Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12188736 | 0.84 | NAPRT (0.50) | NAPRTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10031827 | 0.82 | PGR (0.47) | ALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL5649378 | 0.77 | LMNA (0.44) | NAPRTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4667987 | 0.77 | LMNA (0.44) | NAPRTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5197379 | 0.77 | KDM4E (0.52) | NAPRTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5649382 | 0.77 | LMNA (0.44) | NAPRTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28593689 | 0.77 | NAPRT (0.43) | NAPRTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL17773170 | 0.77 | MKNK1 (0.47) | CYP1A2CYP3A4 | |
| SCHEMBL26907129 | 0.76 | CES1 (0.60) | NAPRTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25006960 | 0.76 | HCAR2 (0.57) | NAPRTALDH1A1LMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230398223-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-12-14 | — | — | US | disclosed |
| US-20230398223-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-12-14 | — | — | US | disclosed |
| US-11723980-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-20230030115-A1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO LTD (CN) | 2023-02-02 | — | — | US | disclosed |
| US-11161846-B2 | Substituted pyrazolo[4,3-b]pyridines and their use as GluN2B receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2021-11-02 | — | — | US | disclosed |
| US-11130749-B2 | — | — | 2021-09-28 | — | — | US | disclosed |
| US-11066392-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-20 | — | — | US | disclosed |
| US-11020334-B2 | Compounds, compositions and use thereof | ILLUSTRIS PHARMACEUTICALS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-10927088-B2 | Thymoquinone derivatives for treatment of cancer | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2021-02-23 | — | — | US | disclosed |
| US-20200392130-A1 | SUBSTITUTED PYRAZOLO[4,3-b]PYRIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | US | disclosed |
| US-20070154927-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154926-A1 | Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154924-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154925-A1 | METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| WO-2007060408-A2 | L-PHENYLALANINE DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | ASTRAZENECA AB (SE) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007060409-A1 | L-ALANINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-05-31 | — | — | WO | disclosed |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
| US-20070054933-A1 | 17-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC (US) | 2007-03-08 | — | — | US | disclosed |
| US-4128651-A | Bis-quaternary pyridinium-2-aldoxime salts and a process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-12-05 | — | — | US | disclosed |
| US-4098908-A | PHENOXYPHENYL PYRIDYL KETONES AND DERIVATIVES AND THEIR USE AS HYPOLEPIDEMIC AGENTS | SANDOZ, INC. (US) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070154924-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RPS28 | NAPRT 2539/4885ALDH1A1 587/4885MEN1 3292/4885 |
| US-20200392130-A1 | SUBSTITUTED PYRAZOLO[4,3-b]PYRIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | GRIN2B, GRIN3B, GRIN3A | NAPRT 617/4885ALDH1A1 2061/4885MEN1 4821/4885 |
| US-11020334-B2 | Compounds, compositions and use thereof | RARB, RARA, RARG | NAPRT 45/4885ALDH1A1 46/4885MEN1 3516/4885 |
| US-11723980-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | NAPRT 1634/4885ALDH1A1 2776/4885MEN1 4055/4885 |
| US-10927088-B2 | Thymoquinone derivatives for treatment of cancer | TYMS, TYMP, NQO1 | NAPRT 360/4885ALDH1A1 324/4885MEN1 1210/4885 |
| US-20070154926-A1 | Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence | SLC25A21, RPS28, ZCCHC8 | NAPRT 2728/4885ALDH1A1 476/4885MEN1 3434/4885 |
| US-20230030115-A1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | ROCK1, ROCK2, RHOA | NAPRT 3355/4885ALDH1A1 4501/4885MEN1 1685/4885 |
| US-11130749-B2 | — | ROCK1, RHOA, ROCK2 | NAPRT 4124/4885ALDH1A1 4171/4885MEN1 1552/4885 |
| US-11161846-B2 | Substituted pyrazolo[4,3-b]pyridines and their use as GluN2B receptor modulators | GRIN2B, GRIN3B, GRIN3A | NAPRT 617/4885ALDH1A1 2061/4885MEN1 4821/4885 |
| US-11066392-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | IDO1, IDO2, INMT | NAPRT 531/4885ALDH1A1 797/4885MEN1 2594/4885 |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | NAPRT 3767/4885ALDH1A1 1079/4885MEN1 3032/4885 |
| US-20230398223-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | NAPRT 1634/4885ALDH1A1 2776/4885MEN1 4055/4885 |
| US-20070054933-A1 | 17-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators | AR, SHBG, NR5A1 | NAPRT 4272/4885ALDH1A1 1800/4885MEN1 2893/4885 |
| US-20070154925-A1 | METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES | POLRMT, NOP2, NSUN3 | NAPRT 1219/4885ALDH1A1 1468/4885MEN1 4042/4885 |
| US-20070154927-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | SLC25A21, ZCCHC8, SLC25A1 | NAPRT 3184/4885ALDH1A1 290/4885MEN1 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.