SCHEMBL7559519

SCHEMBL7559519

CCCCCCCCCCCCCCCCCCOCC(CN)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.74
HTT P42858 1/20 0.61
LPAR1 Q92633 7/20 0.56
LPAR3 Q9UBY5 7/20 0.56
LPAR2 Q9HBW0 4/20 0.56
TLR2 O60603 8/20 0.55
USP2 O75604 1/20 0.48
PRKD3 O94806 1/20 0.46
PRKCG P05129 1/20 0.46
PRKCB P05771 1/20 0.46
PRKCA P17252 1/20 0.46
PRKCH P24723 1/20 0.46
PRKCI P41743 1/20 0.46
PRKCE Q02156 1/20 0.46
PRKCQ Q04759 1/20 0.46
PRKCZ Q05513 1/20 0.46
PRKCD Q05655 1/20 0.46
PRKD1 Q15139 1/20 0.46
LPAR6 P43657 3/20 0.45
LPAR4 Q99677 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564861 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2
SCHEMBL19839744 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2
SCHEMBL7558267 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2
SCHEMBL7560842 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2
SCHEMBL22589994 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2
SCHEMBL24470437 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2
SCHEMBL7560937 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2
SCHEMBL19839669 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2
SCHEMBL7564999 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2
SCHEMBL7557137 1.00 DNM1 (0.74) DNM1HTTLPAR1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002072068-A2 LIPIDS, LIPID COMPOSITIONS, LIPOSOMES, AND LIPOPLEXES CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2002-09-19 WO claimed
US-12545636-B2 Acyclic lipids and methods of use thereof RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2026-02-10 US disclosed
EP-4655402-A1 NUCLEIC ACID VACCINES FOR VARICELLA-ZOSTER VIRUS (VZV) Providence Therapeutics Holdings Inc. (CA) 2025-12-03 EP disclosed
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 US disclosed
US-20250313525-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MAN INC (US) 2025-10-09 US disclosed
US-20250154102-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MAN INC (US) 2025-05-15 US disclosed
EP-4522646-A2 APOE LIPOPROTEIN SYSTEMS Kisbee Therapeutics, Inc. (US) 2025-03-19 EP disclosed
US-20250073164-A1 IONIZABLE DISULFIDE LIPIDS AND LIPID NANOPARTICLES DERIVED THEREFROM PROVIDENCE THERAPEUTICS HOLDINGS INC. (CA) 2025-03-06 US disclosed
US-12215068-B2 Constrained lipids and methods of use thereof RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2025-02-04 US disclosed
EP-4452928-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF Renagade Therapeutics Management Inc. (US) 2024-10-30 EP disclosed
EP-3041938-A1 CIRCULAR POLYNUCLEOTIDES Moderna Therapeutics, Inc. (US) 2016-07-13 EP disclosed
US-20160194625-A1 CHIMERIC POLYNUCLEOTIDES MODERNATX, INC. 2016-07-07 US disclosed
US-20160194368-A1 CIRCULAR POLYNUCLEOTIDES MODERNA THERAPEUTICS, INC. (US) 2016-07-07 US disclosed
US-20160038612-A1 FORMULATION AND DELIVERY OF MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS ARES CAPITAL CORPORATION, AS AGENT 2016-02-11 US disclosed
WO-2016014846-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF INTRABODIES MODERNA THERAPEUTICS, INC. (US) 2016-01-28 WO disclosed
WO-2015105926-A1 POLYNUCLEOTIDES FOR THE IN VIVO PRODUCTION OF ANTIBODIES MODERNA THERAPEUTICS, INC. (US) 2015-07-16 WO disclosed
WO-2015038892-A1 POLYNUCLEOTIDE COMPOSITIONS CONTAINING AMINO ACIDS MODERNA THERAPEUTICS, INC. (US) 2015-03-19 WO disclosed
WO-2015034925-A1 CIRCULAR POLYNUCLEOTIDES MODERNA THERAPEUTICS, INC. (US) 2015-03-12 WO disclosed
WO-2015034928-A1 CHIMERIC POLYNUCLEOTIDES MODERNA THERAPEUTICS, INC. (US) 2015-03-12 WO disclosed
WO-2002072068-A2 LIPIDS, LIPID COMPOSITIONS, LIPOSOMES, AND LIPOPLEXES CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2002-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160038612-A1 FORMULATION AND DELIVERY OF MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS NSUN2, RNMT, ADAR DNM1 1822/4885HTT 457/4885LPAR1 1644/4885
US-20250313525-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP DNM1 1315/4885HTT 2652/4885LPAR1 262/4885
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR DNM1 4235/4885HTT 1246/4885LPAR1 114/4885
US-20250073164-A1 IONIZABLE DISULFIDE LIPIDS AND LIPID NANOPARTICLES DERIVED THEREFROM SGMS1, SGMS2, ABCB4 DNM1 3554/4885HTT 4142/4885LPAR1 616/4885
US-12545636-B2 Acyclic lipids and methods of use thereof PLTP, LNPEP, PCTP DNM1 625/4885HTT 2716/4885LPAR1 140/4885
US-20160194368-A1 CIRCULAR POLYNUCLEOTIDES POLN, POLRMT, POLI DNM1 1372/4885HTT 593/4885LPAR1 1429/4885
US-12215068-B2 Constrained lipids and methods of use thereof SGMS1, SGMS2, LNPEP DNM1 1315/4885HTT 2652/4885LPAR1 262/4885
US-20250154102-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP DNM1 1472/4885HTT 3454/4885LPAR1 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.