Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892910 | 0.84 | USP2 (0.30) | — | |
| SCHEMBL5946667 | 0.77 | CA4 (0.34) | CA4 | |
| SCHEMBL7513032 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL4539299 | 0.71 | — | — | |
| SCHEMBL892908 | 0.71 | — | — | |
| SCHEMBL893127 | 0.70 | USP2 (0.31) | — | |
| SCHEMBL6899580 | 0.68 | CA4 (0.40) | CA4 | |
| SCHEMBL2441480 | 0.67 | CA2 (0.38) | CA4 | |
| SCHEMBL5385256 | 0.65 | USP2 (0.33) | — | |
| Lithium Ion SCHEMBL5013299 | 0.64 | CA4 (0.35) | CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677112-B2 | CONTAINING COMPOUND A (MERCAPTO TETRAZOLE COMPOUND) HAVING ADSORPTIVITY TO SILVER, CONTENT OF COMPOUND A IN THE SHELL IS SMALLER THAN THE CONTENT OF COMPOUND A IN THE CORE | KONICA CORPORATION (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030203328-A1 | Silver halide emulsion, preparation method of silver halide emulsion, silver halide light-sensitive photographic material, silver halide light-sensitive color photographic material, and image forming method | KONICA CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |
| EP-1327907-A2 | Silver halide emulsion, preparation method of silver halide emulsion, silver halide light-sensitive photographic material, silver halide light-sensitive color photographic material, and image forming method | KONICA CORPORATION (JP) | 2003-07-16 | — | — | EP | disclosed |