Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCKDK | O14874 | 2/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15697510 | 0.88 | MCL1 (0.55) | BCKDKMCL1RXFP1BCL2L1TBXAS1 | |
| SCHEMBL869233 | 0.88 | BCKDK (0.50) | BCKDKMCL1RXFP1BCL2L1MGLL | |
| SCHEMBL31194453 | 0.88 | BCKDK (0.50) | BCKDKMCL1RXFP1BCL2L1MGLL | |
| SCHEMBL3627055 | 0.83 | CYP2C9 (0.45) | BCKDKMCL1RXFP1BCL2L1CYP2C9 | |
| SCHEMBL121465 | 0.83 | BCKDK (0.48) | BCKDKMCL1RXFP1BCL2L1CYP2C9 | |
| SCHEMBL25284722 | 0.82 | ALDH1A1 (0.47) | BCKDKMCL1RXFP1BCL2L1CYP2C9 | |
| SCHEMBL31079515 | 0.82 | ALDH1A1 (0.47) | BCKDKMCL1RXFP1BCL2L1CYP2C9 | |
| SCHEMBL2721181 | 0.82 | GPR35 (0.54) | BCKDKMCL1RXFP1BCL2L1TBXAS1 | |
| SCHEMBL28836579 | 0.80 | LMNA (0.48) | BCKDKMCL1RXFP1BCL2L1CYP2C9 | |
| SCHEMBL30099150 | 0.80 | LMNA (0.48) | BCKDKMCL1RXFP1BCL2L1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346575-A1 | ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2025-11-13 | — | — | US | disclosed |
| EP-4431505-A1 | ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF | Korea Research Institute of Chemical Technology (KR) | 2024-09-18 | — | — | EP | disclosed |
| CN-118234721-A | Isoindolinone derivative with glutarimide mother nucleus and application thereof | 韩国化学研究院 | 2024-06-21 | — | — | CN | disclosed |
| WO-2023085785-A1 | ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF | 한국화학연구원 | 2023-05-19 | — | — | WO | disclosed |
| CN-107810186-B | Pesticidally active tetracyclic derivatives with sulfur-containing substituents | 先正达参股股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| US-10494368-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-12-03 | — | — | US | disclosed |
| EP-3317275-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| EP-3317275-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| EP-3268361-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| US-10202380-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-12 | — | — | US | disclosed |
| US-8513423-B2 | Piperidin-4-yl-azetidine diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA, NV (BE) | 2013-08-20 | — | — | US | disclosed |
| EP-2621918-A1 | OXOPIPERAZINE-AZETIDINE AMIDES AND OXODIAZEPINE-AZETIDINE AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2013-08-07 | — | — | EP | disclosed |
| US-20130102584-A1 | PIPERIDIN-4-YL-AZETIDINE DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA, NV (BE) | 2013-04-25 | — | — | US | disclosed |
| US-20130102584-A1 | PIPERIDIN-4-YL-AZETIDINE DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA, NV (BE) | 2013-04-25 | — | — | US | disclosed |
| US-20130085130-A1 | MONOACYLGLYCEROL LIPASE INHIBITORS FOR THE TREATMENT OF METABOLIC DISEASES AND RELATED DISORDERS | JANSSEN PHARMACEUTICA NV (US) | 2013-04-04 | — | — | US | disclosed |
| WO-2013049293-A1 | MONOACYLGLYCEROL LIPASE INHIBITORS FOR THE TREATMENT OF METABOLIC DISEASES AND RELATED DISORDERS | JANSSEN PHARMACEUTICA NV (BE) | 2013-04-04 | — | — | WO | disclosed |
| WO-2012054716-A1 | PIPERIDIN-4-YL-AZETIDINE DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV. (BE) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012054716-A1 | PIPERIDIN-4-YL-AZETIDINE DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV. (BE) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012044613-A1 | OXOPIPERAZINE-AZETIDINE AMIDES AND OXODIAZEPINE-AZETIDINE AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-04-05 | — | — | WO | disclosed |
| US-20120077797-A1 | OXOPIPERAZINE-AZETIDINE AMIDES AND OXODIAZEPINE-AZETIDINE AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077797-A1 | OXOPIPERAZINE-AZETIDINE AMIDES AND OXODIAZEPINE-AZETIDINE AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | LPL, PNLIP, LIPA | BCKDK 791/4885MCL1 3086/4885RXFP1 2280/4885 |
| US-20130085130-A1 | MONOACYLGLYCEROL LIPASE INHIBITORS FOR THE TREATMENT OF METABOLIC DISEASES AND RELATED DISORDERS | PNLIP, LIPC, LPL | BCKDK 392/4885MCL1 3827/4885RXFP1 3133/4885 |
| US-10202380-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | DDT, TST, ACHE | BCKDK 3779/4885MCL1 2956/4885RXFP1 4249/4885 |
| US-10494368-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | DDT, TST, ACHE | BCKDK 3765/4885MCL1 2587/4885RXFP1 4231/4885 |
| US-20130102584-A1 | PIPERIDIN-4-YL-AZETIDINE DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | PNLIP, LPL, MGLL | BCKDK 1399/4885MCL1 1965/4885RXFP1 1372/4885 |
| US-20250346575-A1 | ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF | CRBN, IDH1, IDH2 | BCKDK 2128/4885MCL1 121/4885RXFP1 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.