |
| US-9522145-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-12-20 | — | — | US | disclosed |
| US-9475946-B2 | Graphenic carbon particle co-dispersions and methods of making same | PPG INDUSTRIES OHIO, INC. (US) | 2016-10-25 | — | — | US | disclosed |
| US-20160304525-A1 | Cyclopenta[d]pyrimidines And Substituted Cyclopenta[d]pyrimidines As Antitubulin and Microtubule Targeting Agents, Monocyclic Pyrimidines As Tubulin Inhibitors, And Pyrrolopyrimidines As Targeted Antifolates And Tubulin and Multiple Receptor Tyrosine Kinase Inhibition And Antitumor Agents | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT | 2016-10-20 | — | — | US | disclosed |
| US-20160272572-A1 | ADENYLYL CYCLASE INHIBITORS FOR NEUROPATHIC AND INFLAMMATORY PAIN | PURDUE RESEARCH FOUNDATION | 2016-09-22 | — | — | US | disclosed |
| US-20160272572-A1 | ADENYLYL CYCLASE INHIBITORS FOR NEUROPATHIC AND INFLAMMATORY PAIN | PURDUE RESEARCH FOUNDATION | 2016-09-22 | — | — | US | disclosed |
| US-20160145265-A1 | METHOD AND APPARATUS FOR THE SYNTHESIS OF DIHYDROARTEMISININ AND ARTEMISININ DERIVATIVES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-05-26 | — | — | US | disclosed |
| US-20160143898-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-05-26 | — | — | US | disclosed |
| US-20130143892-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | NEUROCRINE BIOSCIENCES, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| EP-2173717-B1 | NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME | BRISTOL MYERS SQUIBB CO (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20130018030-A1 | New compounds, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-17 | — | — | US | disclosed |
| US-20120322784-A1 | Compounds, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20120322798-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120308724-A1 | COATING COMPOSITIONS THAT TRANSMIT INFRARED RADIATION AND EXHIBIT COLOR STABILITY AND RELATED COATING SYSTEMS | PPG IDUSTRIES OHIO, I NC. (US) | 2012-12-06 | — | — | US | disclosed |
| US-8129466-B2 | efficient dispersion of organic or inorganic pigment particles, in a tri-block copolymer having a first block of glycidyl (meth)acrylate reacted with 3-hydroxy-2-napthoic Acid, second and third blocks of butyl methacrylate, hydroxypropyl methacrylate, butyl acrylate; coatings, inks, primer, topcoat | PPG INDUSTRIES OHIO, INC (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110190409-A1 | LADDER POLYMERS WITH INSTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2011-08-04 | — | — | US | disclosed |
| US-20100047620-A1 | SOLAR REFLECTIVE COATINGS AND COATING SYSTEMS | PPG INDUSTRIES OHIO, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20080188610-A1 | PIGMENT DISPERSANT | PPG INDUSTRIES OHIO, INC. (US) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322784-A1 | Compounds, pharmaceutical compositions and uses thereof | GPR119, GPR3, MRGPRX2 | GAA 829/4885CA1 4043/4885CA2 1334/4885 |
| US-20170107205-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | GAA 347/4885CA1 4884/4885CA2 2789/4885 |
| US-20130018030-A1 | New compounds, pharmaceutical compositions and uses thereof | GPR119, GPR3, MRGPRX2 | GAA 879/4885CA1 3921/4885CA2 1669/4885 |
| US-20160143898-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | GAA 347/4885CA1 4884/4885CA2 2789/4885 |
| US-20160304525-A1 | Cyclopenta[d]pyrimidines And Substituted Cyclopenta[d]pyrimidines As Antitubulin and Microtubule Targeting Agents, Monocyclic Pyrimidines As Tubulin Inhibitors, And Pyrrolopyrimidines As Targeted Antifolates And Tubulin and Multiple Receptor Tyrosine Kinase Inhibition And Antitumor Agents | FOLR1, TUBB1, TUBA1C | GAA 3877/4885CA1 4150/4885CA2 2743/4885 |
| US-20120322798-A1 | Modulators of ATP-Binding Cassette Transporters | CFTR, ABCB1, ABCC2 | GAA 339/4885CA1 4884/4885CA2 2614/4885 |
| US-20110190409-A1 | LADDER POLYMERS WITH INSTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF | CCR3, CNOT9, AR | GAA 4529/4885CA1 3814/4885CA2 3773/4885 |
| US-20160145265-A1 | METHOD AND APPARATUS FOR THE SYNTHESIS OF DIHYDROARTEMISININ AND ARTEMISININ DERIVATIVES | ADH1A, DHODH, DHPS | GAA 1510/4885CA1 665/4885CA2 2503/4885 |
| US-20160272572-A1 | ADENYLYL CYCLASE INHIBITORS FOR NEUROPATHIC AND INFLAMMATORY PAIN | ADCY1, ADCY2, ADCY5 | GAA 2153/4885CA1 2851/4885CA2 832/4885 |
| US-20130143892-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | GPR119, GPBAR1, TACR1 | GAA 1517/4885CA1 4694/4885CA2 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.