SCHEMBL803151

SCHEMBL803151

Cc1nn(C)c(OCC(F)(F)F)c1C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
SCN9A Q15858 3/20 0.34
NR3C1 P04150 1/20 0.34
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5369514 0.84 LMNA (0.36) POLBSCN9APTGS1PTGS2PKM
SCHEMBL3158933 0.80 SMN1; SMN2 (0.36) POLBNR3C1PKM
SCHEMBL3154381 0.78 SMN1; SMN2 (0.47) POLBNR3C1PKM
SCHEMBL24553662 0.76 MPO (0.34) NR3C1PKM
SCHEMBL12856407 0.76 POLB (0.33) POLB
SCHEMBL14461311 0.74 ABCB1 (0.33) SCN9A
SCHEMBL4554933 0.71 LMNA (0.35) POLBSCN9A
SCHEMBL19058804 0.71 POLB (0.37) POLBSCN9A
SCHEMBL26945694 0.70 SCN9A (0.36) SCN9APTGS1PTGS2PKM
SCHEMBL4866525 0.70 LMNA (0.36) POLBSCN9APTGS1PTGS2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026371-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF AGRO BV (NL) 2024-01-25 US disclosed
US-10041087-B2 Plants having increased tolerance to herbicides BASF Agro B.V. (NL) 2018-08-07 US disclosed
US-9926284-B2 Substituted N-(1,2,4-triazol-3-yl)Arylcarboxamide compounds and their use as herbicides BASF SE (DE) 2018-03-27 US disclosed
US-9902704-B2 Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamide compounds and their use as herbicides BASF SE (DE) 2018-02-27 US disclosed
US-20170339955-A1 Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamide compounds and their use as herbicides BASF SE (DE) 2017-11-30 US disclosed
US-9497961-B2 Composition for improving the efficacy of herbicides BASF SE (DE) 2016-11-22 US disclosed
US-20160295866-A1 COMPOSITION OF 1,5-DIMETHYL-6-THIOXO-3-(2,2,7-TRIFLUORO-3-OXO-4-(PROP-2-YNYL)-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-YL)-1,3,5-TRIAZINANE-2,4-DIONE BASF SE (DE) 2016-10-13 US disclosed
US-20160251322-A1 Substituted N-(Tetrazol-5-yl)- and N-(Triazol-5-yl)arylcarboxamide Compounds and Their Use as Herbicides BASF SE (DE) 2016-09-01 US disclosed
US-9398768-B2 Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)pyridin-3-yl-carboxamide compounds and their use as herbicides BASF SE (DE) 2016-07-26 US disclosed
US-20160200692-A1 Substituted N-(1,2,4-Triazol-3-yl)Arylcarboxamide Compounds and Their Use as Herbicides BASF SE (DE) 2016-07-14 US disclosed
US-20120077678-A1 Substituted Pyrazine (Thio)Pyrans with a Herbicidal Action BASF SE (DE) 2012-03-29 US disclosed
US-20120071322-A1 Substituted Pyridopyrazines with a Herbicidal Action BASF SE (DE) 2012-03-22 US disclosed
US-20110251063-A1 HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION BASF SE (DE) 2011-10-13 US disclosed
US-20110224078-A1 Substituted Pyridines Having a Herbicidal Effect BASF SE (DE) 2011-09-15 US disclosed
US-20110207609-A1 Piperazine Compounds With Herbicidal Effect BASF SE (DE) 2011-08-25 US disclosed
US-20110201501-A1 Substituted Pyridines Having a Herbicidal Effect BASF SE (DE) 2011-08-18 US disclosed
US-20110183848-A1 Piperazine Compounds With Herbicidal Effect BASF SE (DE) 2011-07-28 US disclosed
US-20110177949-A1 Composition for Improving the Efficacy of Herbicides BASF SE (DE) 2011-07-21 US disclosed
US-20110130286-A1 Piperazine Compounds with Herbicidal Effect BASF SE (DE) 2011-06-02 US disclosed
US-20110105329-A1 Substituted Quinolinones Having Herbicidal Action BASF SE (DE) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200692-A1 Substituted N-(1,2,4-Triazol-3-yl)Arylcarboxamide Compounds and Their Use as Herbicides CBR3, NR2C2, CNPY2 POLB 4631/4885SCN9A 1483/4885NR3C1 1087/4885
US-10041087-B2 Plants having increased tolerance to herbicides PPOX, PNPO, PAOX POLB 493/4885SCN9A 3669/4885NR3C1 3512/4885
US-20110201501-A1 Substituted Pyridines Having a Herbicidal Effect DDT, PNPO, HPD POLB 2069/4885SCN9A 2946/4885NR3C1 2956/4885
US-20110183848-A1 Piperazine Compounds With Herbicidal Effect CAT, DDT, CIP2A POLB 1261/4885SCN9A 3954/4885NR3C1 4205/4885
US-20110207609-A1 Piperazine Compounds With Herbicidal Effect CAT, DDT, CIP2A POLB 1283/4885SCN9A 3947/4885NR3C1 4191/4885
US-20240026371-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES PPOX, PNPO, PAOX POLB 493/4885SCN9A 3669/4885NR3C1 3512/4885
US-20110177949-A1 Composition for Improving the Efficacy of Herbicides DDT, AS3MT, PAOX POLB 1873/4885SCN9A 4111/4885NR3C1 4211/4885
US-20120077678-A1 Substituted Pyrazine (Thio)Pyrans with a Herbicidal Action PFAS, TST, TPMT POLB 1990/4885SCN9A 2763/4885NR3C1 2469/4885
US-20160251322-A1 Substituted N-(Tetrazol-5-yl)- and N-(Triazol-5-yl)arylcarboxamide Compounds and Their Use as Herbicides NAT1, NT5C, AADAC POLB 4126/4885SCN9A 1020/4885NR3C1 804/4885
US-20170339955-A1 Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamide compounds and their use as herbicides NAT1, AADAC, DDT POLB 4422/4885SCN9A 1254/4885NR3C1 1049/4885
US-20120071322-A1 Substituted Pyridopyrazines with a Herbicidal Action PLPBP, PNPO, PFAS POLB 1341/4885SCN9A 3710/4885NR3C1 2929/4885
US-20110251063-A1 HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION DDT, KHK, HK1 POLB 1945/4885SCN9A 3142/4885NR3C1 3345/4885
US-20110224078-A1 Substituted Pyridines Having a Herbicidal Effect DDT, PNPO, HPD POLB 2069/4885SCN9A 2946/4885NR3C1 2956/4885
US-20110105329-A1 Substituted Quinolinones Having Herbicidal Action DDT, NQO2, CYP1A1 POLB 1141/4885SCN9A 1746/4885NR3C1 3710/4885
US-20160295866-A1 COMPOSITION OF 1,5-DIMETHYL-6-THIOXO-3-(2,2,7-TRIFLUORO-3-OXO-4-(PROP-2-YNYL)-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-YL)-1,3,5-TRIAZINANE-2,4-DIONE TXN2, COX5A, PRDX5 POLB 1349/4885SCN9A 2736/4885NR3C1 1672/4885
US-20110130286-A1 Piperazine Compounds with Herbicidal Effect CAT, DDT, CIP2A POLB 1261/4885SCN9A 3954/4885NR3C1 4205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.