SCHEMBL6448558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24268493	0.88	ALDH1A1 (0.41)	ALDH1A1HSD11B1GAAL3MBTL1LMNA
	SCHEMBL6448357	0.88	—	—
	SCHEMBL12912768	0.87	ALDH1A1 (0.48)	ALDH1A1GAAL3MBTL1LMNAABL1
	SCHEMBL24409143	0.87	PKM (0.35)	ALDH1A1GAAL3MBTL1LMNANPSR1
	SCHEMBL14479483	0.86	PRKCA (0.42)	ALDH1A1GAANPSR1PRKCA
	SCHEMBL17578294	0.86	PRKCA (0.42)	ALDH1A1GAANPSR1PRKCA
	SCHEMBL75500	0.86	PRKCA (0.42)	ALDH1A1GAANPSR1PRKCA
	SCHEMBL26059431	0.86	L3MBTL1 (0.40)	ALDH1A1HSD11B1GAAL3MBTL1LMNA
	SCHEMBL17195513	0.86	NPSR1 (0.36)	LMNANPSR1PRKCASMN1; SMN2
	SCHEMBL24413589	0.86	NPSR1 (0.36)	ALDH1A1HSD11B1LMNAABL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.