SCHEMBL8326170

SCHEMBL8326170

Fc1ccc2nonc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.54
EPAS1 Q99814 2/20 0.47
KDM4E B2RXH2 1/20 0.43
KMT2A Q03164 2/20 0.42
KCNJ1 P48048 1/20 0.40
KCNH2 Q12809 1/20 0.40
BACE1 P56817 1/20 0.39
POLB P06746 2/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
GRIA3 P42263 1/20 0.37
GRIA4 P48058 1/20 0.37
RPS6KA5 O75582 2/20 0.36
AXL P30530 1/20 0.36
GFER P55789 1/20 0.36
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22092691 0.75 NPC1 (0.68) EPAS1KMT2APOLBNPC1MAPT
SCHEMBL3078778 0.74 ENPP2 (0.58) ENPP2EPAS1KDM4EKCNJ1KCNH2
SCHEMBL14666982 0.73 ENPP2 (0.44) ENPP2EPAS1KMT2AKCNJ1KCNH2
SCHEMBL13610351 0.71 ALDH1A1 (0.48) ENPP2EPAS1KDM4EKMT2AKCNJ1
SCHEMBL298552 0.70 ENPP2 (0.54) ENPP2EPAS1KMT2AKCNJ1KCNH2
SCHEMBL13928717 0.70 ENPP2 (0.54) ENPP2EPAS1KDM4EKCNJ1KCNH2
SCHEMBL3038439 0.70 ENPP2 (0.54) ENPP2EPAS1KCNJ1KCNH2POLB
SCHEMBL1358998 0.70 ENPP2 (1.00) ENPP2KDM4EKMT2AKCNJ1KCNH2
SCHEMBL3191645 0.70 ENPP2 (0.54) ENPP2KDM4EKMT2AKCNJ1KCNH2
SCHEMBL2708419 0.70 ENPP2 (0.54) ENPP2EPAS1KDM4EKMT2AKCNJ1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071782-A Use of donor-acceptor polymers based on fluorobenzooxadiazoles in electronics and photonics 香港科技大学 2018-12-21 CN claimed
US-20180355099-A1 Fluorinated Benzoxadiazole-Based Donor-Acceptor Polymers for Electronic and Photonic Applications THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2018-12-13 US claimed
US-20250327100-A1 Strain of Pseudomonas Putida Genetically Modified to Express a Benzalacetone Reductase BGENE GENETICS (FR) 2025-10-23 US disclosed
US-20240368173-A1 TRICYCLIC GPR65 MODULATORS Pathios Therapeutics Limited (GB) 2024-11-07 US disclosed
US-12075697-B2 Inert solution-processable molecular chromophores for organic electronic devices THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-27 US disclosed
US-12075697-B2 Inert solution-processable molecular chromophores for organic electronic devices THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-27 US disclosed
US-20220223797-A1 INERT SOLUTION-PROCESSABLE MOLECULAR CHROMOPHORES FOR ORGANIC ELECTRONIC DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-07-14 US disclosed
US-20220223797-A1 INERT SOLUTION-PROCESSABLE MOLECULAR CHROMOPHORES FOR ORGANIC ELECTRONIC DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-07-14 US disclosed
US-20220223797-A1 INERT SOLUTION-PROCESSABLE MOLECULAR CHROMOPHORES FOR ORGANIC ELECTRONIC DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-07-14 US disclosed
CN-110003234-B Dithienobenzo-isoaromatic-based hetero-condensed ring D (A-Ar)2Conjugated compound and application thereof 常州大学 2021-08-24 CN disclosed
EP-2828902-B1 INERT SOLUTION-PROCESSABLE MOLECULAR CHROMOPHORES FOR ORGANIC ELECTRONIC DEVICES UNIV CALIFORNIA (US) 2021-08-04 EP disclosed
US-20130247989-A1 INERT SOLUTION-PROCESSABLE MOLECULAR CHROMOPHORES FOR ORGANIC ELECTRONIC DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-09-26 US disclosed
WO-2013142850-A1 INERT SOLUTION-PROCESSABLE MOLECULAR CHROMOPHORES FOR ORGANIC ELECTRONIC DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-09-26 WO disclosed
US-20130026459-A1 POLYMER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-31 US disclosed
US-20130026459-A1 POLYMER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-31 US disclosed
EP-0641785-B1 TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF YAMANOUCHI PHARMA CO LTD (JP) 1999-10-27 EP disclosed
EP-0640595-B1 SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF YAMANOUCHI PHARMA CO LTD (JP) 1999-03-24 EP disclosed
US-5674886-A AROMATASE INHIBITOR; BREAST CANCER; UROGENITAL DISORDERS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1997-10-07 US disclosed
EP-0641785-A1 TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1995-03-08 EP disclosed
EP-0640595-A1 NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1995-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368173-A1 TRICYCLIC GPR65 MODULATORS GPR65, GPR3, NR1H2 ENPP2 696/4885EPAS1 1790/4885KDM4E 3978/4885
US-20130026459-A1 POLYMER COMPOUND SCO2, RER1, CRY1 ENPP2 4097/4885EPAS1 2825/4885KDM4E 3371/4885
US-20220223797-A1 INERT SOLUTION-PROCESSABLE MOLECULAR CHROMOPHORES FOR ORGANIC ELECTRONIC DEVICES KMO, TDO2, HTR3D ENPP2 4764/4885EPAS1 3478/4885KDM4E 3110/4885
US-20180355099-A1 Fluorinated Benzoxadiazole-Based Donor-Acceptor Polymers for Electronic and Photonic Applications FTO, PPOX, FOXO3 ENPP2 3781/4885EPAS1 4810/4885KDM4E 126/4885
US-12075697-B2 Inert solution-processable molecular chromophores for organic electronic devices KMO, TDO2, HTR3D ENPP2 4764/4885EPAS1 3478/4885KDM4E 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.