Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 2/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466249 | 0.90 | LMNA (0.48) | LMNAALDH1A1TSHRTRPA1 | |
| Propylene Glycol SCHEMBL28742991 | 0.88 | TDP1 (0.42) | LMNAALDH1A1TSHRTRPA1TDP1 | |
| Propylene Glycol SCHEMBL872897 | 0.79 | LMNA (0.52) | LMNATSHRTDP1 | |
| SCHEMBL1200514 | 0.78 | TSHR (0.58) | LMNAALDH1A1TSHR | |
| Propylene Glycol SCHEMBL9721324 | 0.78 | LMNA (0.46) | LMNAALDH1A1TSHRTRPA1TDP1 | |
| SCHEMBL3673217 | 0.78 | LMNA (0.46) | LMNAALDH1A1TSHRTRPA1 | |
| SCHEMBL3673215 | 0.78 | LMNA (0.46) | LMNAALDH1A1TSHRTRPA1 | |
| Propylene Glycol SCHEMBL9621813 | 0.77 | LMNA (0.50) | LMNAALDH1A1TSHRTDP1 | |
| Propylene Glycol SCHEMBL118981 | 0.76 | LMNA (0.67) | LMNAALDH1A1TSHRTDP1 | |
| Hexanal SCHEMBL873343 | 0.75 | TSHR (0.48) | LMNAALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12496370-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2025-12-16 | — | — | US | claimed |
| CN-119111761-A | Guava essence and preparation method thereof | 东莞奇易香料有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-118266623-A | Apple-flavored essence and electronic cigarette tobacco tar and preparation method thereof | 比亚迪精密制造有限公司 | 2024-07-02 | — | — | CN | claimed |
| US-11806448-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2023-11-07 | — | — | US | claimed |
| US-20260078079-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES | OSMO LABS PBC (US) | 2026-03-19 | — | — | US | disclosed |
| US-20260069734-A1 | FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS | ARYLESSENCE INC (US) | 2026-03-12 | — | — | US | disclosed |
| CN-119111761-B | Guava essence and preparation method thereof | 东莞奇易香料有限公司 | 2026-02-24 | — | — | CN | disclosed |
| US-20260028554-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES | OSMO LABS PBC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12496370-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2025-12-16 | — | — | US | disclosed |
| US-20250313523-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES | OSMO LABS, PBC | 2025-10-09 | — | — | US | disclosed |
| US-20250236810-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING BENZENE DERIVATIVES | OSMO LABS, PBC | 2025-07-24 | — | — | US | disclosed |
| US-20250234910-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES | OSMO LABS, PBC | 2025-07-24 | — | — | US | disclosed |
| US-20090092571-A1 | LIQUID DEODORANT COMPOSITION AND DEODORIZING METHOD | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20090087401-A1 | DEODORANT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| EP-2042198-A1 | LIQUID DEODORANT COMPOSITION AND METHOD OF DEODORIZING | Takasago International Corporation (JP) | 2009-04-01 | — | — | EP | disclosed |
| US-20070092623-A1 | Food products containing a fruit component | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1689256-A1 | FOOD PRODUCTS CONTAINING A FRUIT COMPONENT | Takasago International Corporation (JP) | 2006-08-16 | — | — | EP | disclosed |
| US-20060165622-A1 | Deodorant composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1561476-A1 | DEODORANT COMPOSITION | Takasago International Corporation (JP) | 2005-08-10 | — | — | EP | disclosed |
| WO-2005048743-A1 | FOOD PRODUCTS CONTAINING A FRUIT COMPONENT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313523-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES | CYP8B1, CYP1B1, BBOX1 | LMNA 2153/4885ALDH1A1 117/4885TSHR 4274/4885 |
| US-20250236810-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING BENZENE DERIVATIVES | BBOX1, NISCH, TAS2R4 | LMNA 2640/4885ALDH1A1 186/4885TSHR 4188/4885 |
| US-20260028554-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES | TAS2R42, TAS2R4, TAS2R41 | LMNA 1935/4885ALDH1A1 868/4885TSHR 2405/4885 |
| US-20260069734-A1 | FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS | FFAR1, FFAR2, FFAR3 | LMNA 399/4885ALDH1A1 697/4885TSHR 1822/4885 |
| US-20260078079-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES | CBR1, CBR3, TAS2R1 | LMNA 2153/4885ALDH1A1 804/4885TSHR 1119/4885 |
| US-20250234910-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES | TAS1R3, TAS2R5, TRPA1 | LMNA 3115/4885ALDH1A1 117/4885TSHR 998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.