Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 7/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502583 | 0.87 | LMNA (0.48) | HTR6DRD3DRD2HTR2AHTR2C | |
| SCHEMBL6510748 | 0.87 | HTR6 (0.46) | HTR6DRD3DRD2HTR2AHTR2C | |
| SCHEMBL6500880 | 0.87 | LMNA (0.51) | HTR6DRD3DRD2MAPTGAA | |
| SCHEMBL6504564 | 0.86 | HTR6 (0.54) | HTR6DRD3DRD2HTR2AHTR2C | |
| SCHEMBL6509242 | 0.86 | MAOB (0.54) | HTR6HTR2AHTR2CMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6504357 | 0.85 | MAOB (0.53) | HTR6HTR2AHTR2CMAPTKDM4E | |
| SCHEMBL6508620 | 0.83 | MAPT (0.49) | HTR6DRD3DRD2HTR2AHTR2C | |
| SCHEMBL6507562 | 0.83 | MAPT (0.57) | HTR6DRD2MAPTCA1CA2 | |
| SCHEMBL6511504 | 0.83 | DRD2 (0.52) | DRD3DRD2MAPTGAAALDH1A1 | |
| SCHEMBL6508601 | 0.83 | TNF (0.48) | TNFNOD1NOD2MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |