Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64057 | 0.93 | PPARG (0.39) | L3MBTL1KDM4ELMNALTA4HUSP30 | |
| SCHEMBL65686 | 0.86 | PDK1 (0.38) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL65232 | 0.82 | TMEM97 (0.37) | USP30PDK1PDK2PDK3PDK4 | |
| SCHEMBL64233 | 0.80 | CHRM5 (0.35) | L3MBTL1KDM4ELMNACYP3A4LTA4H | |
| SCHEMBL78724 | 0.80 | KDM4E (0.34) | L3MBTL1KDM4ELMNAMAPTCHRM5 | |
| SCHEMBL64503 | 0.78 | PPARA (0.33) | KDM4ELMNACYP3A4CHRM5CHRM1 | |
| SCHEMBL78725 | 0.77 | KDM4E (0.34) | L3MBTL1KDM4ELMNALTA4HPDK1 | |
| SCHEMBL78781 | 0.76 | KDM4E (0.36) | L3MBTL1KDM4ELMNALTA4HCHRM2 | |
| SCHEMBL80037 | 0.76 | ITGB3 (0.32) | KDM4ELMNA | |
| SCHEMBL65299 | 0.75 | LTA4H (0.35) | L3MBTL1KDM4EKCNH2RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |