Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 3,4,5-Trimethoxybenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A known ✓ | P04350 | 3/20 | 0.53 |
| ▸ | TUBB known ✓ | P07437 | 3/20 | 0.53 |
| ▸ | TUBA3C known ✓ | P0DPH7 | 3/20 | 0.53 |
| ▸ | TUBA1B known ✓ | P68363 | 3/20 | 0.53 |
| ▸ | TUBA4A known ✓ | P68366 | 3/20 | 0.53 |
| ▸ | TUBB4B known ✓ | P68371 | 3/20 | 0.53 |
| ▸ | TUBB3 known ✓ | Q13509 | 3/20 | 0.53 |
| ▸ | TUBB2A known ✓ | Q13885 | 3/20 | 0.53 |
| ▸ | TUBB8 known ✓ | Q3ZCM7 | 3/20 | 0.53 |
| ▸ | TUBA3E known ✓ | Q6PEY2 | 3/20 | 0.53 |
| ▸ | TUBA1A known ✓ | Q71U36 | 3/20 | 0.53 |
| ▸ | TUBA1C known ✓ | Q9BQE3 | 3/20 | 0.53 |
| ▸ | TUBB6 known ✓ | Q9BUF5 | 3/20 | 0.53 |
| ▸ | TUBB2B known ✓ | Q9BVA1 | 3/20 | 0.53 |
| ▸ | TUBB1 known ✓ | Q9H4B7 | 3/20 | 0.53 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.48 |
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL10838605 | 0.96 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL9739811 | 0.96 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL10876051 | 0.86 | ALDH1A1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Syringic Acid SCHEMBL7700213 | 0.83 | PKM (0.64) | TPMTKMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL28521735 | 0.82 | CA1 (0.47) | TPMTKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL4819729 | 0.80 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4625442 | 0.80 | TUBB1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL6592 | 0.78 | TPMT (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4089388 | 0.78 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL27888195 | 0.78 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129016-A1 | PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2025-04-24 | — | — | US | disclosed |
| EP-0160760-A1 | Preparation of trimethoxybenzoate esters and trimethoxybenzoic acid | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1985-11-13 | — | — | EP | disclosed |
| US-4471134-A | Preparation of trimethoxybenzoate esters and trimethoxybenzoic acid | MALLINCKRODT, INC. (US) | 1984-09-11 | — | — | US | disclosed |
| US-4055653-A | Sulfur containing trialkoxybenzoylamino carboxylic acids | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-10-25 | — | — | US | disclosed |
| US-4010193-A | (ALKYLAMINO)ALKYL SUBSTITUTED BENZOATES, LOCAL ANESTHETIC, ANTIFIBRILLATORY, ANTIARRHYTHMIAL | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1977-03-01 | — | — | US | disclosed |
| US-3981910-A | Sulfur containing trialkoxybenzoylamino carboxylic acids | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129016-A1 | PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF | RCC2, PPOX, FTO | TUBB4A 3628/4885TUBB 4069/4885TUBA3C 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.