Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630425 | 0.76 | TSHR (0.44) | HRH2HRH1CYP1A2GAACYP2C9 | |
| SCHEMBL7425708 | 0.62 | MKNK1 (0.72) | LSSMAPK14MKNK1MKNK2 | |
| SCHEMBL8328609 | 0.62 | SMN1; SMN2 (0.43) | PKMLDHAHSD17B10PPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL6199874 | 0.61 | L3MBTL1 (0.62) | LSSMAPK14PKMMKNK1MKNK2 | |
| SCHEMBL10384362 | 0.60 | HTR3E (0.49) | HTR3AGAAHSD17B10 | |
| SCHEMBL7967170 | 0.60 | PLD1 (0.43) | HTR3AMAPK14MAPK11CYP1A2CYP2C19 | |
| SCHEMBL4745377 | 0.59 | CA2 (0.38) | GAAPKMHSD17B10 | |
| SCHEMBL24990328 | 0.59 | ADRB2 (0.78) | HTR3AROCK2 | |
| SCHEMBL14076366 | 0.59 | LDHA (0.58) | LDHAALOX15HSD17B10 | |
| SCHEMBL7318615 | 0.59 | OPRD1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |