SCHEMBL7158583

SCHEMBL7158583

CCCCc1ncc(C)nc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.37
PDE10A Q9Y233 3/20 0.35
NOS2 P35228 1/20 0.34
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33
GABRE P78334 1/20 0.33
GABRA6 Q16445 1/20 0.33
GABRG1 Q8N1C3 1/20 0.33
GABRG3 Q99928 1/20 0.33
GABRQ Q9UN88 1/20 0.33
KMT2A Q03164 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7115027 0.94 MEN1 (0.39) HRH3PDE10AKMT2AMEN1L3MBTL1
SCHEMBL7114777 0.92 KCNH2 (0.40) KMT2AMEN1L3MBTL1TDP1ALDH1A1
SCHEMBL2512668 0.92 KCNH2 (0.40) KMT2AMEN1L3MBTL1TDP1ALDH1A1
SCHEMBL29364752 0.88 HSP90AA1 (0.36) PDE10ANOS2ALDH1A1JAK3KDM4E
SCHEMBL7156533 0.88 HSP90AA1 (0.36) PDE10ANOS2ALDH1A1JAK3KDM4E
SCHEMBL10392527 0.84 HRH3 (0.37) HRH3PDE10ANOS2GABRPGABRD
SCHEMBL29365049 0.84 HRH3 (0.37) HRH3PDE10ANOS2GABRPGABRD
SCHEMBL31020874 0.79 TBXAS1 (0.33) JAK3KDM4E
SCHEMBL108874 0.79 JAK3 (0.35) PDE10AALDH1A1JAK3KDM4E
SCHEMBL29666109 0.79 JAK3 (0.35) PDE10AALDH1A1JAK3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365370-B2 Fragrance compositions THE PROCTER & GAMBLE COMPANY (US) 2022-06-21 US claimed
EP-3509647-B1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2020-10-21 EP claimed
US-9949911-B2 Antiperspirant and deodorant compositions THE PROCTER & GAMBLE COMPANY (US) 2018-04-24 US claimed
US-20170312204-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS PROCTER & GAMBLE (US) 2017-11-02 US claimed
US-20170267944-A1 FRAGRANCE COMPOSITIONS PROCTER & GAMBLE (US) 2017-09-21 US claimed
EP-3139902-A2 FRAGRANCE COMPOSITIONS The Procter & Gamble Company (US) 2017-03-15 EP claimed
US-20150322376-A1 Fragrance Compositions THE PROCTER & GAMBLE COMPANY 2015-11-12 US claimed
WO-2015171738-A2 FRAGRANCE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2015-11-12 WO claimed
EP-2931236-A2 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS The Procter & Gamble Company (US) 2015-10-21 EP claimed
EP-2931854-A1 FRAGRANCE MATERIALS The Procter & Gamble Company (US) 2015-10-21 EP claimed
EP-2931234-A2 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS The Procter and Gamble Company (US) 2015-10-21 EP claimed
CN-104902869-A Personal care compositions PROCTER & GAMBLE 2015-09-09 CN claimed
CN-104837973-A Fragrance materials PROCTER & GAMBLE 2015-08-12 CN claimed
US-20140179722-A1 Antiperspirant and Deodorant Compositions THE PROCTER & GAMBLE COMPANY (US) 2014-06-26 US claimed
US-20140170194-A1 FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 US claimed
US-20140170101-A1 Antiperspirant and Deodorant Compositions THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 US claimed
WO-2014093819-A2 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 WO claimed
WO-2014093807-A1 FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 WO claimed
WO-2014093747-A2 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 WO claimed
US-20260102294-A1 ABSORBENT ARTICLE COMPRISING A FRAGRANCE AND AN ODOR CONTROL COMPOSITION PROCTER & GAMBLE (US) 2026-04-16 US disclosed
US-12533269-B2 Absorbent article comprising a fragrance and an odor control composition THE PROCTER & GAMBLE COMPANY (US) 2026-01-27 US disclosed
US-12533302-B2 Systems and methods for delivery of actives and healing tissue VIAS PARTNERS, LLC 2026-01-27 US disclosed
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US disclosed
US-12350136-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US disclosed
US-12350135-B2 Absorbent article with odor control composition THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US disclosed
WO-2025047604-A1 ANIMAL OIL/FAT FLAVOR-IMPARTING AGENT 味の素株式会社 2025-03-06 WO disclosed
US-20240115437-A1 ABSORBENT ARTICLE COMPRISING A FRAGRANCE AND AN ODOR CONTROL COMPOSITION THE PROCTER & GAMBLE COMPANY 2024-04-11 US disclosed
US-11844854-B2 Fragrance materials THE PROCTER & GAMBLE COMPANY (US) 2023-12-19 US disclosed
EP-2775839-B1 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS UNIV CALIFORNIA (US) 2023-12-06 EP disclosed
US-11771864-B2 Devices, systems and methods for delivering coffee-derived volatiles Jorge Neval Moll Neto 2023-10-03 US disclosed
CN-116099087-A Device, system and method for delivering coffee derived volatiles 乔吉·内瓦尔·莫尔·内托 2023-05-12 CN disclosed
US-20230042590-A1 ABSORBENT ARTICLE WITH ODOR CONTROL COMPOSITION THE PROCTER & GAMBLE COMPANY 2023-02-09 US disclosed
US-20220401275-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2022-12-22 US disclosed
EP-3519026-B1 DEVICE FOR DELIVERING COFFEE-DERIVED VOLATILES MOLL NETO JORGE NEVAL (US) 2022-12-07 EP disclosed
US-11491099-B2 Antiperspirant and deodorant compositions THE PROCTER & GAMBLE COMPANY (US) 2022-11-08 US disclosed
CN-110022922-B Device, system and method for delivering coffee-derived volatiles 乔吉·内瓦尔·莫尔·内托 2022-10-28 CN disclosed
US-11458049-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2022-10-04 US disclosed
US-20220304902-A1 SYSTEMS AND METHODS FOR DELIVERY OF ACTIVES & HEALING TISSUE VIAS PARTNERS, LLC 2022-09-29 US disclosed
US-11365370-B2 Fragrance compositions THE PROCTER & GAMBLE COMPANY (US) 2022-06-21 US disclosed
CN-109568166-B Fragrance materials 宝洁公司 2022-01-28 CN disclosed
EP-3509561-B1 PERFUME COMPOSITIONS PROCTER & GAMBLE (US) 2021-07-21 EP disclosed
EP-3509562-B1 AEROSOL COMPOSITIONS PROCTER & GAMBLE (US) 2021-06-23 EP disclosed
US-20210177721-A1 FRAGRANCE MATERIALS PROCTER & GAMBLE (US) 2021-06-17 US disclosed
US-11000468-B2 Aerosol compositions THE PROCTER & GAMBLE COMPANY (US) 2021-05-11 US disclosed
US-10952951-B2 Fragrance materials THE PROCTER & GAMBLE COMPANY (US) 2021-03-23 US disclosed
EP-3509647-B1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2020-10-21 EP disclosed
EP-3290087-B1 SPRAY COMPOSITIONS, SPRAYABLE PRODUCTS, AND METHODS OF TREATING A SURFACE WITH THE SAME PROCTER & GAMBLE (US) 2020-10-14 EP disclosed
US-20200269009-A1 DEVICES, SYSTEMS AND METHODS FOR DELIVERING COFFEE-DERIVED VOLATILES Jorge Neval Moll Neto 2020-08-27 US disclosed
US-10688275-B2 Devices, systems and methods for delivering coffee-derived volatiles Jorge Neval Moll Neto (US) 2020-06-23 US disclosed
CN-104837973-B Fragrance materials 宝洁公司 2020-04-21 CN disclosed
US-20190292488-A1 PERFUME COMPOSITIONS PROCTER & GAMBLE (US) 2019-09-26 US disclosed
EP-3519026-A1 DEVICES, SYSTEMS AND METHODS FOR DELIVERING COFFEE-DERIVED VOLATILES Neto, Jorge Neval Moll (US) 2019-08-07 EP disclosed
EP-3509562-A1 AEROSOL COMPOSITIONS The Procter and Gamble Company (US) 2019-07-17 EP disclosed
EP-3509705-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS The Procter and Gamble Company (US) 2019-07-17 EP disclosed
EP-3509647-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS The Procter and Gamble Company (US) 2019-07-17 EP disclosed
EP-3509561-A1 PERFUME COMPOSITIONS The Procter and Gamble Company (US) 2019-07-17 EP disclosed
US-10351796-B2 Perfume compositions THE PROCTER & GAMBLE COMPANY (US) 2019-07-16 US disclosed
CN-110022922-A Device, system and method for delivering coffee-derived volatiles 乔吉·内瓦尔·莫尔·内托 2019-07-16 CN disclosed
CN-109568166-A Fragrance material 宝洁公司 2019-04-05 CN disclosed
US-20190070086-A1 FRAGRANCE MATERIALS PROCTER & GAMBLE (US) 2019-03-07 US disclosed
US-20180207074-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS PROCTER & GAMBLE (US) 2018-07-26 US disclosed
EP-2931234-B1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS PROCTER & GAMBLE (US) 2018-07-18 EP disclosed
US-9949911-B2 Antiperspirant and deodorant compositions THE PROCTER & GAMBLE COMPANY (US) 2018-04-24 US disclosed
WO-2018067579-A1 DEVICES, SYSTEMS AND METHODS FOR DELIVERING COFFEE-DERIVED VOLATILES NETO JORGE NEVAL MOLL (US) 2018-04-12 WO disclosed
US-20180093067-A1 DEVICES, SYSTEMS AND METHODS FOR DELIVERING COFFEE-DERIVED VOLATILES MOLL NETO, JORGE NEVAL 2018-04-05 US disclosed
WO-2018048718-A1 AEROSOL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2018-03-15 WO disclosed
WO-2018048717-A1 PERFUME COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2018-03-15 WO disclosed
WO-2018048852-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS THE PROCTER & GAMBLE COMPANY (US) 2018-03-15 WO disclosed
WO-2018048719-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2018-03-15 WO disclosed
US-20180064623-A1 AEROSOL COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-03-08 US disclosed
US-20180066206-A1 SPRAY COMPOSITIONS, SPRAYABLE PRODUCTS, AND METHODS OF TREATING A SURFACE WITH THE SAME THE PROCTER & GAMBLE COMPANY 2018-03-08 US disclosed
US-20180066207-A1 PERFUME COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-03-08 US disclosed
US-20180064588-A1 Absorbent Articles Including Perfume and Cyclodextrins THE PROCTER & GAMBLE COMPANY 2018-03-08 US disclosed
US-20180064624-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-03-08 US disclosed
EP-3290087-A1 SPRAY COMPOSITIONS, SPRAYABLE PRODUCTS, AND METHODS OF TREATING A SURFACE WITH THE SAME The Procter & Gamble Company (US) 2018-03-07 EP disclosed
US-20170312204-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS PROCTER & GAMBLE (US) 2017-11-02 US disclosed
US-20170267944-A1 FRAGRANCE COMPOSITIONS PROCTER & GAMBLE (US) 2017-09-21 US disclosed
US-20170233679-A1 FRAGRANCE MATERIALS PROCTER & GAMBLE (US) 2017-08-17 US disclosed
US-9730878-B2 Antiperspirant and deodorant compositions THE PROCTER & GAMBLE COMPANY (US) 2017-08-15 US disclosed
CN-106999973-A System and method for discharging edible material 阿甘芳香和精细化工有限公司 2017-08-01 CN disclosed
US-9708568-B2 Fragrance compositions THE PROCTER & GAMBLE COMPANY (US) 2017-07-18 US disclosed
EP-3139902-A2 FRAGRANCE COMPOSITIONS The Procter & Gamble Company (US) 2017-03-15 EP disclosed
US-20150322376-A1 Fragrance Compositions THE PROCTER & GAMBLE COMPANY 2015-11-12 US disclosed
WO-2015171738-A2 FRAGRANCE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2015-11-12 WO disclosed
EP-2931854-A1 FRAGRANCE MATERIALS The Procter & Gamble Company (US) 2015-10-21 EP disclosed
EP-2931234-A2 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS The Procter and Gamble Company (US) 2015-10-21 EP disclosed
EP-2931236-A2 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS The Procter & Gamble Company (US) 2015-10-21 EP disclosed
CN-104902869-A Personal care compositions PROCTER & GAMBLE 2015-09-09 CN disclosed
CN-104837973-A Fragrance materials PROCTER & GAMBLE 2015-08-12 CN disclosed
EP-2775839-A2 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS The Regents of The University of California (US) 2014-09-17 EP disclosed
US-20140179722-A1 Antiperspirant and Deodorant Compositions THE PROCTER & GAMBLE COMPANY (US) 2014-06-26 US disclosed
WO-2014093807-A1 FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 WO disclosed
WO-2014093819-A2 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 WO disclosed
US-20140170101-A1 Antiperspirant and Deodorant Compositions THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 US disclosed
US-20140170194-A1 FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 US disclosed
WO-2014093747-A2 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 WO disclosed
WO-2013059364-A2 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-04-25 WO disclosed
US-6579553-B1 Reaction product cysteine, hydrogen sulfide, ammonium sulfide and extracellular liquid fusarium extracts used as food flavors ZENECA LIMITED (GB) 2003-06-17 US disclosed
CN-1285717-A Flavorants from yeast extracts MALRA FOOD CO (GB) 2001-02-28 CN disclosed
US-4980452-A Thermosettable prepolymers prepared from heterocyclic materials having alkyl substituents, mono- or dianhydrides, ethylenically unsaturated materials and a hydroxide, carbonate or bicarbonate of a metal of Groups I-A or II-A THE DOW CHEMICAL COMPANY (US) 1990-12-25 US disclosed
US-4927913-A Cured product from thermosettable prepolymer prepared from heterocyclic materials having alkyl substituents, mono- or dianhydrides, ethylenically unsaturated materials and a hydroxide, carbonate or bicarbonate of a metal of groups I-A or II-A THE DOW CHEMICAL COMPANY (US) 1990-05-22 US disclosed
