Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 10/20 | 0.43 |
| ▸ | CA2 known ✓ | P00918 | 10/20 | 0.43 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.38 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.36 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL17456604 | 0.96 | TSHR (0.59) | TSHRHPGDRECQLGLAMAPK1 | |
| Potassium Ion SCHEMBL12485367 | 0.96 | TSHR (0.59) | TSHRHPGDRECQLGLAMAPK1 | |
| SCHEMBL9186645 | 0.96 | TSHR (0.59) | TSHRHPGDRECQLGLAMAPK1 | |
| SCHEMBL2568777 | 0.94 | TSHR (0.74) | TSHRHPGDRECQLGLAMAPK1 | |
| SCHEMBL2729998 | 0.92 | RECQL (0.78) | TSHRHPGDRECQLGLAMAPK1 | |
| SCHEMBL2730477 | 0.92 | RECQL (0.78) | TSHRHPGDRECQLGLAMAPK1 | |
| SCHEMBL818230 | 0.92 | RECQL (0.78) | TSHRHPGDRECQLGLAMAPK1 | |
| SCHEMBL818842 | 0.92 | RECQL (0.78) | TSHRHPGDRECQLGLAMAPK1 | |
| SCHEMBL15206914 | 0.92 | RECQL (0.78) | TSHRHPGDRECQLGLAMAPK1 | |
| SCHEMBL10765886 | 0.92 | RECQL (0.78) | TSHRHPGDRECQLGLAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049674-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE | L'OREAL (FR) | 2025-02-13 | — | — | US | claimed |
| US-20240423888-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF | L'OREAL (FR) | 2024-12-26 | — | — | US | claimed |
| CN-118871078-A | Cosmetic or dermatological composition comprising at least a merocyanine and a hydrotrope | 欧莱雅 | 2024-10-29 | — | — | CN | claimed |
| EP-4447895-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF | L'OREAL (FR) | 2024-10-23 | — | — | EP | claimed |
| CN-118804735-A | Cosmetic and/or dermatological composition comprising at least one merocyanine and at least ascorbic acid and/or derivatives thereof | 莱雅公司 | 2024-10-18 | — | — | CN | claimed |
| WO-2023110763-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF | L'OREAL (FR) | 2023-06-22 | — | — | WO | claimed |
| US-9585893-B2 | Flumazenil complexes, compositions comprising same and uses thereof | COERULEUS LTD. (IL) | 2017-03-07 | — | — | US | claimed |
| US-20130345202-A1 | Flumazenil Complexes, Compositions Comprising Same And Uses Thereof | COERULEUS LTD. (IL) | 2013-12-26 | — | — | US | claimed |
| WO-2012114342-A1 | FLUMAZENIL COMPLEXES, COMPOSITIONS COMPRISING SAME AND USES THEREOF | COERULEUS LTD. (IL) | 2012-08-30 | — | — | WO | claimed |
| EP-0051232-B1 | HAND CLEANER | Henkel Kommanditgesellschaft auf Aktien (DE) | 1984-09-19 | — | — | EP | claimed |
| US-20250049674-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE | L'OREAL (FR) | 2025-02-13 | — | — | US | disclosed |
| US-20250049674-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE | L'OREAL (FR) | 2025-02-13 | — | — | US | disclosed |
| US-20250025393-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND DIPROPYLENE GLYCOL | L'OREAL (FR) | 2025-01-23 | — | — | US | disclosed |
| US-20250009625-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AT LEAST ONE DIOL COMPRISING FROM 4 TO 7 CARBON ATOMS | L'OREAL (FR) | 2025-01-09 | — | — | US | disclosed |
| US-20240423888-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF | L'OREAL (FR) | 2024-12-26 | — | — | US | disclosed |
| US-6087353-A | Phytosterol compositions and use thereof in foods, beverages, pharmaceuticals, nutraceuticals and the like | FORBES MEDI-TECH INC. (CA) | 2000-07-11 | — | — | US | disclosed |
| WO-2000015201-A2 | COMPOSITIONS COMPRISING ONE OR MORE PHYTOSTEROLS, PHYTOSTANOLS OR MIXTURES OF BOTH AND ONE OR MORE ALPHA, BETA, DELTA, OR GAMMA TOCOTRIENOLS OR DERIVATIVES THEREOF AND USE OF THE COMPOSITIONS IN TREATING OR PREVENTING CARDIOVASCULAR DISEASE, ITS UNDERLYING CONDITIONS AND OTHER DISORDERS | FORBES MEDI-TECH INC. (CA) | 2000-03-23 | — | — | WO | disclosed |
| WO-2000004887-A2 | COMPOSITIONS COMPRISING PHYTOSTEROL, PHYTOSTANOL OR MIXTURES OF BOTH AND OMEGA-3 FATTY ACIDS OR DERIVATIVES THEREOF AND USE OF THE COMPOSITION IN TREATING OR PREVENTING CARDIOVASCULAR DISEASE AND OTHER DISORDERS | FORBES MEDI-TECH INC. (CA) | 2000-02-03 | — | — | WO | disclosed |
| WO-1999063841-A1 | COMPOSITIONS COMPRISING PHYTOSTEROL AND/OR PHYTOSTANOL HAVING ENHANCED SOLUBILITY AND DISPERSABILITY | FORBES MEDI-TECH INC. (CA) | 1999-12-16 | — | — | WO | disclosed |
| WO-1999059421-A1 | ESTERIFIED AND SUBSEQUENTLY HYDROGENATED PHYTOSTEROL COMPOSITIONS AND USE THEREOF IN FOODS, BEVERAGES, PHARMACEUTICALS, NUTRACEUTICALS AND THE LIKE | FORBES MEDI-TECH INC. (CA) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250009625-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AT LEAST ONE DIOL COMPRISING FROM 4 TO 7 CARBON ATOMS | KRT18, DSC1, ECH1 | CA1 2303/4885CA2 1581/4885THRB 4382/4885 |
| US-20240423888-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF | KRT18, PROC, DSC1 | CA1 1327/4885CA2 797/4885THRB 4707/4885 |
| US-20250049674-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE | NAPRT, NAMPT, NNMT | CA1 440/4885CA2 393/4885THRB 4187/4885 |
| US-20250025393-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND DIPROPYLENE GLYCOL | KRT18, DSC1, DSG1 | CA1 1636/4885CA2 870/4885THRB 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.