Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65299 | 0.92 | LTA4H (0.35) | LTA4HALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL64035 | 0.79 | SLC6A2 (0.37) | TSHRNPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL64057 | 0.76 | PPARG (0.39) | PPARGPPARAPPARDLTA4HTSHR | |
| SCHEMBL66855 | 0.76 | ELANE (0.38) | — | |
| SCHEMBL65813 | 0.75 | PPARG (0.40) | PPARGPPARAPPARDLTA4HALDH1A1 | |
| SCHEMBL64056 | 0.70 | PPARG (0.38) | PPARGPPARAPPARDALDH1A1TSHR | |
| SCHEMBL64234 | 0.69 | L3MBTL1 (0.36) | LTA4HL3MBTL1MAPTEGFRKDM4E | |
| SCHEMBL15951884 | 0.68 | RIPK1 (0.36) | HRH3 | |
| SCHEMBL78854 | 0.68 | PPARG (0.40) | PPARGPPARAPPARDALDH1A1TSHR | |
| SCHEMBL66293 | 0.67 | PPM1B (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |