Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175974 | 0.78 | FFAR4 (0.38) | — | |
| SCHEMBL705727 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL1448228 | 0.72 | TPMT (0.54) | TPMT | |
| SCHEMBL2513559 | 0.72 | ALOX15 (0.36) | TPMT | |
| SCHEMBL3652199 | 0.70 | CTRC (0.47) | — | |
| SCHEMBL6160721 | 0.70 | DHODH (0.37) | — | |
| SCHEMBL2955024 | 0.68 | XDH (0.35) | — | |
| SCHEMBL3713101 | 0.68 | CES2 (0.41) | TPMT | |
| SCHEMBL3653446 | 0.67 | MARS1 (0.49) | — | |
| SCHEMBL3650607 | 0.67 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834510-B1 | Flavone derivative and medicine comprising the same | KOWA CO (JP) | 2005-02-23 | — | — | EP | disclosed |
| EP-0902007-B1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2003-11-05 | — | — | EP | disclosed |
| US-6136848-A | ANTIALLERGENS; ASTHMA THERAPY | KOWA CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-6046212-A | ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0902007-A1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |
| EP-0834510-A2 | Flavone derivative and medicine comprising the same | KOWA CO. LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |