Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.33 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.33 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.33 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | DUSP5 | Q16690 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | FABP3 | P05413 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 2/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850302 | 0.79 | TDP1 (0.47) | LMNATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL67964 | 0.79 | ALDH1A1 (0.50) | LMNATDP1ALDH1A1MAPTKDM4E | |
| Sulfuric Acid SCHEMBL8078542 | 0.78 | LMNA (0.46) | LMNATDP1DUSP5PTPN1FABP3 | |
| SCHEMBL11042085 | 0.78 | FABP4 (0.45) | LMNAFABP3FABP4FABP5ALDH1A1 | |
| Sulfuric Acid SCHEMBL30910258 | 0.78 | FABP4 (0.60) | LMNATDP1FABP3FABP4FABP5 | |
| Sulfuric Acid SCHEMBL8103454 | 0.77 | ALDH1A1 (0.48) | LMNATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL8406672 | 0.77 | ALDH1A1 (0.48) | LMNATDP1ALDH1A1MAPTKDM4E | |
| Hydrogen Peroxide SCHEMBL11036237 | 0.76 | LMNA (0.47) | LMNATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL14062504 | 0.74 | FABP4 (0.42) | LMNATDP1FABP3FABP4FABP5 | |
| SCHEMBL5153019 | 0.74 | ALDH1A1 (0.50) | LMNATDP1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624033-A | Ligand compound, iron/nickel complex, catalyst, preparation method and application thereof | 中国科学技术大学 | 2024-03-01 | — | — | CN | disclosed |
| US-20040224874-A1 | Process for producing coated detergent particles | JAGANNATH GIRISH (JP) | 2004-11-11 | — | — | US | disclosed |
| US-6767882-B1 | COATING DETERGENT GRANULES IN MIXER WITH SOLUTION OF WATER SOLUBLE SODIUM LINEAR ALKYLBENZENESULFONATE AND/OR HYDROPHOBIC SECONDARY ALKYL SULFATE ANIONIC SURFACTANT AND SODIUM XYLENE SULFONATE AND/OR ALKYLDIPHENYLOXIDE DISULFONATE HYDROTROPE | THE PROCTER & GAMBLE COMPANY | 2004-07-27 | — | — | US | disclosed |
| EP-1187902-A1 | PROCESS FOR PRODUCING COATED DETERGENT PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000078909-A1 | PROCESS FOR PRODUCING COATED DETERGENT PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |