Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | RECQL | P46063 | 2/20 | 0.75 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.75 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | F3 | P13726 | 2/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | GSK3B | P49841 | 6/20 | 0.71 |
| ▸ | BACE1 | P56817 | 6/20 | 0.71 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.71 |
| ▸ | FOS | P01100 | 2/20 | 0.69 |
| ▸ | JUN | P05412 | 2/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4295439 | 1.00 | MAPT (0.75) | MAPTPLIN1LMNARECQLPLIN5 | |
| SCHEMBL608387 | 1.00 | MAPT (0.75) | MAPTPLIN1LMNARECQLPLIN5 | |
| SCHEMBL13311574 | 0.91 | GSK3B (0.89) | MAPTPLIN1LMNARECQLPLIN5 | |
| SCHEMBL28435740 | 0.86 | MAPT (1.00) | MAPTPLIN1LMNARECQLPLIN5 | |
| SCHEMBL22146 | 0.86 | MAPT (1.00) | MAPTPLIN1LMNARECQLPLIN5 | |
| SCHEMBL478244 | 0.86 | MAPT (1.00) | MAPTPLIN1LMNARECQLPLIN5 | |
| SCHEMBL20846 | 0.86 | MAPT (1.00) | MAPTPLIN1LMNARECQLPLIN5 | |
| SCHEMBL20856054 | 0.86 | MAPT (1.00) | MAPTPLIN1LMNARECQLPLIN5 | |
| SCHEMBL20518814 | 0.86 | MAPT (1.00) | MAPTPLIN1LMNARECQLPLIN5 | |
| SCHEMBL28181 | 0.86 | MAPT (1.00) | MAPTPLIN1LMNARECQLPLIN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190720-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS | KAHRS, Bjoern Colin (CH) | 2023-06-22 | — | — | US | disclosed |
| US-20230190720-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS | KAHRS, Bjoern Colin (CH) | 2023-06-22 | — | — | US | disclosed |
| US-20230190856-A1 | COMPOSITION COMPRISING A COMPLEX COMPRISING A CURCUMINOID COMPOUND, AND STEVIOL GLYCOSIDES OR A LICORICE EXTRACT OR A FRACTION THEREOF, AND USES THEREOF | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2023-06-22 | — | — | US | disclosed |
| US-20230190856-A1 | COMPOSITION COMPRISING A COMPLEX COMPRISING A CURCUMINOID COMPOUND, AND STEVIOL GLYCOSIDES OR A LICORICE EXTRACT OR A FRACTION THEREOF, AND USES THEREOF | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2023-06-22 | — | — | US | disclosed |
| US-20230000940-A1 | Composition for prevention or treatment of Porcine epidemic diarrhea virus infection comprising curcuminoid and licorice extracts or fraction thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2023-01-05 | — | — | US | disclosed |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2022-05-19 | — | — | US | disclosed |
| US-20210322346-A1 | CHEMICALLY MODIFIED CURCUMINS FOR USE IN THE PRODUCTION OF LIPOXINS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-10-21 | — | — | US | disclosed |
| US-20200383958-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2020-12-10 | — | — | US | disclosed |
| US-10751330-B2 | Human therapeutic agents | ANKH LIFE SCIENCES LIMITED (IE) | 2020-08-25 | — | — | US | disclosed |
| US-10744124-B2 | Human therapeutic agents | ANKH LIFE SCIENCES LIMITED (IE) | 2020-08-18 | — | — | US | disclosed |
| US-7682636-B2 | Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2 | METAPROTEOMICS, LLC (US) | 2010-03-23 | — | — | US | disclosed |
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2009-10-22 | — | — | US | disclosed |
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2009-10-22 | — | — | US | disclosed |
| US-20090263522-A1 | Curcuminoid Compositions Exhibiting Synergistic Inhibition Of The Expression And/Or Activity Of Cyclooxygenase-2 | META PROTEOMICS, LLC | 2009-10-22 | — | — | US | disclosed |
| US-7572829-B2 | Pharmaceutical compositions useful in prevention and treatment of Beta-amyloid protein-induced disease | KIM DARRICK S H L | 2009-08-11 | — | — | US | disclosed |
| US-20080085932-A1 | Pharmaceutical Compositions Useful In Prevention and Treatment of Beta-Amyloid Protein-Induced Disease | KIM DARRICK S | 2008-04-10 | — | — | US | disclosed |
| US-20070141183-A1 | Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2 | METAPROTEOMICS, LLC (CA) | 2007-06-21 | — | — | US | disclosed |
| US-20070060644-A1 | Therapeutic curcumin derivatives | STC.UNM | 2007-03-15 | — | — | US | disclosed |
| US-20070060644-A1 | Therapeutic curcumin derivatives | STC.UNM | 2007-03-15 | — | — | US | disclosed |
| US-20070003641-A1 | Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease | KIM DARRICK S H | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10744124-B2 | Human therapeutic agents | INMT, HNMT, HASPIN | MAPT 497/4885PLIN1 707/4885LMNA 1880/4885 |
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | CHAT, SLC18A3, GAP43 | MAPT 30/4885PLIN1 2647/4885LMNA 3574/4885 |
| US-20070003641-A1 | Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease | APP, BACE1, GSAP | MAPT 76/4885PLIN1 891/4885LMNA 765/4885 |
| US-20230190856-A1 | COMPOSITION COMPRISING A COMPLEX COMPRISING A CURCUMINOID COMPOUND, AND STEVIOL GLYCOSIDES OR A LICORICE EXTRACT OR A FRACTION THEREOF, AND USES THEREOF | CD4, IFNG, CD14 | MAPT 2185/4885PLIN1 3516/4885LMNA 2751/4885 |
| US-20070060644-A1 | Therapeutic curcumin derivatives | FABP2, GLS2, FABP1 | MAPT 448/4885PLIN1 230/4885LMNA 1060/4885 |
| US-10751330-B2 | Human therapeutic agents | INMT, HNMT, HASPIN | MAPT 497/4885PLIN1 707/4885LMNA 1880/4885 |
| US-20080085932-A1 | Pharmaceutical Compositions Useful In Prevention and Treatment of Beta-Amyloid Protein-Induced Disease | APP, BACE1, PSEN1 | MAPT 8/4885PLIN1 802/4885LMNA 1968/4885 |
| US-20230000940-A1 | Composition for prevention or treatment of Porcine epidemic diarrhea virus infection comprising curcuminoid and licorice extracts or fraction thereof | CUL3, PIGS, PYCARD | MAPT 502/4885PLIN1 48/4885LMNA 2124/4885 |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | MAPT 497/4885PLIN1 707/4885LMNA 1880/4885 |
| US-20200383958-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | MAPT 497/4885PLIN1 707/4885LMNA 1880/4885 |
| US-20230190720-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS | PPARG, PPARA, PPARD | MAPT 1063/4885PLIN1 2353/4885LMNA 3371/4885 |
| US-20210322346-A1 | CHEMICALLY MODIFIED CURCUMINS FOR USE IN THE PRODUCTION OF LIPOXINS | ALOX15B, ALOX15, ALOX12 | MAPT 4483/4885PLIN1 9/4885LMNA 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.