SCHEMBL5724032

SCHEMBL5724032

CC(C)N(CC(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
CA1 P00915 3/20 0.33
CA7 P43166 2/20 0.33
CA2 P00918 2/20 0.33
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
CA14 Q9ULX7 4/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
CA12 O43570 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18634785 0.84 HDAC6 (0.33) HDAC6HDAC1HDAC2CA1CA7
SCHEMBL3901647 0.84 HDAC6 (0.32) HDAC6HDAC1HDAC2CA1CA7
SCHEMBL5724498 0.83 HDAC6 (0.33) HDAC6HDAC1HDAC2CA1CA7
SCHEMBL18285697 0.83 CA14 (0.37) HDAC6HDAC1HDAC2CA1CA7
SCHEMBL5724221 0.81 CA14 (0.40) HDAC6HDAC1HDAC2CA1CA7
SCHEMBL6888470 0.81 CTSS (0.36) HDAC6HDAC1HDAC2CTSSCTSK
SCHEMBL19837575 0.80 CA14 (0.32) HDAC6HDAC1HDAC2CA14
SCHEMBL18400312 0.80 CA14 (0.36) HDAC6HDAC1HDAC2CA1CA7
SCHEMBL342022 0.80 GABRR1 (0.35) HDAC6MEN1GAAKMT2A
SCHEMBL342023 0.80 GABRR1 (0.35) HDAC6MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-04-02 US disclosed
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-02-12 US disclosed
US-12485109-B2 Pyrrolo 12.3-dipyrimidine compounds and analogues thereof BIOCRYST PHARMACEUTICALS, INC. (US) 2025-12-02 US disclosed
US-12472165-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (VG) 2025-11-18 US disclosed
US-20250332148-A1 RILUZOLE PRODRUGS AND THEIR USE BIOHAVEN THERAPEUTICS LTD (US) 2025-10-30 US disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
US-12295942-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (VG) 2025-05-13 US disclosed
US-12213965-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (VG) 2025-02-04 US disclosed
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-12-05 US disclosed
US-12005046-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (US) 2024-06-11 US disclosed
EP-2900642-A1 SUBSTITUTED SULFONAMIDE COMPOUNDS F. Hoffmann-La Roche AG (CH) 2015-08-05 EP disclosed
US-20150197509-A1 SUBSTITUTED SULFONAMIDE SOLUTIONS GENENTECH, INC. (US) 2015-07-16 US disclosed
WO-2015097461-A1 PRODRUG COMPOUNDS PROXIMAGEN LIMITED (GB) 2015-07-02 WO disclosed
EP-2870148-A1 PRO-DRUG COMPOUNDS Proximagen Limited (GB) 2015-05-13 EP disclosed
US-20140011773-A1 Pro-drug Compounds PROXIMAGEN LIMITED (GB) 2014-01-09 US disclosed
WO-2014006407-A1 PRO-DRUG COMPOUNDS PROXIMAGEN LIMITED (GB) 2014-01-09 WO disclosed
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 US disclosed
US-20040014962-A1 1-Methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-22 US disclosed
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014962-A1 1-Methylcarbapenem derivatives CD14, CPT1A, ACMSD HDAC6 1185/4885HDAC1 370/4885HDAC2 1498/4885
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE IL6ST, GFRA3, GFRA1 HDAC6 562/4885HDAC1 325/4885HDAC2 715/4885
US-12485109-B2 Pyrrolo 12.3-dipyrimidine compounds and analogues thereof C5, DPYD, C9 HDAC6 2732/4885HDAC1 2304/4885HDAC2 3414/4885
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION KRAS, NRAS, HRAS HDAC6 4541/4885HDAC1 4641/4885HDAC2 4766/4885
US-12005046-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 HDAC6 477/4885HDAC1 145/4885HDAC2 536/4885
US-20150197509-A1 SUBSTITUTED SULFONAMIDE SOLUTIONS TRPA1, TRPV1, TRPV5 HDAC6 663/4885HDAC1 1305/4885HDAC2 1546/4885
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE GFRA3, IL6ST, GFRA1 HDAC6 566/4885HDAC1 328/4885HDAC2 747/4885
US-12472165-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 HDAC6 477/4885HDAC1 145/4885HDAC2 536/4885
US-12295942-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 HDAC6 477/4885HDAC1 145/4885HDAC2 536/4885
US-20250332148-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 HDAC6 477/4885HDAC1 145/4885HDAC2 536/4885
US-20140011773-A1 Pro-drug Compounds GJA1, GJB2, REN HDAC6 2538/4885HDAC1 2309/4885HDAC2 3196/4885
US-12213965-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 HDAC6 477/4885HDAC1 145/4885HDAC2 536/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS HDAC6 4541/4885HDAC1 4641/4885HDAC2 4766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.