Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634165 | 0.87 | ESR1 (0.39) | HPGDKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8633203 | 0.84 | MEN1 (0.35) | KMT2AMEN1POLB | |
| SCHEMBL7764017 | 0.84 | SLC9A1 (0.56) | — | |
| SCHEMBL8635496 | 0.83 | ALDH1A1 (0.39) | KMT2AALDH1A1LMNAMAPTPOLB | |
| SCHEMBL8635012 | 0.82 | NSD2 (0.36) | MAPTPOLB | |
| SCHEMBL8635768 | 0.81 | ALDH1A1 (0.37) | ALDH1A1LMNAPOLB | |
| SCHEMBL8632865 | 0.81 | RORC (0.36) | KMT2AMAPT | |
| SCHEMBL8634267 | 0.80 | KEAP1 (0.41) | KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8635339 | 0.80 | MTNR1A (0.42) | ALDH1A1LMNA | |
| SCHEMBL8635192 | 0.77 | RXRA (0.35) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |