Phosphonic Acid

Phosphonic Acid

SCHEMBL942478

CC(O)P(=O)([O-])[O-].O=[PH]([O-])[O-].[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7932016 0.88
SCHEMBL6686090 0.82 SLC34A1 (0.35) LMNA
Potassium Ion SCHEMBL3983738 0.82
Phosphoric Acid SCHEMBL28353739 0.72 LMNA (0.46) LMNA
Phosphonic Acid SCHEMBL11781168 0.70 GABRR1 (0.31)
SCHEMBL11022013 0.69
Phosphoric Acid SCHEMBL27767980 0.69 SLC34A1 (0.53) LMNA
SCHEMBL28476793 0.69 LMNA (0.32) LMNA
Propylene Glycol SCHEMBL29008138 0.69 TDP1 (0.59) LMNA
Phosphonic Acid SCHEMBL7193169 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534272-B2 Agent for oxidative treatment, particularly in transparent gel form WELLA AG (DE) 2009-05-19 US claimed
EP-1732505-B1 OXIDATIVE TREATMENT AGENT, PARTICULARLY IN THE FORM OF A TRANSPARENT GEL WELLA AG (DE) 2008-12-24 EP claimed
EP-1893296-A1 PRODUCT RELEASE SYSTEM FOR ATOMIZING COMPOSITIONS CONTAINING HAIR-KERATIN-REDUCING OR OXIDATIVE ACTIVE INGREDIENTS Wella Aktiengesellschaft (DE) 2008-03-05 EP claimed
US-20080038206-A1 Product release system for atomizing compositions containing hair-keratin-reducing or oxidative active ingredients PROCTER & GAMBLE COMPANY, THE 2008-02-14 US claimed
US-20070151044-A1 Agent for oxidative treatment, particularly in transparent gel form Wella GmbH (DE) 2007-07-05 US claimed
WO-2007002044-A1 PRODUCT RELEASE SYSTEM FOR ATOMIZING COMPOSITIONS CONTAINING HAIR-KERATIN-REDUCING OR OXIDATIVE ACTIVE INGREDIENTS THE PROCTER & GAMBLE COMPANY (US) 2007-01-04 WO claimed
US-20260021459-A1 SUBSTRATE PROCESSING DEVICE, LIQUID SUPPLY DEVICE, AND SUBSTRATE PROCESSING METHOD TOKYO OHKA KOGYO CO LTD (JP) 2026-01-22 US disclosed
EP-3578161-B1 METHOD FOR IMPROVING STORAGE STABILITY OF COSMETIC ADEKA CORP (JP) 2025-11-12 EP disclosed
EP-4620453-A1 AQUEOUS DISPERSION OF SURFACE-HYDROPHOBIZED INORGANIC POWDER AND COSMETIC PREPARATION CONTAINING SAME Nikko Chemicals Co., Ltd. (JP) 2025-09-24 EP disclosed
EP-4516317-A1 DERMATOLOGICAL TOPICAL AGENT COMPOSITION CONTAINING USEFUL COMPONENT-INCLUDING TAURINE CRYSTALS Cosmed Pharmaceutical Co., Ltd. (JP) 2025-03-05 EP disclosed
EP-3107987-B2 MACHINE DISHWASH COMPOSITION UNILEVER GLOBAL IP LTD (GB) 2024-11-06 EP disclosed
EP-4458422-A1 SKIN CARE COMPOSITION FOR APPLICATION TO SKIN Cosmed Pharmaceutical Co., Ltd. (JP) 2024-11-06 EP disclosed
US-20240252403-A1 SKIN CARE COMPOSITION FOR APPLICATION TO SKIN COSMED PHARMACEUTICAL CO., LTD. (JP) 2024-08-01 US disclosed
EP-0728469-A2 An endermic liniment SHISEIDO COMPANY LIMITED (JP) 1996-08-28 EP disclosed
EP-0487404-B1 External dermatological composition HAYASHIBARA BIOCHEM LAB (JP) 1995-10-11 EP disclosed
EP-0487404-A1 External dermatological composition KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1992-05-27 EP disclosed
US-4828766-A FROM 1-/ACYL/-ETHANE-1,1-DIPHOSPHONIC ACID BENCKISER-KNAPSACK GMBH (DE) 1989-05-09 US disclosed
EP-0068584-B1 BORON CONTAINING POLYPHOSPHONATES FOR THE TREATMENT OF CALCIFIC TUMORS THE PROCTER & GAMBLE COMPANY (US) 1985-09-25 EP disclosed
US-4399817-A Boron containing polyphosphonates for the treatment of calcific tumors THE PROCTER & GAMBLE COMPANY (US) 1983-08-23 US disclosed
EP-0068584-A1 Boron containing polyphosphonates for the treatment of calcific tumors THE PROCTER & GAMBLE COMPANY (US) 1983-01-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021459-A1 SUBSTRATE PROCESSING DEVICE, LIQUID SUPPLY DEVICE, AND SUBSTRATE PROCESSING METHOD HAO2, GFER, LPO LMNA 3012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.