Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 known ✓ | P51582 | 4/20 | 0.41 |
| ▸ | P2RY2 known ✓ | P41231 | 3/20 | 0.41 |
| ▸ | P2RY12 known ✓ | Q9H244 | 2/20 | 0.39 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.36 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329784 | 0.82 | L3MBTL1 (0.47) | L3MBTL1GAAPRKCICA12CA1 | |
| SCHEMBL9644228 | 0.81 | L3MBTL1 (0.46) | L3MBTL1GAAPRKCICA12CA1 | |
| SCHEMBL8492152 | 0.79 | L3MBTL1 (0.44) | L3MBTL1GAAPRKCICA12CA1 | |
| SCHEMBL155726 | 0.79 | RAPGEF4 (0.45) | L3MBTL1GAAPRKCIACHEPOLB | |
| SCHEMBL7098523 | 0.78 | L3MBTL1 (0.45) | L3MBTL1GAAP2RY12FTOCA12 | |
| SCHEMBL9313745 | 0.78 | RAPGEF4 (0.44) | L3MBTL1GAAPRKCIACHEPOLB | |
| SCHEMBL14989104 | 0.77 | L3MBTL1 (0.66) | L3MBTL1P2RY4P2RY2P2RY12POLB | |
| SCHEMBL4639283 | 0.76 | ALDH1A1 (0.42) | L3MBTL1GAAPRKCIACHEPOLB | |
| SCHEMBL3396550 | 0.76 | L3MBTL1 (0.44) | L3MBTL1P2RY12FTOCA12CA1 | |
| SCHEMBL29386214 | 0.76 | L3MBTL1 (0.44) | L3MBTL1P2RY12FTOCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338319-A | Process for the photochemical and thermal stabilization of polyamide fibre material with a copper complex having fibre-affinity and an oxalic acid diarylamide | CIBA-GEIGY CORPORATION (US) | 1994-08-16 | — | — | US | disclosed |
| US-5241109-A | Photochemical and thermal stabilizers for use in dyeing polyamide fibers | CIBA-GEIGY CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |