Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224570 | 0.77 | L3MBTL1 (0.43) | ALDH1A1LMNASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL957751 | 0.74 | LMNA (0.48) | ALDH1A1POLBLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL15958975 | 0.69 | FABP4 (0.51) | ALDH1A1LMNASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL23432271 | 0.68 | ADRA2A (0.33) | — | |
| SCHEMBL5864048 | 0.67 | DHPS (0.58) | ALDH1A1POLBLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL28801601 | 0.66 | ALDH1A1 (0.61) | ALDH1A1POLBLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL1761246 | 0.66 | ALDH1A1 (0.41) | ALDH1A1POLBLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL31749760 | 0.65 | IDH1 (0.52) | ALDH1A1POLBLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL32689537 | 0.64 | LTA4H (0.47) | ALDH1A1POLBLMNAHTTKDM4E | |
| SCHEMBL5780419 | 0.64 | ALOX5 (0.55) | ALDH1A1POLBRAB9AALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073777-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |