Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502583 | 0.87 | LMNA (0.48) | MAPTALDH1A1POLBNPSR1LMNA | |
| SCHEMBL6510748 | 0.87 | HTR6 (0.46) | ALDH1A1KMT2APOLB | |
| SCHEMBL6500880 | 0.87 | LMNA (0.51) | MAPTGAAALDH1A1KMT2APOLB | |
| SCHEMBL6509242 | 0.86 | MAOB (0.54) | MAPTKMT2ALMNATSHR | |
| SCHEMBL6504564 | 0.86 | HTR6 (0.54) | MAPTGAALMNATSHR | |
| Hydrochloric Acid SCHEMBL6504357 | 0.85 | MAOB (0.53) | MAPTKMT2ALMNATSHR | |
| SCHEMBL6507562 | 0.83 | MAPT (0.57) | MAPTALDH1A1KMT2APOLBCA1 | |
| SCHEMBL6508620 | 0.83 | MAPT (0.49) | MAPTRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL6511504 | 0.83 | DRD2 (0.52) | MAPTGAAALDH1A1KMT2APOLB | |
| SCHEMBL6499030 | 0.83 | TNF (0.46) | TNFNOD2NOD1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |