Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Syringic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.64 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.64 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.64 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.64 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.55 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.64 |
| ▸ | CA6 | P23280 | 2/20 | 0.64 |
| ▸ | CA7 | P43166 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL11023599 | 0.83 | TUBB4A (0.53) | CA1CA2LMNAKMT2AKDM4E | |
| SCHEMBL28521735 | 0.82 | CA1 (0.47) | PKMCA1CA2CA12CA4 | |
| SCHEMBL15288999 | 0.80 | PKM (0.72) | PKMCA1CA2CA12CA4 | |
| SCHEMBL27905025 | 0.80 | PKM (0.72) | PKMCA1CA2CA12CA4 | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL10838605 | 0.79 | TUBB4A (0.53) | LMNAKMT2AKDM4EALDH1A1CYP3A4 | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL9739811 | 0.79 | TUBB4A (0.53) | LMNAKMT2AKDM4EALDH1A1CYP3A4 | |
| Vanillic Acid SCHEMBL6697034 | 0.79 | MEN1 (0.70) | CA1CA2KMT2AGAAKDM4E | |
| Syringic Acid SCHEMBL27602358 | 0.78 | CA12 (1.00) | PKMCA1CA2CA12CA4 | |
| Acetosyringone SCHEMBL15511 | 0.78 | LMNA (1.00) | PKMCA1CA2CA12CA4 | |
| Syringic Acid SCHEMBL42751 | 0.78 | CA12 (1.00) | PKMCA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036278-B | Compositions and methods for treating cancers with atypical BRAF mutations | 生物医学谷探索股份有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-116036278-A | Compositions and methods for treating cancers with atypical BRAF mutations | 生物医学谷探索股份有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-110799245-B | Compositions and methods for treating cancer with atypical BRAF mutations | 生物医学谷探索股份有限公司 | 2022-08-09 | — | — | CN | claimed |
| EP-4628514-A1 | ANTIBACTERIAL RESIN AND MOLDED BODY COMPRISING SAME | LG CHEM, LTD. (KR) | 2025-10-08 | — | — | EP | disclosed |
| WO-2025005516-A1 | ANTIBACTERIAL RESIN AND MOLDED BODY COMPRISING SAME | 주식회사 엘지화학 | 2025-01-02 | — | — | WO | disclosed |
| CN-116036278-B | Compositions and methods for treating cancers with atypical BRAF mutations | 生物医学谷探索股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-116036278-A | Compositions and methods for treating cancers with atypical BRAF mutations | 生物医学谷探索股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110799245-B | Compositions and methods for treating cancer with atypical BRAF mutations | 生物医学谷探索股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| US-6340654-B1 | CAN EFFECTIVELY AND PERSISTENTLY DELAY AUTOGENEOUS DETERIORATIONS, SUCH AS DISCOLORATION AND SOFTENING, OF THE AGRICULTURAL/HORTICULTURAL PRODUCTS, STORAGE STABILITY | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1082906-A2 | Freshness-retaining agent and its use for agricultural or horticultural products | DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) | 2001-03-14 | — | — | EP | disclosed |