Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851750 | 0.76 | PNMT (0.42) | ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL30585506 | 0.76 | PNMT (0.42) | ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL814890 | 0.73 | TP53 (0.33) | ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL217952 | 0.72 | TP53 (0.35) | ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL1029121 | 0.72 | DNMT1 (0.35) | — | |
| SCHEMBL5557769 | 0.70 | MAOA (0.31) | — | |
| SCHEMBL7511602 | 0.69 | PNMT (0.39) | ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL8304317 | 0.68 | NQO1 (0.31) | ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL22972 | 0.68 | ALDH1A1 (0.43) | ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL7524851 | 0.67 | ACHE (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539993-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| EP-3022233-B1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-03-08 | — | — | US | disclosed |
| US-9834628-B2 | Cyclopropyl substituted metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-12-05 | — | — | US | disclosed |
| EP-1960411-B1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| EP-3022233-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| WO-2015009473-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| US-20150025207-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-7538168-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-05-26 | — | — | US | disclosed |
| US-7446216-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135593-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-08-17 | — | — | US | disclosed |
| US-20060160967-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-07-20 | — | — | US | disclosed |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | OPRM1, POLM, AP1M1 | ALDH1A1 3259/4885HIF1A 3911/4885CYP1B1 855/4885 |
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | B2M, CDYL, MLX | ALDH1A1 2587/4885HIF1A 1655/4885CYP1B1 624/4885 |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | SP1, TTL, TTLL12 | ALDH1A1 2182/4885HIF1A 1209/4885CYP1B1 664/4885 |
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | MLX, AP1M1, AP2M1 | ALDH1A1 1617/4885HIF1A 3290/4885CYP1B1 990/4885 |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | AP2M1, AP1M1, CPNE4 | ALDH1A1 1770/4885HIF1A 777/4885CYP1B1 1359/4885 |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | CPNE4, TIMM13, NECTIN4 | ALDH1A1 767/4885HIF1A 2446/4885CYP1B1 409/4885 |
| US-20070135593-A1 | Halogen substituted metallocene compounds for olefin polymerization | ZKSCAN2, ZRANB2, ZC3H18 | ALDH1A1 1684/4885HIF1A 4380/4885CYP1B1 552/4885 |
| US-20060160967-A1 | Halogen substituted metallocene compounds for olefin polymerization | OR10J3, ZRANB2, SLC39A3 | ALDH1A1 2730/4885HIF1A 4496/4885CYP1B1 862/4885 |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | OSBP, OSBPL3, OSBP2 | ALDH1A1 2387/4885HIF1A 2989/4885CYP1B1 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.