Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | ESR1 | P03372 | 6/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.76 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.76 |
| ▸ | DRD1 | P21728 | 1/20 | 0.76 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.76 |
| ▸ | KDR | P35968 | 1/20 | 0.76 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | ATM | Q13315 | 2/20 | 0.73 |
| ▸ | PGR | P06401 | 2/20 | 0.73 |
| ▸ | AR | P10275 | 2/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Estramustine SCHEMBL13753350 | 1.00 | RECQL (1.00) | RECQLBLMESR1ADORA3INPPL1 | |
| Estramustine SCHEMBL14031683 | 1.00 | RECQL (1.00) | RECQLBLMESR1ADORA3INPPL1 | |
| Estramustine SCHEMBL8173336 | 1.00 | RECQL (1.00) | RECQLBLMESR1ADORA3INPPL1 | |
| Estramustine SCHEMBL29374661 | 1.00 | RECQL (1.00) | RECQLBLMESR1ADORA3INPPL1 | |
| Estramustine SCHEMBL6353316 | 1.00 | RECQL (1.00) | RECQLBLMESR1ADORA3INPPL1 | |
| Estramustine SCHEMBL2348477 | 1.00 | RECQL (1.00) | RECQLBLMESR1ADORA3INPPL1 | |
| Estramustine SCHEMBL4252 | 1.00 | RECQL (1.00) | RECQLBLMESR1ADORA3INPPL1 | |
| Estramustine SCHEMBL29349776 | 1.00 | RECQL (1.00) | RECQLBLMESR1ADORA3INPPL1 | |
| Estramustine SCHEMBL679202 | 0.99 | RECQL (0.98) | RECQLBLMESR1ADORA3INPPL1 | |
| Estramustine SCHEMBL7621246 | 0.99 | RECQL (0.98) | RECQLBLMESR1ADORA3INPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637492-B2 | Peptide inhibitors of focal adhesion kinase activity and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-05-26 | — | — | US | disclosed |
| US-20260014080-A1 | LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF | VAN BOGAERT GINA (BE) | 2026-01-15 | — | — | US | disclosed |
| US-12521386-B2 | Small molecule inhibitors of the androgen receptor activity and/or expression and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-01-13 | — | — | US | disclosed |
| US-12509468-B2 | Quindoline compounds and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2025-12-30 | — | — | US | disclosed |
| US-11944626-B2 | Small molecule inhibitors of ALDH and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-04-02 | — | — | US | disclosed |
| WO-2023223235-A1 | LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF | PURNA PHARMACEUTICALS NV (BE) | 2023-11-23 | — | — | WO | disclosed |
| US-20230041761-A1 | SMALL MOLECULE MODULATORS OF SIGMA-1 AND SIGMA-2 RECEPTORS AND USES THEREOF | NORTHWESTERN UNIVERSITY | 2023-02-09 | — | — | US | disclosed |
| US-20220306692-A1 | PEPTIDE INHIBITORS OF FOCAL ADHESION KINASE ACTIVITY AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2022-09-29 | — | — | US | disclosed |
| US-20220098210-A1 | QUINDOLINE COMPOUNDS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-03-31 | — | — | US | disclosed |
| US-20220081412-A1 | QUINOLINYL-PYRAZINE-CARBOXAMIDE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2022-03-17 | — | — | US | disclosed |
| US-20220062278-A1 | SMALL MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR ACTIVITY AND/OR EXPRESSION AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-03-03 | — | — | US | disclosed |
| US-20030114379-A1 | Methods of treating or preventing cell, tissue, and organ damage using human myeloid progenitor inhibitory factor-1 (MPIF-1) | HUMAN GENOME SCIENCES, INC. | 2003-06-19 | — | — | US | disclosed |
| US-6495129-B1 | Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3) | HUMAN GENOME SCIENCES, INC. | 2002-12-17 | — | — | US | disclosed |
| WO-2001026676-A9 | METHODS OF TREATING OR PREVENTING CELL, TISSUE, AND ORGAN DAMAGE USING HUMAN MYELOID PROGENITOR INHIBITORY FACTOR-1 (MPIF-1) | HUMAN GENOME SCIENCES INC (US) | 2002-11-07 | — | — | WO | disclosed |
| US-6444420-B2 | NERVOUS SYSTEM DISORDERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2002-09-03 | — | — | US | disclosed |
| EP-1225911-A1 | METHODS OF TREATING OR PREVENTING CELL, TISSUE, AND ORGAN DAMAGE USING HUMAN MYELOID PROGENITOR INHIBITORY FACTOR-1 (MPIF-1) | Human Genome Sciences (US) | 2002-07-31 | — | — | EP | disclosed |
| US-20010016325-A1 | Activation of novel estrogen receptor supports and neuronal viability and function | BOARD OF TRUSTEE OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE | 2001-08-23 | — | — | US | disclosed |
| US-6265147-B1 | DETECTING MODULATORS OF BRAIN ACTIVITY; MIX MODULATOR WITH RECEPTORS AND DETECT ACTIVATION OF RECEPTORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2001-07-24 | — | — | US | disclosed |
| WO-2001039780-A1 | ACTIVATION OF NOVEL ESTROGEN RECEPTOR SUPPORTS NEURONAL VIABILITY AND FUNCTION | THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIVERSITY (US) | 2001-06-07 | — | — | WO | disclosed |
| WO-2001026676-A1 | METHODS OF TREATING OR PREVENTING CELL, TISSUE, AND ORGAN DAMAGE USING HUMAN MYELOID PROGENITOR INHIBITORY FACTOR-1 (MPIF-1) | HUMAN GENOME SCIENCES, INC. (US) | 2001-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081412-A1 | QUINOLINYL-PYRAZINE-CARBOXAMIDE COMPOUNDS AND USES THEREOF | HMGB3, HCCS, ACACA | RECQL 842/4885BLM 4262/4885ESR1 4121/4885 |
| US-20260014080-A1 | LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF | NR5A1, SHBG, GNRHR | RECQL 1381/4885BLM 3269/4885ESR1 188/4885 |
| US-20220098210-A1 | QUINDOLINE COMPOUNDS AND USES THEREOF | RECQL, XPO7, XPOT | RECQL 1/4885BLM 198/4885ESR1 819/4885 |
| US-12509468-B2 | Quindoline compounds and uses thereof | TPD52L2, BRDT, RECQL | RECQL 3/4885BLM 571/4885ESR1 481/4885 |
| US-20220062278-A1 | SMALL MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR ACTIVITY AND/OR EXPRESSION AND USES THEREOF | AR, KLK3, FSHR | RECQL 4803/4885BLM 4871/4885ESR1 41/4885 |
| US-11944626-B2 | Small molecule inhibitors of ALDH and uses thereof | ALDH2, ALDH1A1, ALDH3A1 | RECQL 505/4885BLM 4076/4885ESR1 2866/4885 |
| US-20220306692-A1 | PEPTIDE INHIBITORS OF FOCAL ADHESION KINASE ACTIVITY AND USES THEREOF | PTK2, LTK, LIMK2 | RECQL 3046/4885BLM 1231/4885ESR1 4623/4885 |
| US-20010016325-A1 | Activation of novel estrogen receptor supports and neuronal viability and function | ESR1, GPER1, ESR2 | RECQL 4455/4885BLM 4802/4885ESR1 1/4885 |
| US-12637492-B2 | Peptide inhibitors of focal adhesion kinase activity and uses thereof | PTK2, ILK, FPR2 | RECQL 3626/4885BLM 1631/4885ESR1 1821/4885 |
| US-20230041761-A1 | SMALL MOLECULE MODULATORS OF SIGMA-1 AND SIGMA-2 RECEPTORS AND USES THEREOF | SIGMAR1, TMEM97, OPRM1 | RECQL 2976/4885BLM 4799/4885ESR1 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.