Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482004 | 0.90 | ALDH1A1 (0.46) | MMP9MMP2MMP8MAPTBLM | |
| SCHEMBL7480698 | 0.87 | AKR1B1 (0.48) | MMP9MMP2MMP8MAPTBLM | |
| SCHEMBL7474643 | 0.86 | ALDH1A1 (0.45) | MMP9MMP2MAPTL3MBTL1POLB | |
| SCHEMBL7475641 | 0.86 | PTGS2 (0.44) | MMP9MMP2MMP8MAPTL3MBTL1 | |
| SCHEMBL7478795 | 0.86 | LMNA (0.45) | MMP9MMP2MMP8MAPTPOLB | |
| SCHEMBL7474409 | 0.84 | MAOA (0.54) | MAPTPOLBRECQLMEN1KMT2A | |
| SCHEMBL7470955 | 0.83 | HTT (0.46) | CYP3A4TSHRCYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL7482164 | 0.82 | MMP2 (0.49) | MMP9MMP2MMP8L3MBTL1ALDH1A1 | |
| SCHEMBL7478759 | 0.82 | MMP2 (0.43) | MMP9MMP2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7475491 | 0.82 | PLK1 (0.45) | MMP9MMP2MMP8POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869947-B1 | BARBITURIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 2002-10-23 | — | — | EP | disclosed |