SCHEMBL9108340

SCHEMBL9108340

CCONC(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.42
CA7 P43166 2/20 0.42
CA12 O43570 2/20 0.42
CA14 Q9ULX7 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
CA2 P00918 2/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
APLNR P35414 1/20 0.38
CTSK P43235 4/20 0.38
CTSS P25774 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20464123 0.83 CA1 (0.43) CA1CA7CA12CA14TDP1
SCHEMBL13357351 0.80 TDP1 (0.40) CA1CA7CA12CA14TDP1
SCHEMBL1865098 0.79 CTSK (0.42) CA1CA7CA12CA14TDP1
SCHEMBL26394273 0.79 LMNA (0.36) CA1CA7CA12CA14TDP1
SCHEMBL16747755 0.79 APLNR (0.41) CA1CA7CA12CA14TDP1
SCHEMBL17770818 0.79 TDP1 (0.38) CA1CA7CA12CA14TDP1
SCHEMBL3709339 0.78 TDP1 (0.47) CA1CA7CA12CA14TDP1
SCHEMBL12155186 0.78 APLNR (0.43) CA1CA7CA12CA14TDP1
SCHEMBL307685 0.78 APLNR (0.43) CA1CA7CA12CA14TDP1
SCHEMBL14077932 0.78 MAOA (0.45) CA1CA7CA12CA14TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105778021-B Beta-cyclodextrin base star polymer and preparation method and its unimolecular micelle diagnosis and treatment integral system 华南理工大学 2018-07-10 CN claimed
CN-105778021-A Beta-cyclodextrin based star-shaped polymer and preparation method thereof, and single-molecule micelle diagnosis and treatment integrated system based on star-shaped polymer and preparation method thereof 华南理工大学 2016-07-20 CN claimed
US-12570610-B2 Macromolecule-supported aminobenzazepine compounds BOLT BIOTHERAPEUTICS, INC. (US) 2026-03-10 US disclosed
US-20250263392-A1 AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2025-08-21 US disclosed
US-20220315537-A1 MACROMOLECULE-SUPPORTED AMINOBENZAZEPINE COMPOUNDS BOLT BIOTHERAPEUTICS, INC. (US) 2022-10-06 US disclosed
CN-114585390-A Aminobenzazepine compounds, immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2022-06-03 CN disclosed
EP-3983082-A1 AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF Bolt Biotherapeutics, Inc. (US) 2022-04-20 EP disclosed
EP-3983080-A1 MACROMOLECULE-SUPPORTED AMINOBENZAZEPINE COMPOUNDS Bolt Biotherapeutics, Inc. (US) 2022-04-20 EP disclosed
US-20210228530-A1 TAXANE-LIPID-POLYSACCHARIDE DUAL CONJUGATES, PREPARATION METHODS THEREOF AND USES THEREOF SANTOLECAN PHARMACEUTICALS LLC 2021-07-29 US disclosed
EP-3812376-A1 PACLITAXEL-LIPID-POLYSACCHARIDE DUAL-TYPE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Santolecan Pharmaceuticals LLC (US) 2021-04-28 EP disclosed
US-20200390899-A1 AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2020-12-17 US disclosed
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. 2014-12-18 US disclosed
WO-2013181217-A2 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. (US) 2013-12-05 WO disclosed
EP-2646423-A1 NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES Galleon Pharmaceuticals, Inc. (US) 2013-10-09 EP disclosed
US-20130231479-A1 ARYLOXYUREA COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. 2013-09-05 US disclosed
US-8487080-B2 Fluorine-labeled compounds GENERAL ELECTRIC COMPANY (US) 2013-07-16 US disclosed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US disclosed
WO-2012074999-A1 NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. (US) 2012-06-07 WO disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed
CN-1905867-A Facially amphiphilic polymers and oligomers and uses thereof UNIV PENNSYLVANIA (US) 2007-01-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263392-A1 AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF IDO2, IDO1, BCR CA1 1129/4885CA7 1687/4885CA12 453/4885
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases MTNR1B, CHRM3, ADRA2C CA1 2685/4885CA7 1465/4885CA12 1901/4885
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases PER2, SMPD4, NDUFB5 CA1 1181/4885CA7 1085/4885CA12 671/4885
US-20130231479-A1 ARYLOXYUREA COMPOUND AND PEST CONTROL AGENT DDT, FOXO3, PNPO CA1 4185/4885CA7 2979/4885CA12 4717/4885
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES PER2, MTNR1B, NDUFB5 CA1 1016/4885CA7 1196/4885CA12 563/4885
US-20220315537-A1 MACROMOLECULE-SUPPORTED AMINOBENZAZEPINE COMPOUNDS CCNB1, CCNB2, MUS81 CA1 2237/4885CA7 3535/4885CA12 998/4885
US-20200390899-A1 AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF IDO2, IDO1, BCR CA1 1129/4885CA7 1687/4885CA12 453/4885
US-20210228530-A1 TAXANE-LIPID-POLYSACCHARIDE DUAL CONJUGATES, PREPARATION METHODS THEREOF AND USES THEREOF DDOST, UGT2B17, UGT1A7 CA1 2534/4885CA7 589/4885CA12 668/4885
US-12570610-B2 Macromolecule-supported aminobenzazepine compounds BCL6, CLTB, MET CA1 1116/4885CA7 2544/4885CA12 684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.