Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368545 | 0.93 | NPC1 (0.39) | ATMCTNNB1HPGDPOLBGAA | |
| SCHEMBL18543043 | 0.91 | LMNA (0.52) | ATMCTNNB1GAALMNANPC1 | |
| SCHEMBL8738575 | 0.89 | MAPT (0.42) | ATMHPGDGAALMNANPC1 | |
| SCHEMBL18649325 | 0.86 | HPGD (0.44) | ATMCTNNB1HPGDPOLBGAA | |
| SCHEMBL23344687 | 0.85 | LMNA (0.46) | ATMCTNNB1GAALMNANPC1 | |
| SCHEMBL13621280 | 0.85 | ATM (0.45) | ATMCTNNB1HPGDPOLBGAA | |
| SCHEMBL22763282 | 0.82 | CMA1 (0.42) | ATMPOLBGAANPC1MAPK1 | |
| SCHEMBL13657391 | 0.81 | KDM4E (0.46) | ATMLMNANPC1MAPK1CASP3 | |
| SCHEMBL26078414 | 0.81 | CHRM2 (0.40) | ATMLMNANPC1MAPK1CASP3 | |
| SCHEMBL84835 | 0.80 | TRPV1 (0.49) | MAPK1RAB9ASMN1; SMN2TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807614-B1 | Method for making substituted furan compound embodiments and derivatives thereof | TRIAD NATIONAL SECURITY, LLC (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230318040-A1 | ALUMINUM-ETHER-BASED COMPOSITION FOR BATTERIES AND AMBIENT TEMPERATURE ALUMINUM DEPOSITION | BATTELLE MEMORIAL INSTITUTE (US) | 2023-10-05 | — | — | US | disclosed |
| US-20230303577-A1 | TEMOZOLOMIDE ANALOGS AND METHODS OF USE | ST. JOHN'S CANCER INSTITUTE (US) | 2023-09-28 | — | — | US | disclosed |
| US-11739178-B2 | Nanohoop-functionalized polymer embodiments and methods of making and using the same | UNIVERSITY OF OREGON (US) | 2023-08-29 | — | — | US | disclosed |
| US-11708377-B2 | Analogues and derivatives of cephalotaxine and methods for making and using the compounds | OREGON STATE UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
| US-11680152-B2 | Recyclable polymers from environmentally benign building blocks | TRIAD NATIONAL SECURITY, LLC (US) | 2023-06-20 | — | — | US | disclosed |
| US-20220176337-A1 | SYSTEM AND METHOD USING PHOTOCHEMICAL OXYGEN STORAGE AND RELEASE | PORTLAND STATE UNIVERSITY (US) | 2022-06-09 | — | — | US | disclosed |
| US-11345950-B2 | Probe for selectively characterizing enzymes involved in xenobiotic metabolism and method of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2022-05-31 | — | — | US | disclosed |
| US-20220152065-A1 | METHOD OF BLOCKING OR AMELIORATING CYTOKINE RELEASE SYNDROME | RIGEL PHARMACEUTICALS, INC. (US) | 2022-05-19 | — | — | US | disclosed |
| US-11332451-B2 | RIP1 inhibitory compounds and methods for making and using the same | RIGEL PHARMACEUTICALS, INC. (GA) | 2022-05-17 | — | — | US | disclosed |
| US-9611276-B2 | Imidazo bicyclic iminium compounds as antitumor agents | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-04-04 | — | — | US | disclosed |
| US-9562019-B2 | Substituted pyridazines as EGFR and/or KRAS inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-02-07 | — | — | US | disclosed |
| US-8318755-B2 | Inhibitors of SYK and JAK protein kinases | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| US-8268992-B2 | Thiolactams and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-8217029-B2 | Oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD (CH) | 2012-07-10 | — | — | US | disclosed |
| US-20120130073-A1 | INHIBITORS OF SYK AND JAK PROTEIN KINASES | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-24 | — | — | US | disclosed |
| US-20110257157-A1 | THIOLACTAMS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| US-20110112098-A1 | MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-05-12 | — | — | US | disclosed |
| US-20110039823-A1 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-02-17 | — | — | US | disclosed |
| US-7312209-B2 | Acridone inhibitors of IMPDH enzyme | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345950-B2 | Probe for selectively characterizing enzymes involved in xenobiotic metabolism and method of making and using the same | CYP2E1, CYP1A1, CYP7A1 | ATM 4592/4885CTNNB1 3141/4885HPGD 419/4885 |
| US-20120130073-A1 | INHIBITORS OF SYK AND JAK PROTEIN KINASES | SYK, BTK, JAK1 | ATM 377/4885CTNNB1 2640/4885HPGD 3007/4885 |
| US-20110257157-A1 | THIOLACTAMS AND USES THEREOF | PLK3, PLK4, PLK2 | ATM 1919/4885CTNNB1 1310/4885HPGD 2669/4885 |
| US-20110039823-A1 | OXAZOLIDINONE ANTIBIOTICS | OXA1L, XDH, UBE2D3 | ATM 3315/4885CTNNB1 3490/4885HPGD 631/4885 |
| US-20220152065-A1 | METHOD OF BLOCKING OR AMELIORATING CYTOKINE RELEASE SYNDROME | TSLP, IL1B, IL6 | ATM 1734/4885CTNNB1 2921/4885HPGD 1652/4885 |
| US-20230303577-A1 | TEMOZOLOMIDE ANALOGS AND METHODS OF USE | MGMT, TOP2B, IDH3B | ATM 249/4885CTNNB1 2903/4885HPGD 805/4885 |
| US-11332451-B2 | RIP1 inhibitory compounds and methods for making and using the same | RIPK1, RIPK2, RIPK3 | ATM 1440/4885CTNNB1 4534/4885HPGD 3518/4885 |
| US-11708377-B2 | Analogues and derivatives of cephalotaxine and methods for making and using the compounds | SLC6A2, NAPRT, SLC6A3 | ATM 4443/4885CTNNB1 3209/4885HPGD 348/4885 |
| US-11807614-B1 | Method for making substituted furan compound embodiments and derivatives thereof | FDPS, FLAD1, BLVRB | ATM 4303/4885CTNNB1 2255/4885HPGD 879/4885 |
| US-20110112098-A1 | MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES | SYK, BTK, TYRO3 | ATM 930/4885CTNNB1 3854/4885HPGD 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.