SCHEMBL7799766

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL344561	0.82	SMN1; SMN2 (0.62)	MAPTSMN1; SMN2ALDH1A1LMNAPKM
	SCHEMBL14966127	0.82	USP28 (0.62)	MAPK14ROCK1ROCK2USP28USP25
	SCHEMBL338641	0.80	MAPT (0.58)	MAPTSMN1; SMN2PLA2G1BATG4BALDH1A1
	SCHEMBL4598244	0.76	CHRM2 (0.54)	MAPK14ROCK1ROCK2USP28USP25
	SCHEMBL13647056	0.75	MAPK14 (0.63)	MAPK14ROCK1ROCK2GLSCNR1
	SCHEMBL5724446	0.75	MAPK14 (0.63)	MAPK14ROCK1ROCK2GLSCNR1
	SCHEMBL7802539	0.75	ALDH1A1 (0.56)	MAPTSMN1; SMN2PLA2G1BATG4BALDH1A1
	SCHEMBL344129	0.75	MAPT (0.57)	MAPTPLA2G1BATG4BALDH1A1LMNA
	SCHEMBL349644	0.75	ALDH1A1 (0.56)	MAPTSMN1; SMN2ALDH1A1LMNAPKM
	SCHEMBL7802300	0.75	ALOX12 (0.56)	MAPTALDH1A1LMNAPKMALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.