Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.46 |
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.41 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.38 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL8489528 | 0.96 | P2RY12 (0.42) | P2RY12TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL7098523 | 0.84 | L3MBTL1 (0.45) | P2RY12TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL29575161 | 0.83 | TSHR (0.44) | P2RY12TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL10487048 | 0.83 | TSHR (0.44) | P2RY12TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL14576109 | 0.79 | PTGS1 (0.60) | P2RY12TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL28660366 | 0.79 | L3MBTL1 (0.50) | P2RY12TSHRALDH1A1NPC1RAB9A | |
| Potassium Ion SCHEMBL7752290 | 0.78 | TSHR (0.44) | P2RY12TSHRALDH1A1CYP3A4TDP1 | |
| Lithium Ion SCHEMBL28830257 | 0.78 | TSHR (0.44) | P2RY12TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL3396550 | 0.78 | L3MBTL1 (0.44) | P2RY12TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL29386214 | 0.78 | L3MBTL1 (0.44) | P2RY12TSHRALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785362-B2 | Triazine derivative dye transfer inhibitors, washing products containing the same and uses therefor | HENKEL AG & CO. KGAA (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8263541-B2 | comprising a dye transfer inhibitor selected from triazine derivatives such as N,N'-bis-[2-chloro-4(sulfonaphth-1-yl-amino)-triazin-6-yl]-1,2-diaminoethane, optionally mixed with polymers and an aqueous solution of surfactants; colorfastness | HENKEL AG & CO. KGAA (DE) | 2012-09-11 | — | — | US | disclosed |
| US-20120196785-A1 | TRIAZINE DERIVATIVE DYE TRANSFER INHIBITORS, WASHING PRODUCTS CONTAINING THE SAME AND USES THEREFOR | HENKEL AG & CO. KGAA (DE) | 2012-08-02 | — | — | US | disclosed |
| US-20120040881-A1 | GRAYING-INHIBITING WASHING AGENT | Henkel AG & KGaA (DE) | 2012-02-16 | — | — | US | disclosed |
| EP-1457511-B1 | CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME | MITSUI CHEMICALS INC (JP) | 2009-07-15 | — | — | EP | disclosed |
| US-20080234167-A1 | Colour Protection Washing Product | HENKEL KGAA (DE) | 2008-09-25 | — | — | US | disclosed |
| US-7345135-B2 | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS, INC. (JP) | 2008-03-18 | — | — | US | disclosed |
| EP-1457511-A1 | CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME | Mitsui Chemicals, Inc. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-0254294-B1 | METHOD OF PROCESSING A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL AND A COLOR DEVELOPER | FUJI PHOTO FILM CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-5064751-A | Stability, antifogging | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| EP-0254294-A2 | Method of processing a silver halide color photographic material and a color developer | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |
| US-4122088-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4119784-A | Anionic substituted sulfonamido biphenyls | AMERICAN CYANAMID COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4107202-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040881-A1 | GRAYING-INHIBITING WASHING AGENT | WASHC5, GYPA, ACHE | P2RY12 3292/4885PPARG 1129/4885CA12 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.