Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30655553 | 1.00 | ALDH1A1 (0.71) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL7176501 | 0.88 | ALDH1A1 (0.65) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL6774685 | 0.86 | ALDH1A1 (0.73) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL5861624 | 0.85 | ALDH1A1 (0.71) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL6295221 | 0.85 | ALDH1A1 (0.71) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL589164 | 0.84 | ALDH1A1 (0.74) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL27395266 | 0.84 | ALDH1A1 (1.00) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL6775301 | 0.84 | ALDH1A1 (0.70) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL7192519 | 0.82 | ALDH1A1 (0.68) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL9123805 | 0.82 | ALDH1A1 (0.64) | ALDH1A1RECQLPKMKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869352-B | Chemical compound | 诺瑟拉有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-3596052-B1 | CHEMICAL COMPOUNDS | NODTHERA LTD (GB) | 2022-07-20 | — | — | EP | disclosed |
| US-11345669-B2 | Urea derivatives and methods of use thereof | NodThera Limited (GB) | 2022-05-31 | — | — | US | disclosed |
| US-11345669-B2 | Urea derivatives and methods of use thereof | NodThera Limited (GB) | 2022-05-31 | — | — | US | disclosed |
| US-20200131141-A1 | CHEMICAL COMPOUNDS | NodThera Limited (GB) | 2020-04-30 | — | — | US | disclosed |
| US-20200131141-A1 | CHEMICAL COMPOUNDS | NodThera Limited (GB) | 2020-04-30 | — | — | US | disclosed |
| CN-110869352-A | Chemical compound | 诺瑟拉有限公司 | 2020-03-06 | — | — | CN | disclosed |
| WO-2018167468-A1 | CHEMICAL COMPOUNDS | NodThera Limited (GB) | 2018-09-20 | — | — | WO | disclosed |
| EP-2796546-B1 | Incorporation of unnatural amino acids | SCRIPPS RESEARCH INST (US) | 2017-08-09 | — | — | EP | disclosed |
| EP-1490483-B1 | IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | SCRIPPS RESEARCH INST (US) | 2015-06-03 | — | — | EP | disclosed |
| US-20090068717-A1 | In vivo incorporation of unnatural amino acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| US-20080261311-A1 | Translation systems with orthogonal aminoacyl tRNA synthetase; membrane proteins | THE SCRIPPS RESEARCH INSTITUTE and THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-10-23 | — | — | US | disclosed |
| US-20080227152-A1 | Translation systems with orthogonal aminoacyl tRNA synthetase; membrane proteins | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-18 | — | — | US | disclosed |
| US-20080167243-A1 | immunizing a subject with a sufficient amount of a translated polypeptide to produce antibody; containing a phenylalanine or tyrosine derivative analoges | THE SCRIPPS RESEARCH INSTITUTE | 2008-07-10 | — | — | US | disclosed |
| US-20080166783-A1 | Translation system for biosynthesis of insulin like growth factor | THE SCRIPPS RESEARCH INSTITUTE and THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-07-10 | — | — | US | disclosed |
| US-7368275-B2 | Orthogonal tRNA synthetase that aminoacylates with reduced efficiency; lower km and recognizes selector codon in mRNA | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-05-06 | — | — | US | disclosed |
| US-20070117184-A1 | Translation systems with orthogonal aminoacyl tRNA synthetase; membrane proteins | THE SCRIPPS RESEARCH INSTITUTE | 2007-05-24 | — | — | US | disclosed |
| US-7045337-B2 | Translation system for use in the generation of protein containing adjusted amino acid sequences | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-16 | — | — | US | disclosed |
| US-20050250183-A1 | In vivo incorporation of unnatural amino acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-11-10 | — | — | US | disclosed |
| US-20030082575-A1 | Translation system for use in the generation of protein containing adjusted amino acid sequences | THE SCRIPPS RESEARCH INSTITUTE (US) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167243-A1 | immunizing a subject with a sufficient amount of a translated polypeptide to produce antibody; containing a phenylalanine or tyrosine derivative analoges | DNPEP, NPEPPS, TYR | ALDH1A1 4657/4885RECQL 4710/4885PKM 1283/4885 |
| US-20050250183-A1 | In vivo incorporation of unnatural amino acids | BCAT1, AADAT, NPEPPS | ALDH1A1 3231/4885RECQL 4767/4885PKM 2702/4885 |
| US-20200131141-A1 | CHEMICAL COMPOUNDS | IL1B, CASP1, IL1A | ALDH1A1 325/4885RECQL 799/4885PKM 3140/4885 |
| US-20080261311-A1 | Translation systems with orthogonal aminoacyl tRNA synthetase; membrane proteins | AARS1, NSUN3, TRMT1 | ALDH1A1 4462/4885RECQL 3742/4885PKM 3459/4885 |
| US-11345669-B2 | Urea derivatives and methods of use thereof | IL1B, IL1A, NOD1 | ALDH1A1 397/4885RECQL 429/4885PKM 2439/4885 |
| US-20070117184-A1 | Translation systems with orthogonal aminoacyl tRNA synthetase; membrane proteins | AARS1, NSUN3, TRMT1 | ALDH1A1 4462/4885RECQL 3742/4885PKM 3459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.