SCHEMBL822930

SCHEMBL822930

Cc1ccc(C(=O)CCC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 1.00
NR4A2 P43354 1/20 0.65
USP5 P45974 1/20 0.63
RAB9A P51151 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
FFAR1 O14842 1/20 0.62
LMNA P02545 1/20 0.62
CYP1A2 P05177 1/20 0.62
HIF1A Q16665 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.61
MEN1 O00255 3/20 0.59
ALDH1A1 P00352 2/20 0.59
NPC1 O15118 1/20 0.59
GAA P10253 1/20 0.59
CYP2C19 P33261 1/20 0.59
GSK3B P49841 1/20 0.57
CTNNB1 P35222 3/20 0.56
WNT3A P56704 3/20 0.56
MMP2 P08253 1/20 0.53
MMP12 P39900 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL8467793 1.00 KMT2A (1.00) KMT2ANR4A2USP5RAB9ASMN1; SMN2
SCHEMBL16922187 1.00 KMT2A (1.00) KMT2ANR4A2USP5RAB9ASMN1; SMN2
SCHEMBL7857467 0.94 KMT2A (0.89) KMT2ANR4A2USP5RAB9ASMN1; SMN2
SCHEMBL16552778 0.91 KMT2A (0.83) KMT2ARAB9ASMN1; SMN2LMNAL3MBTL1
SCHEMBL8467798 0.89 KMT2A (0.79) KMT2ANR4A2USP5RAB9ASMN1; SMN2
SCHEMBL10353454 0.89 NR4A2 (0.81) KMT2ANR4A2USP5RAB9ASMN1; SMN2
SCHEMBL5849125 0.88 KMT2A (0.78) KMT2ANR4A2USP5RAB9ASMN1; SMN2
SCHEMBL2743310 0.88 KMT2A (0.78) KMT2ANR4A2USP5RAB9ASMN1; SMN2
SCHEMBL8269520 0.87 KMT2A (0.77) KMT2ANR4A2RAB9ASMN1; SMN2FFAR1
SCHEMBL6930410 0.86 KMT2A (0.74) KMT2ANR4A2USP5RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584034-B2 Coating composition for forming a flexible dielectric coat with high dielectric permittivity TRIBI Technologies d.o.o. (HR) 2026-03-24 US claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
US-20250154372-A1 COATING COMPOSITION FOR FORMING A FLEXIBLE DIELECTRIC COAT WITH HIGH DIELECTRIC PERMITTIVITY YELLOW DOT D.O.O. (HR) 2025-05-15 US claimed
CN-108752273-A A kind of preparation method of Cinchonic Acid's derivative of 3- straight chained alkyls carboxyl substitution 湖北欣瑞康医药科技有限公司 2018-11-06 CN claimed
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS PLATINUM MONTAUR LIFE SCIENCES, LLC AND AS AGENT (KY) 2017-07-06 US claimed
EP-3110427-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE Urigen Pharmaceuticals, Inc. (US) 2017-01-04 EP claimed
EP-1745004-B1 ARYL KETONE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS EMISPHERE TECH INC (US) 2016-05-18 EP claimed
WO-2015127416-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE URIGEN PHARMACEUTICALS, INC. (US) 2015-08-27 WO claimed
US-9035085-B2 Aryl ketone compounds and compositions for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2015-05-19 US claimed
US-7691889-B2 Antimycobacterial compounds LUPIN LIMITED (IN) 2010-04-06 US claimed
US-7422649-B2 Method for recording information in luminescent compositions and uses thereof in articles of manufacture AMERICAN DYE SOURCE, INC. (CA) 2008-09-09 US claimed
US-20080167217-A1 aryl ketone compounds and compositions containing them which facilitate the delivery of active agents. The aryl ketone compounds have the formula** Image-1or a salt thereof, where n=1 to 9, and R1 to R5 are independently hydrogen, C1 to C4 alkyl, C1 to C4 alkoxy, C2 to C4 alkenyl, halogen, hydroxyl, EMISPHERE TECHNOLOGIES, INC. (US) 2008-07-10 US claimed
US-20050192275-A1 Novel antimycobacterial compounds LUPIN LIMITED (IN) 2005-09-01 US claimed
US-6921839-B2 Synthesis of N,N-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem RANBAXY LABORATORIES LIMITED (IN) 2005-07-26 US claimed
US-20040054230-A1 Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem RANBAXY LABORATORIES LIMITED (IN) 2004-03-18 US claimed
EP-1370515-A2 SYNTHESIS OF N,N-DIMETHYL-3-(4-METHYL) BENZOYL PROPIONAMIDE, A KEY INTERMEDIATE OF ZOLPIDEM RANBAXY LABORATORIES, LTD. (IN) 2003-12-17 EP claimed
WO-2002018303-A2 SYNTHESIS OF N,N-DIMETHYL-3-(4-METHYL) BENZOYL PROPIONAMIDE, A KEY INTERMEDIATE OF ZOLPIDEM RANBAXY LABORATORIES LIMITED (IN) 2002-03-07 WO claimed
JP-6321851-A None JP disclosed
US-4058529-A Polycyclic amino derivatives of pyrrolidone and piperidone CIBA-GEIGY CORPORATION (US) 1977-11-15 US disclosed
US-4052395-A AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES SANKYO COMPANY LIMITED (JA) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584034-B2 Coating composition for forming a flexible dielectric coat with high dielectric permittivity CACNA2D3, PLOD3, CACNA2D1 KMT2A 4027/4885NR4A2 2190/4885USP5 2494/4885
US-20040054230-A1 Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem GABRA4, GABRA3, GABRA6 KMT2A 80/4885NR4A2 416/4885USP5 1540/4885
US-20050192275-A1 Novel antimycobacterial compounds MDH1, IMMT, MLYCD KMT2A 3434/4885NR4A2 4005/4885USP5 3327/4885
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS SI, SLC20A1, SLC20A2 KMT2A 4752/4885NR4A2 3782/4885USP5 1434/4885
US-20080167217-A1 aryl ketone compounds and compositions containing them which facilitate the delivery of active agents. The aryl ketone compounds have the formula** Image-1or a salt thereof, where n=1 to 9, and R1 to R5 are independently hydrogen, C1 to C4 alkyl, C1 to C4 alkoxy, C2 to C4 alkenyl, halogen, hydroxyl, AKR1C3, AKR1C1, AKR1A1 KMT2A 1376/4885NR4A2 738/4885USP5 2241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.