Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | NOS2 | P35228 | 3/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.41 |
| ▸ | NPY2R | P49146 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906163 | 0.89 | L3MBTL1 (0.36) | SLC7A5NPY2RALPIPKMPTGS1 | |
| SCHEMBL7709540 | 0.84 | NOS3 (0.43) | NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL7709457 | 0.83 | NOS3 (0.43) | NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL7706489 | 0.82 | NLRP3 (0.46) | NOS3NOS1NOS2SLC7A5 | |
| Phenylalanine SCHEMBL7906184 | 0.82 | SLC7A5 (0.52) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL7904116 | 0.77 | SLC7A5 (0.45) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7896693 | 0.77 | ITGB1 (0.47) | — | |
| SCHEMBL7905098 | 0.76 | ITGB1 (0.50) | — | |
| SCHEMBL6932583 | 0.76 | PTPN1 (0.46) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7908862 | 0.76 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362204-B1 | CONTROLLING IMMUNOLOGY; ANTIINFLAMMATORY AGENTS | CELLTECH THERAPEUTICS, LTD (GB) | 2002-03-26 | — | — | US | disclosed |