SCHEMBL800982

SCHEMBL800982

COc1cccc(OC)c1OCCNCC1COc2ccccc2O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 19/20 1.00
ADRA1A P35348 19/20 1.00
ADRA1B P35368 19/20 1.00
HTR1A P08908 5/20 1.00
ALDH1A1 P00352 2/20 1.00
MEN1 O00255 2/20 1.00
CYP3A4 P08684 2/20 1.00
KMT2A Q03164 2/20 1.00
KDM4E B2RXH2 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2D6 P10635 1/20 1.00
TSHR P16473 1/20 1.00
MAPK1 P28482 1/20 1.00
CYP2C19 P33261 1/20 1.00
THPO P40225 1/20 1.00
ADRA2A P08913 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
LMNA P02545 1/20 0.98
PMP22 Q01453 1/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387392 1.00 ADRA1D (1.00) ADRA1DADRA1AADRA1BHTR1AALDH1A1
Hydrochloric Acid SCHEMBL989002 0.99 ADRA1D (1.00) ADRA1DADRA1AADRA1BHTR1AALDH1A1
SCHEMBL9788808 0.90 ADRA1D (0.81) ADRA1DADRA1AADRA1BHTR1AALDH1A1
Hydrochloric Acid SCHEMBL15755824 0.89 ADRA1D (0.82) ADRA1DADRA1AADRA1BHTR1AALDH1A1
Ambenoxan SCHEMBL2109415 0.78 ADRA1D (0.64) ADRA1DADRA1AADRA1BHTR1AALDH1A1
SCHEMBL13533406 0.77 ADRA1D (0.63) ADRA1DADRA1AADRA1BHTR1AALDH1A1
SCHEMBL10751769 0.77 ADRA1D (0.63) ADRA1DADRA1AADRA1BHTR1AALDH1A1
SCHEMBL10750267 0.77 ADRA1D (0.63) ADRA1DADRA1AADRA1BHTR1AALDH1A1
SCHEMBL4279935 0.77 ADRA1D (0.62) ADRA1DADRA1AADRA1BHTR1AALDH1A1
SCHEMBL8097715 0.77 ADRA1B (0.85) ADRA1AADRA1BHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025034510-A1 ADRENERGIC ANTAGONISTS FOR USE IN A METHOD FOR TREATING CEREBRAL EDEMA OR A BRAIN INJURY UNIVERSITY OF ROCHESTER (US) 2025-02-13 WO claimed
US-20220093960-A1 BINDER SYSTEMS AND METHODS FOR TAPE CASTING LITHIUM GARNET ELECTROLYTES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-03-24 US claimed
US-20020035998-A1 Method for treatment of cancer and infectious disease HELLSTRAND KRISTOFFER (SE) 2002-03-28 US claimed
US-6305380-B1 ADMINISTERING HISTAMINE AGONIST OR HT3 RECEPTOR ANTAGONIST TO ACTIVATE NATURAL KILLER CELLS AND TREAT VIRAL DISEASES MAXIM PHARMACEUTICALS, INC. 2001-10-23 US claimed
WO-2001034124-A2 USE OF 5HT-1A-SEROTONINE RECEPTOR AGONISTS FOR TREATING GENETIC OR FUNCTIONAL RHYTHM DISORDERS IN THE RESPIRATORY SYSTEM RICHTER DIETHELM WOLFGANG (DE) 2001-05-17 WO claimed
US-6162455-A Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals AMERICAN CYANAMID COMPANY (US) 2000-12-19 US claimed
EP-0652768-B1 A pharmaceutical preparation for the synergistic activation of natural killer cells MAXIM PHARM INC (US) 2000-05-03 EP claimed
JP-9169607-A None JP disclosed
US-20260132334-A1 METHOD FOR PRODUCING A CERAMIC CONVERTER ELEMENT, CERAMIC CONVERTER ELEMENT, AND OPTOELECTRONIC COMPONENT OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2026-05-14 US disclosed
US-20260124785-A1 RAPID CERAMIC PROCESSING TECHNIQUES AND EQUIPMENT QUANTUMSCAPE BATTERY INC (US) 2026-05-07 US disclosed
US-20260109138-A1 PROCESSING APPARATUSES AND METHODS OF USING QUANTUMSCAPE BATTERY INC (US) 2026-04-23 US disclosed
EP-4711350-A2 RAPID THERMAL PROCESSING METHODS AND APPARATUS QuantumScape Battery, Inc. (US) 2026-03-18 EP disclosed
US-12533869-B2 Processing apparatuses and methods of using QUANTUMSCAPE BATTERY, INC. (US) 2026-01-27 US disclosed
US-4980365-A N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1990-12-25 US disclosed
US-4957914-A ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS SYNTEX (U.S.A.) INC. (US) 1990-09-18 US disclosed
EP-0299349-A2 N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1989-01-18 EP disclosed
EP-0025727-B1 INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM SANOFI S.A. (FR) 1984-03-28 EP disclosed
US-4411881-A Composition and method for stabilizing radiolabeled compounds using thiocarbonylated diethylenetriamines NEW ENGLAND NUCLEAR CORPORATION (US) 1983-10-25 US disclosed
US-4404217-A DRUGS ACTIVE ON CARDIOVASCULAR SYSTEM C. M. INDUSTRIES (FR) 1983-09-13 US disclosed
US-4305944-A TRANQUILIZERS, NEUROLEPTIC AGENTS MEAD JOHNSON & COMPANY (US) 1981-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533869-B2 Processing apparatuses and methods of using TMCO1, ZYX, CTSZ ADRA1D 4716/4885ADRA1A 4802/4885ADRA1B 4734/4885
US-20260132334-A1 METHOD FOR PRODUCING A CERAMIC CONVERTER ELEMENT, CERAMIC CONVERTER ELEMENT, AND OPTOELECTRONIC COMPONENT WNT3, SPOP, YAP1 ADRA1D 4849/4885ADRA1A 4813/4885ADRA1B 4853/4885
US-20260124785-A1 RAPID CERAMIC PROCESSING TECHNIQUES AND EQUIPMENT ABL1, BCR, SETDB1 ADRA1D 4051/4885ADRA1A 4623/4885ADRA1B 4325/4885
US-20260109138-A1 PROCESSING APPARATUSES AND METHODS OF USING DSP, TMEM63A, DSG1 ADRA1D 4676/4885ADRA1A 4800/4885ADRA1B 4781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.