Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027754 | 0.89 | ALDH1A1 (0.41) | KDM4ERAB9ATDP1KMT2AGLA | |
| SCHEMBL8037899 | 0.88 | MAPT (0.51) | TSPORAB9AMAPTTDP1KMT2A | |
| SCHEMBL8037870 | 0.87 | LTA4H (0.46) | TSPORAB9AMAPTTDP1KMT2A | |
| SCHEMBL8037882 | 0.85 | LTA4H (0.48) | TSPOMAPTSMN1; SMN2LTA4HL3MBTL1 | |
| SCHEMBL8044175 | 0.82 | TSPO (0.43) | TSPOKDM4EMAPTTDP1KMT2A | |
| SCHEMBL6405714 | 0.82 | ALOX5 (0.47) | TSPORAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6403207 | 0.81 | TSPO (0.45) | TSPOTDP1KMT2ASMN1; SMN2LTA4H | |
| SCHEMBL8039724 | 0.80 | TSPO (0.41) | TSPOKDM4ERAB9AMAPTTDP1 | |
| SCHEMBL8039723 | 0.78 | PNLIP (0.47) | TSPOKDM4EMAPTTDP1KMT2A | |
| SCHEMBL8038284 | 0.78 | ALDH1A1 (0.49) | TSPORAB9AMAPTSMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |