SCHEMBL846987

SCHEMBL846987

CC(=O)C(C)OC(=O)C(C)O

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13741382 1.00 TSHR (0.38) TSHRTP53
SCHEMBL18359697 1.00 TSHR (0.38) TSHRTP53
SCHEMBL13725057 1.00 TSHR (0.38) TSHRTP53
SCHEMBL15307351 0.95 TSHR (0.35) TSHRTP53
SCHEMBL14299354 0.95 TSHR (0.35) TSHRTP53
SCHEMBL682078 0.81 TSHR (0.39) TSHR
SCHEMBL23673200 0.79 TP53 (0.50) TSHRTP53
SCHEMBL44463 0.79 TP53 (0.50) TSHRTP53
SCHEMBL8557040 0.79 TP53 (0.50) TSHRTP53
SCHEMBL29743149 0.79 TP53 (0.50) TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4130147-A1 COMPOSITION, FILM, AND OPTICAL SENSOR FUJIFILM Corporation (JP) 2023-02-08 EP disclosed
CN-109749963-A It establishes excellent indigenous compound lactobacillus throw type leaven on the basis of strain interaction and its strengthens the method for Shanxi mature vinegar production 山西农业大学 2019-05-14 CN disclosed
US-9974303-B2 Cationic polymers for antimicrobial applications and delivery of bioactive materials INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-22 US disclosed
US-9364444-B2 Functional PLA-PEG copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging SANOFI (FR) 2016-06-14 US disclosed
US-9174923-B2 Alkyl lactyllactate solvent compositions STEPAN COMPANY (US) 2015-11-03 US disclosed
US-9133092-B2 Alkyl lactyllactates and processes of making the same STEPAN COMPANY (US) 2015-09-15 US disclosed
US-8993671-B2 Poly(aliphatic ester)-polycarbonate copolymer/polylactic acid blend Sabic Global Technolgies B.V. (NL) 2015-03-31 US disclosed
US-20150037419-A1 Functional PLA-PEG Copolymers, the Nanoparticles Thereof, Their Preparation and Use for Targeted Drug Delivery and Imaging SANOFI (FR) 2015-02-05 US disclosed
US-8940855-B2 Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-01-27 US disclosed
US-8940910-B2 Cleaning device for separating dilactide from mixtures, polymerisation device, method for separating dilactide from mixtures and use thereof UHDE INVENTA-FISCHER GMBH (DE) 2015-01-27 US disclosed
US-20120172603-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-05 US disclosed
US-20120172602-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-05 US disclosed
US-20120172559-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-05 US disclosed
US-8143369-B2 Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-27 US disclosed
US-20120046437-A1 METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-02-23 US disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100298578-A1 Catalyst For Direct Conversion Of Esters Of Lactic Acid To Lactide And The Method For Producing Lactide Using The Same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2010-11-25 US disclosed
US-20090200511-A1 Alkyl Lactyllactates and Processes of Making the Same STEPAN COMPANY 2009-08-13 US disclosed
US-20090198038-A1 Novel Catalysts for the Polymerisation of Carbonyl-Containing or Cyclic Monomers THE UNIVERSITY OF NOTTINGHAM (GB) 2009-08-06 US disclosed
US-20090173917-A1 Alkyl Lactyllactate Solvent Compositions STEPAN COMPANY 2009-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172603-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA TSHR 1728/4885TP53 4006/4885
US-20090200511-A1 Alkyl Lactyllactates and Processes of Making the Same LCT, LMAN1, ELOVL6 TSHR 3407/4885TP53 2140/4885
US-20090198038-A1 Novel Catalysts for the Polymerisation of Carbonyl-Containing or Cyclic Monomers LDHA, ME3, CBR3 TSHR 4596/4885TP53 3844/4885
US-20100298578-A1 Catalyst For Direct Conversion Of Esters Of Lactic Acid To Lactide And The Method For Producing Lactide Using The Same LDHA, LDHB, LPO TSHR 268/4885TP53 2046/4885
US-20090173917-A1 Alkyl Lactyllactate Solvent Compositions LCT, UGT8, SI TSHR 4145/4885TP53 3414/4885
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA TSHR 1728/4885TP53 4006/4885
US-20120046437-A1 METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR OGFOD1, PCNA, ODC1 TSHR 4297/4885TP53 2355/4885
US-20120172602-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA TSHR 1728/4885TP53 4006/4885
US-20150037419-A1 Functional PLA-PEG Copolymers, the Nanoparticles Thereof, Their Preparation and Use for Targeted Drug Delivery and Imaging NAPEPLD, LPXN, PCNP TSHR 4575/4885TP53 431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.