US-4871848-A OIL, GAS WELLS CORROSION INHIBITORS THE DOW CHEMICAL COMPANY (US) 1989-10-03 US disclosed
US-4847355-A Thermosettable prepolymer prepared from heterocyclic material having alkyl substituents, mono- or dianhydride, ethylenically unsaturated material and a hydroxide, carbonate of bicarbonate of a metal of groups I-A or II-A THE DOW CHEMICAL COMPANY (US) 1989-07-11 US disclosed
US-4812531-A Thermosettable polymers or prepolymers prepared from heterocyclic materials having alkyl substituents, mono- or dianhydrides, ethylenically unsaturated materials and a hydroxide, carbonate or bicarbonate of a metal of groups I-A or II-A THE DOW CHEMICAL COMPANY (US) 1989-03-14 US disclosed
US-4752636-A Thermosettable polymer or prepolymer prepared from heterocyclic materials containing nitrogen atoms, carboxylic acid mono- or dianhydrides and a polymerizable material with ethylenically unsaturated groups and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1988-06-21 US disclosed
US-4740320-A REACTION OF NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPONENT, KETONE OR ALDEHYDE, AMINE OR POLYAMINE THE DOW CHEMICAL COMPANY (US) 1988-04-26 US disclosed
US-4725373-A CORROSION RESISTANCE FOR METAL TOOLS AND EQUIPMENT USED IN OIL AND GAS WELLS THE DOW CHEMICAL COMPANY (US) 1988-02-16 US disclosed
US-4724003-A Asphalt compositions containing anti-stripping additives prepared from hydrocarbyl substituted nitrogen-containing aromatic heterocyclic compounds, aldehydes or ketones and amines THE DOW CHEMICAL COMPANY (US) 1988-02-09 US disclosed
US-4676834-A Novel compositions prepared from methyl substituted nitrogen-containing aromatic heterocyclic compounds and an aldehyde or ketone THE DOW CHEMICAL COMPANY (US) 1987-06-30 US disclosed
US-4668766-A Preparation of thermosettable polymer or prepolymer from heterocyclic material containing nitrogen atoms, carboxylic acid mono- or dianhydride and a polymerizable material with ethylenically unsaturated group THE DOW CHEMICAL COMPANY (US) 1987-05-26 US disclosed
US-4654414-A Thermosettable polymer or prepolymer prepared from heterocyclic material having alkyl substituent, mono- or dianhydride, ethylenically unsaturated material and a hydroxide, carbonate or bicarbonate of a metal of groups I-A or II-A THE DOW CHEMICAL COMPANY (US) 1987-03-31 US disclosed
US-4613663-A Thermoplastic and thermosettable products prepared by reacting nitrogen-containing heterocyclic compounds with aromatic aldehydes THE DOW CHEMICAL COMPANY (US) 1986-09-23 US disclosed
US-4613663-A Thermoplastic and thermosettable products prepared by reacting nitrogen-containing heterocyclic compounds with aromatic aldehydes THE DOW CHEMICAL COMPANY (US) 1986-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533269-B2 Absorbent article comprising a fragrance and an odor control composition CUTA, CFD, MBTD1 HRH3 3318/4885PDE10A 363/4885NOS2 875/4885
US-20180064624-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS DRD4, DRD1, DRD5 HRH3 2592/4885PDE10A 156/4885NOS2 686/4885
US-20140170101-A1 Antiperspirant and Deodorant Compositions LPO, GPX4, DEK HRH3 484/4885PDE10A 824/4885NOS2 19/4885
US-20170312204-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS LPO, GPX4, DEK HRH3 484/4885PDE10A 824/4885NOS2 19/4885
US-11491099-B2 Antiperspirant and deodorant compositions DRD4, DRD1, DRD5 HRH3 2592/4885PDE10A 156/4885NOS2 686/4885
US-20260102294-A1 ABSORBENT ARTICLE COMPRISING A FRAGRANCE AND AN ODOR CONTROL COMPOSITION CUTA, SHBG, DSG1 HRH3 2920/4885PDE10A 185/4885NOS2 1083/4885
US-12533302-B2 Systems and methods for delivery of actives and healing tissue EXOSC10, PDGFA, EXOSC9 HRH3 2948/4885PDE10A 1450/4885NOS2 3428/4885
US-20180207074-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS LPO, GPX4, DEK HRH3 484/4885PDE10A 824/4885NOS2 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.