SCHEMBL6016919

SCHEMBL6016919

O=C(OCCl)OC1CCOCC1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
KAT2B Q92831 1/20 0.33
BAZ2B Q9UIF8 1/20 0.33
HTT P42858 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12987688 0.93 L3MBTL1 (0.38) L3MBTL1KAT2BBAZ2BHTTEPHX1
SCHEMBL12986219 0.89 CTSL (0.36)
SCHEMBL12987219 0.89 CTSL (0.36)
SCHEMBL12986217 0.89 CTSL (0.36)
SCHEMBL12988069 0.86
SCHEMBL4690944 0.82 EPHX1 (0.46) L3MBTL1HTTEPHX1
SCHEMBL697265 0.82 EPHX1 (0.41) L3MBTL1HTTEPHX1
SCHEMBL1023586 0.81 KAT2B (0.43) L3MBTL1KAT2BBAZ2BEPHX1
SCHEMBL305711 0.81 L3MBTL1 (0.35) L3MBTL1KAT2BBAZ2B
SCHEMBL1497921 0.81 L3MBTL1 (0.35) L3MBTL1KAT2BBAZ2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2903979-B1 NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES INHIBIKASE THERAPEUTICS INC (US) 2020-08-19 EP claimed
US-9907796-B2 Methods of treating tumoral diseases, or bacterial or viral infections INHIBIKASE THERAPEUTICS, INC. (US) 2018-03-06 US claimed
US-20170000789-A1 Methods of Treating Tumoral Diseases, or Bacterial or Viral Infections SPHAERA PHARMA PTE. LTD. (SG) 2017-01-05 US claimed
US-9487500-B2 Compounds and compositions thereof INHIBIKASE THERAPEUTICS, INC. (US) 2016-11-08 US claimed
US-9359376-B2 Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds SPHAERA PHARMA PTE. LTD (SG) 2016-06-07 US claimed
EP-2903979-A1 NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES Inhibikase Therapeutics, Inc. (US) 2015-08-12 EP claimed
US-20140121367-A1 SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS PIVOT HOLDING LLC 2014-05-01 US claimed
US-20140100225-A1 NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES INHIBIKASE THERAPEUTICS, INC. (US) 2014-04-10 US claimed
WO-2014055938-A1 NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES INHIBIKASE THERAPEUTICS, INC. (US) 2014-04-10 WO claimed
EP-2693876-A1 SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS Sphaera Pharma Pte. Ltd (SG) 2014-02-12 EP claimed
WO-2012137225-A1 SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS SPHAERA PHARMA PVT. LTD (IN) 2012-10-11 WO claimed
US-12629371-B2 Compositions and methods for inhibiting kinases INHIBIKASE THERAPEUTICS, INC. (US) 2026-05-19 US disclosed
EP-3882252-B1 BETA-LACTAMASE INHIBITORS VENATORX PHARMACEUTICALS INC (US) 2025-11-19 EP disclosed
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
US-20250011344-A1 PRODRUGS AND DERIVATIVES OF PSILOCIN AND USES THEREOF TERRAN BIOSCIENCES INC (US) 2025-01-09 US disclosed
WO-2012137225-A1 SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS SPHAERA PHARMA PVT. LTD (IN) 2012-10-11 WO disclosed
US-20110288054-A1 COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS SCHERING CORPORATION (US) 2011-11-24 US disclosed
EP-1636240-A1 BETA-LACTAMASE INHIBITOR PRODRUG Pfizer Products Inc. (US) 2006-03-22 EP disclosed
US-20050004093-A1 Beta-lactamase inhibitor prodrug PFIZER INC 2005-01-06 US disclosed
WO-2004108733-A1 BETA-LACTAMASE INHIBITOR PRODRUG PFIZER PRODUCTS INC. (US) 2004-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004093-A1 Beta-lactamase inhibitor prodrug SI, CMBL, STS L3MBTL1 83/4885KAT2B 3976/4885BAZ2B 3338/4885
US-20140121367-A1 SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS TPMT, BHMT2, PFAS L3MBTL1 4514/4885KAT2B 2167/4885BAZ2B 2420/4885
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A L3MBTL1 2580/4885KAT2B 992/4885BAZ2B 619/4885
US-20170000789-A1 Methods of Treating Tumoral Diseases, or Bacterial or Viral Infections POLI, RNASE1, VHL L3MBTL1 986/4885KAT2B 1701/4885BAZ2B 1151/4885
US-12629371-B2 Compositions and methods for inhibiting kinases PTK2, HCK, PTK2B L3MBTL1 3508/4885KAT2B 3059/4885BAZ2B 2276/4885
US-20140100225-A1 NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES POLI, MCL1, HRAS L3MBTL1 1400/4885KAT2B 2532/4885BAZ2B 320/4885
US-20250011344-A1 PRODRUGS AND DERIVATIVES OF PSILOCIN AND USES THEREOF PSAP, PIGO, PSAT1 L3MBTL1 440/4885KAT2B 4564/4885BAZ2B 4359/4885
US-20110288054-A1 COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS ADAMTS1, ADAMTS13, ADAMTS7 L3MBTL1 4828/4885KAT2B 1688/4885BAZ2B 2810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.