SCHEMBL815505

SCHEMBL815505

C=C1N(C)C(=O)N(C)C(=O)N1C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
MGLL Q99685 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10070690 0.97
SCHEMBL23625443 0.93 ADRA2C (0.33) ADRA2CGSK3AGSK3BMGLLMEN1
SCHEMBL2601688 0.82
SCHEMBL23664431 0.81 GSK3A (0.33) GSK3AGSK3B
SCHEMBL16705492 0.71 CRBN (0.32) GSK3AGSK3BMGLLKMT2A
SCHEMBL12220326 0.71 ADRA2C (0.32) ADRA2CGSK3AGSK3BMGLLMEN1
SCHEMBL10095225 0.69 ADRA2C (0.30) ADRA2CGSK3AGSK3BMGLLMEN1
SCHEMBL19975673 0.69 LMNA (0.33) GSK3AGSK3BMGLL
SCHEMBL26415120 0.69 CRBN (0.31) ADRA2CGSK3AGSK3BMGLLMEN1
SCHEMBL9612275 0.69 GSK3A (0.32) GSK3AGSK3BMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132686-A1 STORAGE-STABLE POLYISOCYANATE COMPOSITION AND PREPARATION METHOD WANHUA CHEMICAL GROUP CO., LTD. (CN) 2023-05-04 US disclosed
EP-3383924-B1 REDOX POLYMERIZABLE COMPOSITION WITH PHOTOLABILE REDUCING AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2021-04-14 EP disclosed
EP-2976323-B1 HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2020-07-15 EP disclosed
US-20180217498-A1 PHOTOACTIVABLE NITROGEN BASES BASF SE (DE) 2018-08-02 US disclosed
US-10022306-B2 Dental compositions comprising a fatty mono(meth)acrylate 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-07-17 US disclosed
US-9988481-B2 Polyisocyanate composition, coating composition, coating film and method for producing same, and humidity stabilization method ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-06-05 US disclosed
US-9951200-B2 Thermoplastic compositions suitable for use in films SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-04-24 US disclosed
US-9921477-B2 Photoactivable nitrogen bases BASE SE (DE) 2018-03-20 US disclosed
US-9907733-B2 Dental compositions comprising addition-fragmentation agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-03-06 US disclosed
US-20180044448-A1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES COMPANY 2018-02-15 US disclosed
US-20100068650-A1 POSITIVE-WORKING RADIATION-SENSITIVE COMPOSITION AND METHOD FOR RESIST PATTERN FORMATION USING THE COMPOSITION JSR CORPORATION (JP) 2010-03-18 US disclosed
US-20090258041-A1 Protection of Oxidizable Agents CIBA CORP. 2009-10-15 US disclosed
WO-2009065743-A1 RADIATION CURABLE COMPOSITIONS CYTEC SURFACE SPECIALTIES, S.A. (BE) 2009-05-28 WO disclosed
US-20090092561-A1 Body-care and household products and compositions comprising specific sulfur-containing compounds BASF SE (DE) 2009-04-09 US disclosed
US-20080305055-A1 Anti-Radical Agents CIBA CORPORATION 2008-12-11 US disclosed
US-7410940-B2 Antioxidants for the stabilization of surfactant formulations CIBA SPECIALTY CHEMICALS CORP. (US) 2008-08-12 US disclosed
EP-1073686-B1 METHOD FOR PREPARING LOW VISCOSITY TRICONDENSATE POLYFUNCTIONAL ISOCYANATES RHODIA CHIMIE SA (FR) 2008-05-14 EP disclosed
US-20080108540-A1 Antioxidants for the stabilization of formulations comprising surfactants HUEGLIN DIETMAR 2008-05-08 US disclosed
US-20080003438-A1 Heterocyclic siloxanes for use in biocidal coatings and materials AUBURN UNIVERSITY (US) 2008-01-03 US disclosed
US-7288213-B1 Method for preparing low viscosity tricondensate polyfunctional isocyanates RHODIA CHIMIE (FR) 2007-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044448-A1 ADDITION-FRAGMENTATION OLIGOMERS ECPAS, ITGA8, NBAS ADRA2C 3676/4885GSK3A 4396/4885GSK3B 4451/4885
US-20080305055-A1 Anti-Radical Agents NOS3, GSTO1, PTGS1 ADRA2C 810/4885GSK3A 2084/4885GSK3B 2175/4885
US-20090258041-A1 Protection of Oxidizable Agents LPO, TYR, HAO2 ADRA2C 1948/4885GSK3A 4359/4885GSK3B 4531/4885
US-20090092561-A1 Body-care and household products and compositions comprising specific sulfur-containing compounds DSC1, SCLY, DSG1 ADRA2C 4801/4885GSK3A 4754/4885GSK3B 4664/4885
US-10022306-B2 Dental compositions comprising a fatty mono(meth)acrylate MMAB, ELOVL5, ELOVL1 ADRA2C 4299/4885GSK3A 4218/4885GSK3B 4600/4885
US-20180217498-A1 PHOTOACTIVABLE NITROGEN BASES CBR1, NR0B1, NR0B2 ADRA2C 587/4885GSK3A 3665/4885GSK3B 3528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.